- Home
- Publications
- Publication Search
- Publication Details
Title
Telomere and Telomerase Therapeutics in Cancer
Authors
Keywords
-
Journal
Genes
Volume 7, Issue 6, Pages 22
Publisher
MDPI AG
Online
2016-05-27
DOI
10.3390/genes7060022
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells
- (2016) Daiki Hasegawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A triad of telomerase, androgen receptor and early growth response 1 in prostate cancer cells
- (2016) Sheeba Jacob et al. CANCER BIOLOGY & THERAPY
- Telomerase activity in pancreatic juice differentiates pancreatic cancer from chronic pancreatitis: A meta-analysis
- (2016) Tatsuo Hata et al. PANCREATOLOGY
- Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells
- (2016) Guangtong Zhou et al. Oncotarget
- Telomere G-Quadruplex as a Potential Target to Accelerate Telomere Shortening by Expanding the Incomplete End-Replication of Telomere DNA
- (2015) Zheng Tan et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- The G-quadruplex-stabilising agent RHPS4 induces telomeric dysfunction and enhances radiosensitivity in glioblastoma cells
- (2015) F. Berardinelli et al. DNA REPAIR
- Quantitative assessment of telomerase components in cancer cell lines
- (2015) Semih Can Akıncılar et al. FEBS LETTERS
- Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity
- (2015) Cheryl M. Koh et al. JOURNAL OF CLINICAL INVESTIGATION
- PD-1/PD-L1 Blockade Together With Vaccine Therapy Facilitates Effector T-Cell Infiltration Into Pancreatic Tumors
- (2015) Kevin C. Soares et al. JOURNAL OF IMMUNOTHERAPY
- Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells
- (2015) Ozlem Kulak et al. MOLECULAR AND CELLULAR BIOLOGY
- Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation
- (2015) Yinghui Li et al. NATURE CELL BIOLOGY
- A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis
- (2015) Ayalew Tefferi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Treating Myeloproliferation — On Target or Off?
- (2015) Mary Armanios et al. NEW ENGLAND JOURNAL OF MEDICINE
- Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia
- (2015) Gabriela M. Baerlocher et al. NEW ENGLAND JOURNAL OF MEDICINE
- Human Rap1 modulates TRF2 attraction to telomeric DNA
- (2015) Eliška Janoušková et al. NUCLEIC ACIDS RESEARCH
- Telomeric G-quadruplexes are a substrate and site of localization for human telomerase
- (2015) Aaron L. Moye et al. Nature Communications
- Immunogenicity of GX301 cancer vaccine: Four (telomerase peptides) are better than one
- (2015) Daniela Fenoglio et al. Human Vaccines & Immunotherapeutics
- A Transposable Element within the Non-canonical Telomerase RNA of Arabidopsis thaliana Modulates Telomerase in Response to DNA Damage
- (2015) Hengyi Xu et al. PLoS Genetics
- Comparative study of18F-FDG-PET/CT imaging and serum hTERT mRNA quantification in cancer diagnosis
- (2015) Bingqiong Ping et al. Cancer Medicine
- Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma
- (2015) Ryan T Pitman et al. Oncotarget
- A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer
- (2014) A. A. Chiappori et al. ANNALS OF ONCOLOGY
- Noncanonical Functions of Telomerase: Implications in Telomerase-Targeted Cancer Therapies
- (2014) Yinghui Li et al. CANCER RESEARCH
- Circulating tumor cell telomerase activity as a prognostic marker for overall survival in SWOG 0421: A phase III metastatic castration resistant prostate cancer trial
- (2014) Amir Goldkorn et al. INTERNATIONAL JOURNAL OF CANCER
- Binding of TPP1 Protein to TIN2 Protein Is Required for POT1a,b Protein-mediated Telomere Protection
- (2014) David Frescas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Circulating Tumor Cell Counts Are Prognostic of Overall Survival in SWOG S0421: A Phase III Trial of Docetaxel With or Without Atrasentan for Metastatic Castration-Resistant Prostate Cancer
- (2014) Amir Goldkorn et al. JOURNAL OF CLINICAL ONCOLOGY
- A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish
- (2014) Francisca Alcaraz-Pérez et al. Nature Communications
- Functional characterization of the TERRA transcriptome at damaged telomeres
- (2014) Antonio Porro et al. Nature Communications
- A multi-peptide, dual-adjuvant telomerase vaccine (GX301) is highly immunogenic in patients with prostate and renal cancer
- (2013) Daniela Fenoglio et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- A Genetically Engineered Oncolytic Adenovirus Decoys and Lethally Traps Quiescent Cancer Stem-like Cells in S/G2/M Phases
- (2013) S. Yano et al. CLINICAL CANCER RESEARCH
- A Multicenter Randomized Phase IIb Efficacy Study of Vx-001, a Peptide-Based Cancer Vaccine as Maintenance Treatment in Advanced Non–Small-Cell Lung Cancer: Treatment Rationale and Protocol Dynamics
- (2013) Vassilis Georgoulias et al. Clinical Lung Cancer
- Correlation between chemosensitivity to anticancer drugs and telomerase reverse transcriptase mRNA expression in gastric cancer
- (2013) Lin Wang et al. Diagnostic Pathology
- Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NF-κB-dependent transcription
- (2013) Deqiang Ding et al. FASEB JOURNAL
- Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence
- (2013) Bettina Balk et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Frequency of TERT promoter mutations in human cancers
- (2013) João Vinagre et al. Nature Communications
- A phase II open label trial evaluating safety and efficacy of a telomerase peptide vaccination in patients with advanced hepatocellular carcinoma
- (2012) Tim F Greten et al. BMC CANCER
- Oral Cancer Diagnosis via a Ferrocenylnaphthalene Diimide-Based Electrochemical Telomerase Assay
- (2012) K. Mori et al. CLINICAL CHEMISTRY
- Human Rap1 Interacts Directly with Telomeric DNA and Regulates TRF2 Localization at the Telomere
- (2012) N. Özlem Arat et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting Protein Kinase C (PKC) and Telomerase by Phenethyl Isothiocyanate (PEITC) Sensitizes PC-3 Cells Towards Chemotherapeutic Drug-Induced Apoptosis
- (2012) Sutapa Mukherjee et al. JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY
- Telomerase directly regulates NF-κB-dependent transcription
- (2012) Arkasubhra Ghosh et al. NATURE CELL BIOLOGY
- Tankyrase-targeted therapeutics: expanding opportunities in the PARP family
- (2012) Jenna L. Riffell et al. NATURE REVIEWS DRUG DISCOVERY
- DNA secondary structures: stability and function of G-quadruplex structures
- (2012) Matthew L. Bochman et al. NATURE REVIEWS GENETICS
- Telomerase reverse transcriptase promotes epithelial–mesenchymal transition and stem cell-like traits in cancer cells
- (2012) Z Liu et al. ONCOGENE
- Cell-Free Circulating Plasma hTERT mRNA Is a Useful Marker for Prostate Cancer Diagnosis and Is Associated with Poor Prognosis Tumor Characteristics
- (2012) José A. March-Villalba et al. PLoS One
- Telomerase and the search for the end of cancer
- (2012) Simone Mocellin et al. TRENDS IN MOLECULAR MEDICINE
- Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001
- (2012) Else-Marit Inderberg-Suso et al. OncoImmunology
- Noninvasive and real-time monitoring of the therapeutic response of tumors in vivo with an optimized hTERT promoter
- (2011) Song-Tao Yu et al. CANCER
- Telomerase Peptide Vaccination in NSCLC: A Phase II Trial in Stage III Patients Vaccinated after Chemoradiotherapy and an 8-Year Update on a Phase I/II Trial
- (2011) P. F. Brunsvig et al. CLINICAL CANCER RESEARCH
- Mutant telomerase RNAs induce DNA damage and apoptosis via the TRF2-ATM pathway in telomerase-overexpressing primary fibroblasts
- (2011) Dashayini Mahalingam et al. FEBS Journal
- Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita
- (2011) F. Zhong et al. GENES & DEVELOPMENT
- Sequential Administration of the Native TERT572 Cryptic Peptide Enhances the Immune Response Initiated by its Optimized Variant TERT572Y in Cancer Patients
- (2011) Eleni-Kyriaki Vetsika et al. JOURNAL OF IMMUNOTHERAPY
- N-Cyclic Bay-Substituted Perylene G-Quadruplex Ligands Have Selective Antiproliferative Effects on Cancer Cells and Induce Telomere Damage
- (2011) Valentina Casagrande et al. JOURNAL OF MEDICINAL CHEMISTRY
- Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines
- (2011) Jun Fujimori et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer
- (2011) Diego Serrano et al. Molecular Cancer
- hTERT Promotes Imatinib Resistance in Chronic Myeloid Leukemia Cells: Therapeutic Implications
- (2011) L. Deville et al. MOLECULAR CANCER THERAPEUTICS
- G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase
- (2011) Q. Wang et al. NUCLEIC ACIDS RESEARCH
- T-Oligos Inhibit Growth and Induce Apoptosis in Human Ovarian Cancer Cells
- (2011) Sibaji Sarkar et al. OLIGONUCLEOTIDES
- Introduction of SV40ER and hTERT into mammospheres generates breast cancer cells with stem cell properties
- (2011) A N Paranjape et al. ONCOGENE
- Separation of telomerase functions by reverse genetics
- (2011) S. Mukherjee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prostate tumor cells with cancer progenitor properties have high telomerase activity and are rapidly killed by telomerase interference
- (2011) Tong Xu et al. PROSTATE
- Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination on the basis of hTERT and survivin after ASCT for myeloma
- (2010) A. P. Rapoport et al. BLOOD
- A Cancer Detection Platform Which Measures Telomerase Activity from Live Circulating Tumor Cells Captured on a Microfilter
- (2010) T. Xu et al. CANCER RESEARCH
- The Telomerase Inhibitor Imetelstat Depletes Cancer Stem Cells in Breast and Pancreatic Cancer Cell Lines
- (2010) I. Joseph et al. CANCER RESEARCH
- Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development
- (2010) Koji Waki et al. CANCER SCIENCE
- The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth
- (2010) C. O. Marian et al. CLINICAL CANCER RESEARCH
- Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial
- (2010) Redas Trepiakas et al. CYTOTHERAPY
- The effects of telomerase inhibition on prostate tumor-initiating cells
- (2010) Calin O. Marian et al. INTERNATIONAL JOURNAL OF CANCER
- Preclinical Evaluation of Differentially Targeting Dual Virotherapy for Human Solid Cancer
- (2010) R. Sakai et al. MOLECULAR CANCER THERAPEUTICS
- Reprogramming Murine Telomerase Rapidly Inhibits the Growth of Mouse Cancer Cells In vitro and In vivo
- (2010) T. Xu et al. MOLECULAR CANCER THERAPEUTICS
- Telomerase activity-independent function of TERT allows glioma cells to attain cancer stem cell characteristics by inducing EGFR expression
- (2010) Samuel Beck et al. MOLECULES AND CELLS
- The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
- (2010) Sophie Redon et al. NUCLEIC ACIDS RESEARCH
- (S)-Stereoisomer of telomestatin as a potent G-quadruplex binder and telomerase inhibitor
- (2010) Takayuki Doi et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Association of telomerase activity with radio- and chemosensitivity of neuroblastomas
- (2010) Simone Wesbuer et al. Radiation Oncology
- Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis
- (2009) D. Drygin et al. CANCER RESEARCH
- Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1
- (2009) Yoon Ra Her et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Phase I Study of Telomerase-specific Replication Competent Oncolytic Adenovirus (Telomelysin) for Various Solid Tumors
- (2009) John Nemunaitis et al. MOLECULAR THERAPY
- A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis
- (2009) A. S. Venteicher et al. SCIENCE
- Lipid-conjugated telomerase template antagonists sensitize resistant HER2-positive breast cancer cells to trastuzumab
- (2008) Erin M. Goldblatt et al. BREAST CANCER RESEARCH AND TREATMENT
- ATM Mediates Cytotoxicity of a Mutant Telomerase RNA in Human Cancer Cells
- (2008) B. A. Stohr et al. CANCER RESEARCH
- Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly
- (2008) Andrew S. Venteicher et al. CELL
- G-Quadruplex Ligand RHPS4 Potentiates the Antitumor Activity of Camptothecins in Preclinical Models of Solid Tumors
- (2008) C. Leonetti et al. CLINICAL CANCER RESEARCH
- ssDNA fragments induce cell senescence by telomere uncapping
- (2008) Avgi Tsolou et al. EXPERIMENTAL GERONTOLOGY
- Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita
- (2008) T. Vulliamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antitumor activity of G-quadruplex–interactive agent TMPyP4 in K562 leukemic cells
- (2007) Yoko Mikami-Terao et al. CANCER LETTERS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now