Prickle1mutation causes planar cell polarity and directional cell migration defects associated with cardiac outflow tract anomalies and other structural birth defects

Role of cilia in structural birth defects: Insights from ciliopathy mutant mouse models

(2014) Rama Rao Damerla et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Scrib:Rac1 interactions are required for the morphogenesis of the ventricular myocardium

(2014) Veronika Boczonadi et al.   CARDIOVASCULAR RESEARCH

Vangl-dependent planar cell polarity signalling is not required for neural crest migration in mammals

(2014) S. E. Pryor et al.   DEVELOPMENT

The cell biology of planar cell polarity

(2014) Danelle Devenport   JOURNAL OF CELL BIOLOGY

Defective Motile Cilia inPrickle2-Deficient Mice

(2014) Levi P. Sowers et al.   JOURNAL OF NEUROGENETICS

Junctional Neurulation: A Unique Developmental Program Shaping a Discrete Region of the Spinal Cord Highly Susceptible to Neural Tube Defects

(2014) A. Dady et al.   JOURNAL OF NEUROSCIENCE

Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a

(2014) C. Liu et al.   Biology Open

Interrogating Congenital Heart Defects With Noninvasive Fetal Echocardiography in a Mouse Forward Genetic Screen

(2013) Xiaoqin Liu et al.   Circulation-Cardiovascular Imaging

Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis

(2013) Chunqiao Liu et al.   HUMAN MOLECULAR GENETICS

Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton

(2013) Cheng Cui et al.   PLOS BIOLOGY

Ex vivo Method for High Resolution Imaging of Cilia Motility in Rodent Airway Epithelia

(2013) Richard Francis et al.   Jove-Journal of Visualized Experiments

Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations

(2013) Tian Yang et al.   Molecular Genetics & Genomic Medicine

A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects

(2012) Diana M. Juriloff et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Microtubules Enable the Planar Cell Polarity of Airway Cilia

(2012) Eszter K. Vladar et al.   CURRENT BIOLOGY

Wnt5a and Wnt11 are essential for second heart field progenitor development

(2012) E. D. Cohen et al.   DEVELOPMENT

Disheveled mediated planar cell polarity signaling is required in the second heart field lineage for outflow tract morphogenesis

(2012) Tanvi Sinha et al.   DEVELOPMENTAL BIOLOGY

Branched F-actin as a negative regulator of cilia formation

(2012) Xiumin Yan et al.   EXPERIMENTAL CELL RESEARCH

Predicting the Functional Effect of Amino Acid Substitutions and Indels

(2012) Yongwook Choi et al.   PLoS One

Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans

(2011) Hirotaka Tao et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Disruption of planar cell polarity activity leads to developmental biliary defects

(2011) Shuang Cui et al.   DEVELOPMENTAL BIOLOGY

The planar cell polarity pathway in vertebrate development

(2011) Carolien Wansleeben et al.   DEVELOPMENTAL DYNAMICS

Robinow syndrome: report of two patients and review of literature

(2010) Merlin G. Butler et al.   CLINICAL GENETICS

Molecular mechanisms of cranial neural crest cell migration and patterning in craniofacial development

(2010) M. Minoux et al.   DEVELOPMENT

Broad-Minded Links Cell Cycle-Related Kinase to Cilia Assembly and Hedgehog Signal Transduction

(2010) Hyuk Wan Ko et al.   DEVELOPMENTAL CELL

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

(2010) Laura L. Yates et al.   HUMAN MOLECULAR GENETICS

PKC  regulates cell polarisation and proliferation restriction during mammary acinus formation

(2010) J. Whyte et al.   JOURNAL OF CELL SCIENCE

Functional genomic screen for modulators of ciliogenesis and cilium length

(2010) Joon Kim et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Wnt signaling pathways meet Rho GTPases

(2009) K. Schlessinger et al.   GENES & DEVELOPMENT

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity

(2009) H. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Progress and challenges in understanding planar cell polarity signaling

(2009) Jeffrey D. Axelrod   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Planar Cell Polarity Signaling: The Developing Cell's Compass

(2009) E. K. Vladar et al.   Cold Spring Harbor Perspectives in Biology

A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-Recessive Progressive Myoclonus Epilepsy-Ataxia Syndrome

(2008) Alexander G. Bassuk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

β-Catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development

(2008) Xinping Tan et al.   HEPATOLOGY

Cilia put a brake on Wnt signalling

(2008) Xi He   NATURE CELL BIOLOGY

Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development

(2008) S. Leah Etheridge et al.   PLoS Genetics

Polarity complex proteins

(2007) Emeline Assémat et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES