Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations

Prickle1 stunts limb growth through alteration of cell polarity and gene expression

(2013) Tian Yang et al.   DEVELOPMENTAL DYNAMICS

Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers

(2013) C. Attanasio et al.   SCIENCE

Resequencing ofVAX1in patients with nonsyndromic cleft lip with or without cleft palate

(2012) Entessar Nasser et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Association ofDVL2andAXIN2gene polymorphisms with cleft lip with or without cleft palate in a polish population

(2012) Adrianna Mostowska et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes

(2012) H. Yu et al.   DEVELOPMENT

The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled

(2012) Derrick M. Glasco et al.   DEVELOPMENTAL BIOLOGY

Genotype and haplotype analysis of WNT genes in non-syndromic cleft lip with or without cleft palate

(2012) Adrianna Mostowska et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

(2012) Kerstin U Ludwig et al.   NATURE GENETICS

Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans

(2011) Hirotaka Tao et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity

(2011) O. M. Mapp et al.   DEVELOPMENT

Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development

(2011) J. O. Bush et al.   DEVELOPMENT

Wnt Signaling Gradients Establish Planar Cell Polarity by Inducing Vangl2 Phosphorylation through Ror2

(2011) Bo Gao et al.   DEVELOPMENTAL CELL

No evidence for a role of CRISPLD2 in non-syndromic cleft lip with or without cleft palate in an Italian population

(2011) Ambra Girardi et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Cleft lip and palate: understanding genetic and environmental influences

(2011) Michael J. Dixon et al.   NATURE REVIEWS GENETICS

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

(2010) William McLaren et al.   BIOINFORMATICS

Studies with Wnt genes and nonsyndromic cleft lip and palate

(2010) Renato Menezes et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes

(2010) H. Yu et al.   DEVELOPMENT

Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B

(2010) Bing Wang et al.   HUMAN MOLECULAR GENETICS

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4

(2010) Terri H Beaty et al.   NATURE GENETICS

When pathways collide: collaboration and connivance among signalling proteins in development

(2010) Helen McNeill et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Signaling integration in the rugae growth zone directs sequential SHH signaling center formation during the rostral outgrowth of the palate

(2009) Ian C. Welsh et al.   DEVELOPMENTAL BIOLOGY

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity

(2009) H. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-Recessive Progressive Myoclonus Epilepsy-Ataxia Syndrome

(2008) Alexander G. Bassuk et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Review on genetic variants and maternal smoking in the etiology of oral clefts and other birth defects

(2008) Min Shi et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development

(2008) Sophie Pantalacci et al.   BMC DEVELOPMENTAL BIOLOGY

The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome

(2008) R. Raz et al.   DEVELOPMENT

Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development

(2008) F. He et al.   DEVELOPMENT

Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate

(2008) Brett T. Chiquet et al.   HUMAN MOLECULAR GENETICS

Phenotypic variability and craniofacial dysmorphology: increased shape variance in a mouse model for cleft lip

(2008) Trish E. Parsons et al.   JOURNAL OF ANATOMY

GPS 2.0, a Tool to Predict Kinase-specific Phosphorylation Sites in Hierarchy

(2008) Yu Xue et al.   MOLECULAR & CELLULAR PROTEOMICS

From individual Wnt pathways towards a Wnt signalling network

(2008) H. A Kestler et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Genetic interaction between members of the Vangl family causes neural tube defects in mice

(2008) E. Torban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA