Actin Out: Regulation of the Synaptic Cytoskeleton

Dynamic Visualization of α-Catenin Reveals Rapid, Reversible Conformation Switching between Tension States

(2015) Tae-Jin Kim et al.   CURRENT BIOLOGY

PICK1 is implicated in organelle motility in an Arp2/3 complex–independent manner

(2015) Yadaiah Madasu et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanical coupling between transsynaptic N-cadherin adhesions and actin flow stabilizes dendritic spines

(2015) Anaël Chazeau et al.   MOLECULAR BIOLOGY OF THE CELL

Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine

(2015) Il Hwan Kim et al.   NATURE NEUROSCIENCE

Biallelic Truncating Mutations in FMN2, Encoding the Actin-Regulatory Protein Formin 2, Cause Nonsyndromic Autosomal-Recessive Intellectual Disability

(2014) Rosalind Law et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton

(2014) Baoyu Chen et al.   CELL

Nanoscale segregation of actin nucleation and elongation factors determines dendritic spine protrusion

(2014) Anaël Chazeau et al.   EMBO JOURNAL

Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N

(2014) L. N. Munsie et al.   HUMAN MOLECULAR GENETICS

Protein Interacting with C-kinase 1 (PICK1) Binding Promiscuity Relies on Unconventional PSD-95/Discs-Large/ZO-1 Homology (PDZ) Binding Modes for Nonclass II PDZ Ligands

(2014) Simon Erlendsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features

(2014) Valter Tucci et al.   JOURNAL OF CLINICAL INVESTIGATION

The X-linked Mental Retardation Protein OPHN1 Interacts with Homer1b/c to Control Spine Endocytic Zone Positioning and Expression of Synaptic Potentiation

(2014) A. Nakano-Kobayashi et al.   JOURNAL OF NEUROSCIENCE

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

Spine neck plasticity regulates compartmentalization of synapses

(2014) Jan Tønnesen et al.   NATURE NEUROSCIENCE

Capping protein regulators fine-tune actin assembly dynamics

(2014) Marc Edwards et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and Molecular Remodeling of Dendritic Spine Substructures during Long-Term Potentiation

(2014) Miquel Bosch et al.   NEURON

Retromer Mediates a Discrete Route of Local Membrane Delivery to Dendrites

(2014) Regina Wai-Yan Choy et al.   NEURON

Activity-Dependent Dendritic Spine Shrinkage and Growth Involve Downregulation of Cofilin via Distinct Mechanisms

(2014) Barbara Calabrese et al.   PLoS One

A Septin-Dependent Diffusion Barrier at Dendritic Spine Necks

(2014) Helge Ewers et al.   PLoS One

Actin-dependent mechanisms in AMPA receptor trafficking

(2014) Jonathan G. Hanley   Frontiers in Cellular Neuroscience

A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness

(2014) Theron A. Russell et al.   Nature Communications

Loss of Cdc42 leads to defects in synaptic plasticity and remote memory recall

(2014) Il Hwan Kim et al.   eLife

Electrical Compartmentalization in Dendritic Spines

(2013) Rafael Yuste   Annual Review of Neuroscience

Eps8 controls dendritic spine density and synaptic plasticity through its actin-capping activity

(2013) Elisabetta Menna et al.   EMBO JOURNAL

Disruption of Arp2/3 Results in Asymmetric Structural Plasticity of Dendritic Spines and Progressive Synaptic and Behavioral Abnormalities

(2013) I. H. Kim et al.   JOURNAL OF NEUROSCIENCE

AMPARs and Synaptic Plasticity: The Last 25 Years

(2013) Richard L. Huganir et al.   NEURON

Ultrastructural Abnormalities in CA1 Hippocampus Caused by Deletion of the Actin Regulator WAVE-1

(2013) Diána Hazai et al.   PLoS One

Under lock and key: Spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processes

(2013) Lauren E. Burianek et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Afadin Is Required for Maintenance of Dendritic Structure and Excitatory Tone

(2012) Deepak P. Srivastava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subsynaptic AMPA Receptor Distribution Is Acutely Regulated by Actin-Driven Reorganization of the Postsynaptic Density

(2012) J. M. Kerr et al.   JOURNAL OF NEUROSCIENCE

New insights into the regulation and cellular functions of the ARP2/3 complex

(2012) Jeremy D. Rotty et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cofilin-1: A Modulator of Anxiety in Mice

(2012) Martin Goodson et al.   PLoS Genetics

Identification of a novel candidate gene for non-syndromic autosomal recessive intellectual disability: the WASH complex member SWIP

(2011) F. Ropers et al.   HUMAN MOLECULAR GENETICS

Actin Capping Protein Is Required for Dendritic Spine Development and Synapse Formation

(2011) Y. Fan et al.   JOURNAL OF NEUROSCIENCE

WRP/srGAP3 Facilitates the Initiation of Spine Development by an Inverse F-BAR Domain, and Its Loss Impairs Long-Term Memory

(2011) B. R. Carlson et al.   JOURNAL OF NEUROSCIENCE

GluA2 (GluR2) Regulates Metabotropic Glutamate Receptor-Dependent Long-Term Depression through N-Cadherin-Dependent and Cofilin-Mediated Actin Reorganization

(2011) Z. Zhou et al.   JOURNAL OF NEUROSCIENCE

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Control of synapse development and plasticity by Rho GTPase regulatory proteins

(2011) Kimberley F. Tolias et al.   PROGRESS IN NEUROBIOLOGY

Control of Actin Filament Treadmilling in Cell Motility

(2010) Beáta Bugyi et al.   Annual Review of Biophysics

Adhesion properties and retinofugal expression of chicken protocadherin-19

(2010) Kiyoto Tai et al.   BRAIN RESEARCH

Sequence-Dependent Sorting of Recycling Proteins by Actin-Stabilized Endosomal Microdomains

(2010) Manojkumar A. Puthenveedu et al.   CELL

Synapse Pathology in Psychiatric and Neurologic Disease

(2010) Myrrhe van Spronsen et al.   Current Neurology and Neuroscience Reports

Learning, AMPA receptor mobility and synaptic plasticity depend on n-cofilin-mediated actin dynamics

(2010) Marco B Rust et al.   EMBO JOURNAL

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

(2010) M. E. Harbour et al.   JOURNAL OF CELL SCIENCE

A three-step model for the synaptic recruitment of AMPA receptors

(2010) Patricio Opazo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity

(2010) Jiaping Gu et al.   NATURE NEUROSCIENCE

Single-Molecule Discrimination of Discrete Perisynaptic and Distributed Sites of Actin Filament Assembly within Dendritic Spines

(2010) Nicholas A. Frost et al.   NEURON

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

The Arp2/3 Activator WASH Controls the Fission of Endosomes through a Large Multiprotein Complex

(2009) Emmanuel Derivery et al.   DEVELOPMENTAL CELL

The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors

(2009) N. Nadif Kasri et al.   GENES & DEVELOPMENT

Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis

(2009) Pirta Hotulainen et al.   JOURNAL OF CELL BIOLOGY

Kinase-Dead Knock-In Mouse Reveals an Essential Role of Kinase Activity of Ca2+/Calmodulin-Dependent Protein Kinase II  in Dendritic Spine Enlargement, Long-Term Potentiation, and Learning

(2009) Y. Yamagata et al.   JOURNAL OF NEUROSCIENCE

Molecular Architecture of Synaptic Actin Cytoskeleton in Hippocampal Neurons Reveals a Mechanism of Dendritic Spine Morphogenesis

(2009) Farida Korobova et al.   MOLECULAR BIOLOGY OF THE CELL

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

Contact-dependent promotion of cell migration by the OL-protocadherin–Nap1 interaction

(2008) Shinsuke Nakao et al.   JOURNAL OF CELL BIOLOGY

Coordination of Synaptic Adhesion with Dendritic Spine Remodeling by AF-6 and Kalirin-7

(2008) Z. Xie et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Arp2/3-mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis

(2008) Daniel L. Rocca et al.   NATURE CELL BIOLOGY

The Subspine Organization of Actin Fibers Regulates the Structure and Plasticity of Dendritic Spines

(2008) Naoki Honkura et al.   NEURON