New Insights into Regulatory T Cells: Exosome- and Non-Coding RNA-Mediated Regulation of Homeostasis and Resident Treg Cells

The role of immune system exhaustion on cancer cell escape and anti-tumor immune induction after irradiation

(2016) Fernando Mendes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Two FOXP3+CD4+ T cell subpopulations distinctly control the prognosis of colorectal cancers

(2016) Takuro Saito et al.   NATURE MEDICINE

Colorectal cancer cell-derived extracellular vesicles induce phenotypic alteration of T cells into tumor-growth supporting cells with transforming growth factor-β1-mediated suppression

(2016) Nami Yamada et al.   Oncotarget

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

FOXP3+ regulatory T cells and their functional regulation

(2015) Zhiyuan Li et al.   Cellular & Molecular Immunology

Phenotype and function of tissue-resident unconventional Foxp3-expressing CD4+ regulatory T cells

(2015) Jingli Lu et al.   CELLULAR IMMUNOLOGY

MiR-21 controls in situ expansion of CCR6+ regulatory T cells through PTEN/AKT pathway in breast cancer

(2015) Yan Hu et al.   IMMUNOLOGY AND CELL BIOLOGY

LncRNA HULC affects the differentiation of Treg in HBV-related liver cirrhosis

(2015) Jie Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Coexpression of TIGIT and FCRL3 Identifies Helios+Human Memory Regulatory T Cells

(2015) Khalid Bin Dhuban et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cell identity: formation and maintenance

(2015) Xudong Li et al.   TRENDS IN IMMUNOLOGY

FOXP3 is a direct target of miR15a/16 in umbilical cord blood regulatory T cells

(2014) X Liu et al.   BONE MARROW TRANSPLANTATION

Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth

(2014) Yuan Yin et al.   CELL RESEARCH

Alteration of Regulatory T Cells in Type 1 Diabetes Mellitus: A Comprehensive Review

(2014) Tingting Tan et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

(2014) Isobel S. Okoye et al.   IMMUNITY

Adipose tissue-resident regulatory T cells: phenotypic specialization, functions and therapeutic potential

(2014) Daniela Cipolletta   IMMUNOLOGY

Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection

(2014) Pablo Penaloza-MacMaster et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thymus Exosomes-Like Particles Induce Regulatory T Cells

(2014) G.-J. Wang et al.   JOURNAL OF IMMUNOLOGY

MicroRNA networks in regulatory T cells

(2014) Xuehua Tang et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells

(2014) Dhafer Mrizak et al.   JNCI-Journal of the National Cancer Institute

Emerging role of extracellular vesicles in inflammatory diseases

(2014) Edit I. Buzas et al.   Nature Reviews Rheumatology

Regulatory T Cell-Derived Exosomes: Possible Therapeutic and Diagnostic Tools in Transplantation

(2014) Akansha Agarwal et al.   Frontiers in Immunology

Organ-Specific and Memory Treg Cells: Specificity, Development, Function, and Maintenance

(2014) Iris K. Gratz et al.   Frontiers in Immunology

Up-regulation of microRNA-210 induces immune dysfunction via targeting FOXP3 in CD4+ T cells of psoriasis vulgaris

(2013) Ming Zhao et al.   CLINICAL IMMUNOLOGY

Induction, control, and plasticity of Treg cells: The immune regulatory network revised?

(2013) Vincenzo Barnaba et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+T cells contributes to their regulatory function

(2013) Lesley Ann Smyth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MicroRNA-126 regulates the induction and function of CD4+Foxp3+regulatory T cells through PI3K/AKT pathway

(2013) Andong Qin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulatory T cells in nonlymphoid tissues

(2013) Dalia Burzyn et al.   NATURE IMMUNOLOGY

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

MicroRNAs and other non-coding RNAs as targets for anticancer drug development

(2013) Hui Ling et al.   NATURE REVIEWS DRUG DISCOVERY

Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery

(2013) R. S. Paiva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The plasticity of human Treg and Th17 cells and its role in autoimmunity

(2013) Markus Kleinewietfeld et al.   SEMINARS IN IMMUNOLOGY

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors

(2012) Hyo Jin Park et al.   CELLULAR IMMUNOLOGY

Total glucosides of paeony induces regulatory CD4+CD25+ T cells by increasing Foxp3 demethylation in lupus CD4+ T cells

(2012) Ming Zhao et al.   CLINICAL IMMUNOLOGY

Microvesicles derived from mesenchymal stem cells: Potent organelles for induction of tolerogenic signaling

(2012) Aram Mokarizadeh et al.   IMMUNOLOGY LETTERS

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

(2012) Mahesh Yadav et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells

(2012) Hayato Takahashi et al.   NATURE IMMUNOLOGY

TIM-3 Expression Characterizes Regulatory T Cells in Tumor Tissues and Is Associated with Lung Cancer Progression

(2012) Xin Gao et al.   PLoS One

MicroRNA 10a Marks Regulatory T Cells

(2012) Lukas T. Jeker et al.   PLoS One

MicroRNAs are key regulators controlling iNKT and regulatory T-cell development and function

(2011) Li Zhou et al.   Cellular & Molecular Immunology

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production

(2011) A. Clayton et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells: Banned Cells for Decades

(2011) Karin Loser et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Peripheral education of the immune system by colonic commensal microbiota

(2011) Stephanie K. Lathrop et al.   NATURE

Foxp3 is critical for human natural CD4+CD25+ regulatory T cells to suppress alloimmune response

(2011) Lei Sun et al.   TRANSPLANT IMMUNOLOGY

Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

(2011) Leonora Balaj et al.   Nature Communications

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

(2011) María Mittelbrunn et al.   Nature Communications

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic-Derived from Peripherally Induced Foxp3+ T Regulatory Cells

(2010) A. M. Thornton et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

(2009) M. Gobert et al.   CANCER RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

(2009) M. Tsuji et al.   SCIENCE

miR-142-3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA

(2008) Bo Huang et al.   EMBO REPORTS

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

(2008) Mark M.W. Chong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Small intestinal CD103+dendritic cells display unique functional properties that are conserved between mice and humans

(2008) Elin Jaensson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dicer-dependent microRNA pathway safeguards regulatory T cell function

(2008) Adrian Liston et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

(2008) Xuyu Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Foxp3+regulatory T cells maintain immune homeostasis in the skin

(2008) Jan C. Dudda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

(2008) Yvonne Tay et al.   NATURE

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE