Defective Motile Cilia inPrickle2-Deficient Mice

Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis

(2013) Chunqiao Liu et al.   HUMAN MOLECULAR GENETICS

The non-canonical Wnt ligand Wnt5a rescues morphological deficits in Prickle2-deficient hippocampal neurons

(2013) L P Sowers et al.   MOLECULAR PSYCHIATRY

Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction

(2013) L P Sowers et al.   MOLECULAR PSYCHIATRY

Microtubules Enable the Planar Cell Polarity of Airway Cilia

(2012) Eszter K. Vladar et al.   CURRENT BIOLOGY

Nuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesis

(2012) Hirotaka Tao et al.   DEVELOPMENTAL BIOLOGY

Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans

(2011) Hirotaka Tao et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prickle2 is localized in the postsynaptic density and interacts with PSD-95 and NMDA receptors in the brain

(2011) Y. Hida et al.   JOURNAL OF BIOCHEMISTRY

Planar cell polarity signaling, cilia and polarized ciliary beating

(2010) John B Wallingford   CURRENT OPINION IN CELL BIOLOGY

Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II

(2010) Y. Hirota et al.   DEVELOPMENT

Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ

(2010) P. Oteiza et al.   DEVELOPMENT

Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia

(2010) Boris Guirao et al.   NATURE CELL BIOLOGY

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

(2010) Fadel Tissir et al.   NATURE NEUROSCIENCE

Planar Cell Polarity Enables Posterior Localization of Nodal Cilia and Left-Right Axis Determination during Mouse and Xenopus Embryogenesis

(2010) Dragana Antic et al.   PLoS One

The PCP Pathway Instructs the Planar Orientation of Ciliated Cells in the Xenopus Larval Skin

(2009) Brian Mitchell et al.   CURRENT BIOLOGY

Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility

(2009) Toshimitsu Suzuki et al.   HUMAN MOLECULAR GENETICS

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity

(2009) H. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

(2008) Tae Joo Park et al.   NATURE GENETICS