Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy?

Comparison of Biological Activity of Human Anti-Apical Membrane Antigen-1 Antibodies Induced by Natural Infection and Vaccination

(2014) K. Miura et al.   JOURNAL OF IMMUNOLOGY

Controlled Human Blood Stage Malaria Infection: Current Status and Potential Applications

(2012) Christopher J. A. Duncan et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Blood stage vaccines forPlasmodium falciparum

(2011) Ruth D. Ellis et al.   Human vaccines & immunotherapeutics

Substantially Reduced Pre-patent Parasite Multiplication Rates Are Associated With Naturally Acquired Immunity to Plasmodium falciparum

(2011) A. D. Douglas et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of the Pre-erythrocytic Candidate Malaria Vaccine RTS,S/AS01E on Blood Stage Immunity in Young Children

(2011) Philip Bejon et al.   JOURNAL OF INFECTIOUS DISEASES

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

(2011) Meta Roestenberg et al.   LANCET

Safety and efficacy of the RTS,S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

(2011) Kwaku Poku Asante et al.   LANCET INFECTIOUS DISEASES

Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a randomised controlled trial

(2011) Ally Olotu et al.   LANCET INFECTIOUS DISEASES

Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study

(2011) Jean-François Trape et al.   LANCET INFECTIOUS DISEASES

Malaria infection by sporozoite challenge induces high functional antibody titres against blood stage antigens after a DNA prime, poxvirus boost vaccination strategy in Rhesus macaques

(2011) Muzamil Mahdi Abdel Hamid et al.   MALARIA JOURNAL

Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors

(2011) Susanne H Sheehy et al.   MOLECULAR THERAPY

A Field Trial to Assess a Blood-Stage Malaria Vaccine

(2011) Mahamadou A. Thera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vaccines against malaria

(2011) A. V. S. Hill   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Vaccination with Plasmodium knowlesi AMA1 Formulated in the Novel Adjuvant Co-Vaccine HT™ Protects against Blood-Stage Challenge in Rhesus Macaques

(2011) Muzamil Mahdi Abdel Hamid et al.   PLoS One

Non-Apical Membrane Antigen 1 (AMA1) IgGs from Malian Children Interfere with Functional Activity of AMA1 IgGs as Judged by Growth Inhibition Assay

(2011) Kazutoyo Miura et al.   PLoS One

Impact on Malaria Parasite Multiplication Rates in Infected Volunteers of the Protein-in-Adjuvant Vaccine AMA1-C1/Alhydrogel+CPG 7909

(2011) Christopher J. A. Duncan et al.   PLoS One

Quantifying the Importance of MSP1-19 as a Target of Growth-Inhibitory and Protective Antibodies against Plasmodium falciparum in Humans

(2011) Danny W. Wilson et al.   PLoS One

Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized

(2011) Kazutoyo Miura et al.   VACCINE

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

(2011) Alexander D. Douglas et al.   Nature Communications

Blood-stage malaria vaccines — recent progress and future challenges

(2010) A. L. Goodman et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Recombinant protein vaccines against the asexual blood-stages ofPlasmodium falciparum

(2010) Robin F. Anders et al.   Human vaccines & immunotherapeutics

Development of a metabolically active, non-replicating sporozoite vaccine to preventPlasmodium falciparummalaria

(2010) Stephen L. Hoffman et al.   Human vaccines & immunotherapeutics

Prime-boost vectored malaria vaccines: Progress and prospects

(2010) Adrian V. S. Hill et al.   Human vaccines & immunotherapeutics

Advances and challenges in malaria vaccine development

(2010) Peter D. Crompton et al.   JOURNAL OF CLINICAL INVESTIGATION

Development of fluorescent Plasmodium falciparum for in vitro growth inhibition assays

(2010) Danny W Wilson et al.   MALARIA JOURNAL

Clinical Protection from Falciparum Malaria Correlates with Neutrophil Respiratory Bursts Induced by Merozoites Opsonized with Human Serum Antibodies

(2010) Charlotte Joos et al.   PLoS One

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

(2010) M. J. Boyle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

(2010) Freya J. I. Fowkes et al.   PLOS MEDICINE

The Plasmodium falciparum-Specific Human Memory B Cell Compartment Expands Gradually with Repeated Malaria Infections

(2010) Greta E. Weiss et al.   PLoS Pathogens

Erythrocyte invasion and functionally inhibitory antibodies in Plasmodium falciparum malaria

(2009) Kristina E.M. Persson   ACTA TROPICA

Anti-Apical-Membrane-Antigen-1 Antibody Is More Effective than Anti-42-Kilodalton-Merozoite-Surface-Protein-1 Antibody in Inhibiting Plasmodium falciparum Growth, as Determined by the In Vitro Growth Inhibition Assay

(2009) K. Miura et al.   Clinical and Vaccine Immunology

Inhibitory Antibodies Specific for the 19-Kilodalton Fragment of Merozoite Surface Protein 1 Do Not Correlate with Delayed Appearance of Infection with Plasmodium falciparum in Semi-Immune Individuals in Vietnam

(2009) E. E. H. Murhandarwati et al.   INFECTION AND IMMUNITY

In Vitro Growth-Inhibitory Activity and Malaria Risk in a Cohort Study in Mali

(2009) P. D. Crompton et al.   INFECTION AND IMMUNITY

Analysis of Immunity to Febrile Malaria in Children That Distinguishes Immunity from Lack of Exposure

(2009) P. Bejon et al.   INFECTION AND IMMUNITY

The Potential Role of Vaccines in the Elimination of Falciparum Malaria and the Eventual Eradication of Malaria

(2009) Christopher V. Plowe et al.   JOURNAL OF INFECTIOUS DISEASES

Age patterns of severe paediatric malaria and their relationship to Plasmodium falciparum transmission intensity

(2009) Emelda A Okiro et al.   MALARIA JOURNAL

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protection against a Malaria Challenge by Sporozoite Inoculation

(2009) Meta Roestenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria

(2009) A. A. HOLDER   PARASITOLOGY

Blood Stage Malaria Vaccine Eliciting High Antigen-Specific Antibody Concentrations Confers No Protection to Young Children in Western Kenya

(2009) Bernhards R. Ogutu et al.   PLoS One

Phase 1/2a Study of the Malaria Vaccine Candidate Apical Membrane Antigen-1 (AMA-1) Administered in Adjuvant System AS01B or AS02A

(2009) Michele D. Spring et al.   PLoS One

The Quantity and Quality of African Children's IgG Responses to Merozoite Surface Antigens Reflect Protection against Plasmodium falciparum Malaria

(2009) David Courtin et al.   PLoS One

High Antibody Titer against Apical Membrane Antigen-1 Is Required to Protect against Malaria in the Aotus Model

(2009) Sheetij Dutta et al.   PLoS One

Interactions between Age and ITN Use Determine the Risk of Febrile Malaria in Children

(2009) Philip Bejon et al.   PLoS One

Report of a Consultation on the Optimization of Clinical Challenge Trials for Evaluation of Candidate Blood Stage Malaria Vaccines, 18–19 March 2009, Bethesda, MD, USA

(2009) V.S. Moorthy et al.   VACCINE

A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali

(2009) Issaka Sagara et al.   VACCINE

A Distinct Peripheral Blood Monocyte Phenotype Is Associated with Parasite Inhibitory Activity in Acute Uncomplicated Plasmodium falciparum Malaria

(2009) Pattamawan Chimma et al.   PLoS Pathogens

Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites

(2008) Paul R. Gilson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Acquisition of Invasion‐Inhibitory Antibodies Specific for the 19‐kDa Fragment of Merozoite Surface Protein 1 in a Transmigrant Population Requires Multiple Infections

(2008) E. Elsa Herdiana Murhandarwati et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya

(2008) Wendy P O'Meara et al.   LANCET

Evaluation of immunoglobulin purification methods and their impact on quality and yield of antigen-specific antibodies

(2008) Elke S Bergmann-Leitner et al.   MALARIA JOURNAL

Immunity to malaria: more questions than answers

(2008) Jean Langhorne et al.   NATURE IMMUNOLOGY

Efficacy of RTS,S/AS01E Vaccine against Malaria in Children 5 to 17 Months of Age

(2008) Philip Bejon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial

(2008) Fiona M. Thompson et al.   PLoS One

Acquisition of Growth-Inhibitory Antibodies against Blood-Stage Plasmodium falciparum

(2008) Fiona J. McCallum et al.   PLoS One

Antibody-Mediated Growth Inhibition of Plasmodium falciparum: Relationship to Age and Protection from Parasitemia in Kenyan Children and Adults

(2008) Arlene E. Dent et al.   PLoS One