Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPases

Actin Out: Regulation of the Synaptic Cytoskeleton

(2015) Erin F. Spence et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impermanence of dendritic spines in live adult CA1 hippocampus

(2015) Alessio Attardo et al.   NATURE

Rapid Dispersion of SynGAP from Synaptic Spines Triggers AMPA Receptor Insertion and Spine Enlargement during LTP

(2015) Yoichi Araki et al.   NEURON

PICK1 links AMPA receptor stimulation to Cdc42

(2015) Daniel L. Rocca et al.   NEUROSCIENCE LETTERS

Mechanisms for spatiotemporal regulation of Rho-GTPase signaling at synapses

(2015) Joseph G. Duman et al.   NEUROSCIENCE LETTERS

Rapid modulation of synaptogenesis and spinogenesis by 17β-estradiol in primary cortical neurons

(2015) Katherine J. Sellers et al.   Frontiers in Cellular Neuroscience

Palmitoylation of LIM Kinase-1 ensures spine-specific actin polymerization and morphological plasticity

(2015) Joju George et al.   eLife

Coordinated Nuclear and Synaptic Shuttling of Afadin Promotes Spine Plasticity and Histone Modifications

(2014) Jon-Eric VanLeeuwen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long-Term In Vivo Imaging of Dendritic Spines in the Hippocampus Reveals Structural Plasticity

(2014) L. Gu et al.   JOURNAL OF NEUROSCIENCE

Spine neck plasticity regulates compartmentalization of synapses

(2014) Jan Tønnesen et al.   NATURE NEUROSCIENCE

Structural and Molecular Remodeling of Dendritic Spine Substructures during Long-Term Potentiation

(2014) Miquel Bosch et al.   NEURON

Regulation of the Mouse Medial Prefrontal Cortical Synapses by Endogenous Estradiol

(2014) Christopher Galvin et al.   NEUROPSYCHOPHARMACOLOGY

Dendritic Spines: The Locus of Structural and Functional Plasticity

(2014) Carlo Sala et al.   PHYSIOLOGICAL REVIEWS

Structural plasticity: mechanisms and contribution to developmental psychiatric disorders

(2014) Yann Bernardinelli et al.   Frontiers in Neuroanatomy

Plasticity of Dendritic Spines: Subcompartmentalization of Signaling

(2013) Lesley A. Colgan et al.   Annual Review of Physiology

Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders

(2013) Peter Penzes et al.   JOURNAL OF NEUROCHEMISTRY

Rapid Effects of Oestrogen on Synaptic Plasticity: Interactions with Actin and Its Signalling Proteins

(2013) A. H. Babayan et al.   JOURNAL OF NEUROENDOCRINOLOGY

Identification of a Novel Prenyl and Palmitoyl Modification at the CaaX Motif of Cdc42 That Regulates RhoGDI Binding

(2013) A. Nishimura et al.   MOLECULAR AND CELLULAR BIOLOGY

Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance

(2013) Conor Liston et al.   NATURE NEUROSCIENCE

The Neurobiology of X-Linked Intellectual Disability

(2013) Silvia Bassani et al.   NEUROSCIENTIST

Regulation of Small GTPases by GEFs, GAPs, and GDIs

(2013) Jacqueline Cherfils et al.   PHYSIOLOGICAL REVIEWS

Pathogenic SYNGAP1 Mutations Impair Cognitive Development by Disrupting Maturation of Dendritic Spine Synapses

(2012) James P. Clement et al.   CELL

Deconstructing signal transduction pathways that regulate the actin cytoskeleton in dendritic spines

(2012) Peter Penzes et al.   Cytoskeleton

The Ca2+ and Rho GTPase signaling pathways underlying activity-dependent actin remodeling at dendritic spines

(2012) Takeo Saneyoshi et al.   Cytoskeleton

Afadin Is Required for Maintenance of Dendritic Structure and Excitatory Tone

(2012) Deepak P. Srivastava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subsynaptic AMPA Receptor Distribution Is Acutely Regulated by Actin-Driven Reorganization of the Postsynaptic Density

(2012) J. M. Kerr et al.   JOURNAL OF NEUROSCIENCE

Social, Communication, and Cortical Structural Impairments in Epac2-Deficient Mice

(2012) D. P. Srivastava et al.   JOURNAL OF NEUROSCIENCE

Postsynaptic signaling during plasticity of dendritic spines

(2012) Hideji Murakoshi et al.   TRENDS IN NEUROSCIENCES

An Autism-Associated Variant of Epac2 Reveals a Role for Ras/Epac2 Signaling in Controlling Basal Dendrite Maintenance in Mice

(2012) Deepak P. Srivastava et al.   PLOS BIOLOGY

De Novo SYNGAP1 Mutations in Nonsyndromic Intellectual Disability and Autism

(2011) Fadi F. Hamdan et al.   BIOLOGICAL PSYCHIATRY

PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity

(2011) Yasuko Nakamura et al.   EMBO JOURNAL

Activation of Rho GTPases Triggers Structural Remodeling and Functional Plasticity in the Adult Rat Visual Cortex

(2011) C. Cerri et al.   JOURNAL OF NEUROSCIENCE

Rapid Estrogen Signaling in the Brain: Implications for the Fine-Tuning of Neuronal Circuitry

(2011) D. P. Srivastava et al.   JOURNAL OF NEUROSCIENCE

In vivotwo-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice

(2011) Jun Noguchi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Glutamate induces de novo growth of functional spines in developing cortex

(2011) Hyung-Bae Kwon et al.   NATURE

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Requirement for Plk2 in Orchestrated Ras and Rap Signaling, Homeostatic Structural Plasticity, and Memory

(2011) Kea Joo Lee et al.   NEURON

Dendritic Spines and Distributed Circuits

(2011) Rafael Yuste   NEURON

Experience-dependent structural plasticity in the cortex

(2011) Min Fu et al.   TRENDS IN NEUROSCIENCES

Synapse Pathology in Psychiatric and Neurologic Disease

(2010) Myrrhe van Spronsen et al.   Current Neurology and Neuroscience Reports

Neuronal structural remodeling: is it all about access?

(2010) Jerry L Chen et al.   CURRENT OPINION IN NEUROBIOLOGY

Kalirin-7, an important component of excitatory synapses, is regulated by estradiol in hippocampal neurons

(2010) Xin-Ming Ma et al.   HIPPOCAMPUS

A Hypothesized Role for Dendritic Remodeling in the Etiology of Mood and Anxiety Disorders

(2010) J. M. Gorman et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Estrogen Receptor   Activity Modulates Synaptic Signaling and Structure

(2010) D. P. Srivastava et al.   JOURNAL OF NEUROSCIENCE

Structural Dynamics of Synapses in Vivo Correlate with Functional Changes during Experience-Dependent Plasticity in Visual Cortex

(2010) D. Tropea et al.   JOURNAL OF NEUROSCIENCE

p21-Activated Kinases 1 and 3 Control Brain Size through Coordinating Neuronal Complexity and Synaptic Properties

(2010) W. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Epac2-mediated dendritic spine remodeling: Implications for disease

(2010) Peter Penzes et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity

(2010) Jiaping Gu et al.   NATURE NEUROSCIENCE

Protein palmitoylation in neuronal development and synaptic plasticity

(2010) Yuko Fukata et al.   NATURE REVIEWS NEUROSCIENCE

Small G Protein Signaling in Neuronal Plasticity and Memory Formation: The Specific Role of Ras Family Proteins

(2010) Xiaojing Ye et al.   NEURON

Single-Molecule Discrimination of Discrete Perisynaptic and Distributed Sites of Actin Filament Assembly within Dendritic Spines

(2010) Nicholas A. Frost et al.   NEURON

Structural dynamics of dendritic spines in memory and cognition

(2010) Haruo Kasai et al.   TRENDS IN NEUROSCIENCES

Dendritic Spine Dynamics

(2009) D. Harshad Bhatt et al.   Annual Review of Physiology

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

(2009) Jeffrey J. Hutsler et al.   BRAIN RESEARCH

Cofilin Dissociates Arp2/3 Complex and Branches from Actin Filaments

(2009) Chikio Chan et al.   CURRENT BIOLOGY

Dendritic spine formation and stabilization

(2009) Yoshihiro Yoshihara et al.   CURRENT OPINION IN NEUROBIOLOGY

The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors

(2009) N. Nadif Kasri et al.   GENES & DEVELOPMENT

Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis

(2009) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies

(2009) David A. Lewis et al.   JOURNAL OF CLINICAL INVESTIGATION

Focal Adhesion Kinase Acts Downstream of EphB Receptors to Maintain Mature Dendritic Spines by Regulating Cofilin Activity

(2009) Y. Shi et al.   JOURNAL OF NEUROSCIENCE

Rapid Signaling of Estrogen to WAVE1 and Moesin Controls Neuronal Spine Formation via the Actin Cytoskeleton

(2009) Angel Matias Sanchez et al.   MOLECULAR ENDOCRINOLOGY

Stably maintained dendritic spines are associated with lifelong memories

(2009) Guang Yang et al.   NATURE

Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines

(2009) Kevin M Woolfrey et al.   NATURE NEUROSCIENCE

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

Normal Development of Brain Circuits

(2009) Gregory Z Tau et al.   NEUROPSYCHOPHARMACOLOGY

Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes

(2009) M. E. Cahill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPA receptor and GEF-H1/Lfc complex regulates dendritic spine development through RhoA signaling cascade

(2009) M.-G. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling

(2009) K. A. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biphasic Synaptic Ca Influx Arising from Compartmentalized Electrical Signals in Dendritic Spines

(2009) Brenda L. Bloodgood et al.   PLOS BIOLOGY

Rap2 function requires palmitoylation and recycling endosome localization

(2008) Yukiko Uechi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

N-WASP and the Arp2/3 Complex Are Critical Regulators of Actin in the Development of Dendritic Spines and Synapses

(2008) Adam M. Wegner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of Synaptic Adhesion with Dendritic Spine Remodeling by AF-6 and Kalirin-7

(2008) Z. Xie et al.   JOURNAL OF NEUROSCIENCE

Constitutively Active Rap2 Transgenic Mice Display Fewer Dendritic Spines, Reduced Extracellular Signal-Regulated Kinase Signaling, Enhanced Long-Term Depression, and Impaired Spatial Learning and Fear Extinction

(2008) J. Ryu et al.   JOURNAL OF NEUROSCIENCE

SynGAP Regulates Steady-State and Activity-Dependent Phosphorylation of Cofilin

(2008) H. J. Carlisle et al.   JOURNAL OF NEUROSCIENCE

Evolutionary expansion and anatomical specialization of synapse proteome complexity

(2008) Richard D Emes et al.   NATURE NEUROSCIENCE

A critical role of Rho-kinase ROCK2 in the regulation of spine and synaptic function

(2008) Zikai Zhou et al.   NEUROPHARMACOLOGY

Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1)

(2008) Suhail Asrar et al.   NEUROPHARMACOLOGY

Rapid enhancement of two-step wiring plasticity by estrogen and NMDA receptor activity

(2008) D. P. Srivastava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Spread of Ras Activity Triggered by Activation of a Single Dendritic Spine

(2008) C. D. Harvey et al.   SCIENCE

Convergent CaMK and RacGEF signals control dendritic structure and function

(2008) Peter Penzes et al.   TRENDS IN CELL BIOLOGY