Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection

Targets and Mechanisms Associated with Protection from Severe Plasmodium falciparum Malaria in Kenyan Children

(2016) Linda M. Murungi et al.   INFECTION AND IMMUNITY

Demonstration of the Blood-StagePlasmodium falciparumControlled Human Malaria Infection Model to Assess Efficacy of theP. falciparumApical Membrane Antigen 1 Vaccine, FMP2.1/AS01

(2016) Ruth O. Payne et al.   JOURNAL OF INFECTIOUS DISEASES

Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection

(2015) Kirsten E. Lyke et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A PfRH5-Based Vaccine Is Efficacious against Heterologous Strain Blood-Stage Plasmodium falciparum Infection in Aotus Monkeys

(2015) Alexander D. Douglas et al.   Cell Host & Microbe

Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

(2015) Gloria P Gómez-Pérez et al.   MALARIA JOURNAL

Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya

(2015) Susanne H Hodgson et al.   MALARIA JOURNAL

Standardization of the antibody-dependent respiratory burst assay with human neutrophils and Plasmodium falciparum malaria

(2015) David Llewellyn et al.   Scientific Reports

Controlled Human Malaria Infection of Tanzanians by Intradermal Injection of Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites

(2014) Seif Shekalaghe et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Assessment of the neutrophilic antibody-dependent respiratory burst (ADRB) response to Plasmodium falciparum

(2014) Stephanie Kapelski et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Assessment of Humoral Immune Responses to Blood-Stage Malaria Antigens following ChAd63-MVA Immunization, Controlled Human Malaria Infection and Natural Exposure

(2014) Sumi Biswas et al.   PLoS One

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection

(2014) Susanne H. Hodgson et al.   Frontiers in Microbiology

Taking a Bite out of Malaria: Controlled Human Malaria Infection by Needle and Syringe

(2013) Judith E. Epstein   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Breadth of Anti-Merozoite Antibody Responses Is Associated With the Genetic Diversity of Asymptomatic Plasmodium falciparum Infections and Protection Against Clinical Malaria

(2013) Josea Rono et al.   CLINICAL INFECTIOUS DISEASES

Analysis of human B-cell responses following ChAd63-MVA MSP1 and AMA1 immunization and controlled malaria infection

(2013) Sean C. Elias et al.   IMMUNOLOGY

Naturally Acquired Antibodies Specific for Plasmodium falciparum Reticulocyte-Binding Protein Homologue 5 Inhibit Parasite Growth and Predict Protection From Malaria

(2013) Tuan M. Tran et al.   JOURNAL OF INFECTIOUS DISEASES

Comparison of Modeling Methods to Determine Liver-to-blood Inocula and Parasite Multiplication Rates During Controlled Human Malaria Infection

(2013) Alexander D. Douglas et al.   JOURNAL OF INFECTIOUS DISEASES

Assessment of antibody-dependent respiratory burst activity from mouse neutrophils on Plasmodium yoelii malaria challenge outcome

(2013) David Llewellyn et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe

(2013) Susanne H. Sheehy et al.   PLoS One

A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria

(2013) Linda M. Murungi et al.   VACCINE

Challenges of assessing the clinical efficacy of asexual blood-stagePlasmodium falciparummalaria vaccines

(2013) Susanne H Sheehy et al.   Human Vaccines & Immunotherapeutics

Controlled Human Blood Stage Malaria Infection: Current Status and Potential Applications

(2012) Christopher J. A. Duncan et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites

(2012) Meta Roestenberg et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Efficacy of Preerythrocytic and Blood-Stage Malaria Vaccines Can Be Assessed in Small Sporozoite Challenge Trials in Human Volunteers

(2012) M. Roestenberg et al.   JOURNAL OF INFECTIOUS DISEASES

Anti-Plasmodium falciparum invasion ligand antibodies in a low malaria transmission region, Loreto, Peru

(2012) Elizabeth Villasis et al.   MALARIA JOURNAL

ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans

(2012) Susanne H Sheehy et al.   MOLECULAR THERAPY

Phase Ia Clinical Evaluation of the Safety and Immunogenicity of the Plasmodium falciparum Blood-Stage Antigen AMA1 in ChAd63 and MVA Vaccine Vectors

(2012) Susanne H. Sheehy et al.   PLoS One

Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children

(2012) F. M. Ndungu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy?

(2012) Christopher J.A. Duncan et al.   Human Vaccines & Immunotherapeutics

Impact on Malaria Parasite Multiplication Rates in Infected Volunteers of the Protein-in-Adjuvant Vaccine AMA1-C1/Alhydrogel+CPG 7909

(2011) Christopher J. A. Duncan et al.   PLoS One

A Pilot Randomised Trial of Induced Blood-Stage Plasmodium falciparum Infections in Healthy Volunteers for Testing Efficacy of New Antimalarial Drugs

(2011) James S. McCarthy et al.   PLoS One

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

(2011) Alexander D. Douglas et al.   Nature Communications

Clinical Protection from Falciparum Malaria Correlates with Neutrophil Respiratory Bursts Induced by Merozoites Opsonized with Human Serum Antibodies

(2010) Charlotte Joos et al.   PLoS One

Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

(2007) Kazutoyo Miura et al.   VACCINE