MiR-21 controls in situ expansion of CCR6+ regulatory T cells through PTEN/AKT pathway in breast cancer

The role of TGF-β1–miR-21–ROS pathway in bystander responses induced by irradiated non-small-cell lung cancer cells

(2014) Y Jiang et al.   BRITISH JOURNAL OF CANCER

miR-21 normalizes vascular smooth muscle proliferation and improves coronary collateral growth in metabolic syndrome

(2014) Rebecca Hutcheson et al.   FASEB JOURNAL

Immuno-miRs: critical regulators of T-cell development, function and ageing

(2014) Bart-Jan Kroesen et al.   IMMUNOLOGY

Differentiation of IL-17-Producing Effector and Regulatory Human T Cells from Lineage-Committed Naive Precursors

(2014) F. Mercer et al.   JOURNAL OF IMMUNOLOGY

miR-21 overexpression enhances TGF-β1-induced epithelial-to-mesenchymal transition by target smad7 and aggravates renal damage in diabetic nephropathy

(2014) Jin-Yang Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hepatitis B Virus Induces Cell Proliferation via HBx-Induced microRNA-21 in Hepatocellular Carcinoma by Targeting Programmed Cell Death Protein4 (PDCD4) and Phosphatase and Tensin Homologue (PTEN)

(2014) Preeti Damania et al.   PLoS One

Upregulation of miR-21 in Cisplatin Resistant Ovarian Cancer via JNK-1/c-Jun Pathway

(2014) Ileabett M. Echevarría-Vargas et al.   PLoS One

MicroRNA-21 (miR-21) Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by Targeting PTEN, RECK and Bcl-2 in Lung Squamous Carcinoma, Gejiu City, China

(2014) Long-feng Xu et al.   PLoS One

MicroRNAs expression profile in CCR6+regulatory T cells

(2014) Juanjuan Zhao et al.   PeerJ

The MicroRNA-21/PTEN Pathway Regulates the Sensitivity of HER2-Positive Gastric Cancer Cells to Trastuzumab

(2013) Kojiro Eto et al.   ANNALS OF SURGICAL ONCOLOGY

MicroRNA-21 accelerates hepatocyte proliferation in vitro via PI3K/Akt signaling by targeting PTEN

(2013) Bai Yan-nan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-17 92 regulates effector and memory CD8 T-cell fates by modulating proliferation in response to infections

(2013) A. A. Khan et al.   BLOOD

Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis

(2013) Linda Hammerich et al.   HEPATOLOGY

MicroRNA-126 regulates the induction and function of CD4+Foxp3+regulatory T cells through PI3K/AKT pathway

(2013) Andong Qin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets

(2013) Kate S. Smigiel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conditional Deletion of PTEN in Peripheral T Cells Augments TCR-Mediated Activation but Does Not Abrogate CD28 Dependency or Prevent Anergy Induction

(2013) F. L. Locke et al.   JOURNAL OF IMMUNOLOGY

Potential Roles of CCR5+ CCR6+ Dendritic Cells Induced by Nasal Ovalbumin plus Flt3 Ligand Expressing Adenovirus for Mucosal IgA Responses

(2013) Yoshiko Fukuyama et al.   PLoS One

miRNA Signature of Mouse Helper T Cell Hyper-Proliferation

(2013) Connie L. Sommers et al.   PLoS One

Dual Role of miR-21 in CD4+ T-Cells: Activation-Induced miR-21 Supports Survival of Memory T-Cells and Regulates CCR7 Expression in Naive T-Cells

(2013) Katarzyna Smigielska-Czepiel et al.   PLoS One

Transcriptional control of regulatory T cell development and function

(2013) Chong T. Luo et al.   TRENDS IN IMMUNOLOGY

Role of miRNAs in CD4 T cell plasticity during inflammation and tolerance

(2013) Apoorva Sethi et al.   Frontiers in Genetics

HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCR -selected mouse thymocytes

(2012) G. W. Wong et al.   BLOOD

TGF-β-miR-34a-CCL22 Signaling-Induced Treg Cell Recruitment Promotes Venous Metastases of HBV-Positive Hepatocellular Carcinoma

(2012) Pengyuan Yang et al.   CANCER CELL

TheEx VivoInduction of Human CD103+CD25hiFoxp3+CD4+and CD8+Tregs is IL-2 and TGF-β1 Dependent

(2012) B. Gunnlaugsdottir et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Silencing of microRNA-21in vivoameliorates autoimmune splenomegaly in lupus mice

(2011) Barry G. Garchow et al.   EMBO Molecular Medicine

In Situ Prior Proliferation of CD4+ CCR6+ Regulatory T Cells Facilitated by TGF-β Secreting DCs Is Crucial for Their Enrichment and Suppression in Tumor Immunity

(2011) Lin Xu et al.   PLoS One

Expansion of CD4+CD25+ regulatory T cells from cord blood CD4+ cells using the common γ-chain cytokines (IL-2 and IL-15) and rapamycin

(2010) Shinsuke Asanuma et al.   ANNALS OF HEMATOLOGY

Enrichment of CCR6+Foxp3+ regulatory T cells in the tumor mass correlates with impaired CD8+ T cell function and poor prognosis of breast cancer

(2010) Lin Xu et al.   CLINICAL IMMUNOLOGY

CCR6 Marks Regulatory T Cells as a Colon-Tropic, IL-10-Producing Phenotype

(2010) K. Kitamura et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

Human natural Treg microRNA signature: Role of microRNA‐31 and microRNA‐21 in FOXP3 expression

(2009) Redouane Rouas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells

(2009) S. Kohlhaas et al.   JOURNAL OF IMMUNOLOGY

Aberrant expression of the Th2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3 

(2008) B. Lamprecht et al.   BLOOD

Differential expression of CCR7 defines two distinct subsets of human memory CD4+CD25+ Tregs

(2008) Valeria Tosello et al.   CLINICAL IMMUNOLOGY

Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery

(2008) Tomoki Ito et al.   IMMUNITY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology