Sterol Regulatory Element-Binding Protein-1c Regulates Inflammasome Activation in Gingival Fibroblasts Infected with High-Glucose-Treated Porphyromonas gingivalis

Hericium erinaceus mycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade

(2016) Hsing-Chun Kuo et al.   Journal of Translational Medicine

Moniliformediquinone as a potential therapeutic agent, inactivation of hepatic stellate cell and inhibition of liver fibrosis in vivo

(2016) Tsui-Hwa Tseng et al.   Journal of Translational Medicine

Inhibitory effect of Erinacines A on the growth of DLD-1 colorectal cancer cells is induced by generation of reactive oxygen species and activation of p70S6K and p21

(2016) Chien-Chang Lu et al.   Journal of Functional Foods

The Association of CXC Receptor 4 Mediated Signaling Pathway with Oxaliplatin-Resistant Human Colorectal Cancer Cells

(2016) Wen-Shih Huang et al.   PLoS One

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

SREBP-1c overactivates ROS-mediated hepatic NF-κB inflammatory pathway in dairy cows with fatty liver

(2015) Xinwei Li et al.   CELLULAR SIGNALLING

Transcriptional regulation of hepatic lipogenesis

(2015) Yuhui Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation

(2015) Annette Ives et al.   Nature Communications

Chronic inflammation aggravates metabolic disorders of hepatic fatty acids in high-fat diet-induced obese mice

(2015) Lei Zhao et al.   Scientific Reports

Activation of the NLRP3 inflammasome in Porphyromonas gingivalis-accelerated atherosclerosis

(2015) Yohei Yamaguchi et al.   Pathogens and Disease

TNF-α induces cytosolic phospholipase A2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells

(2014) Chuen-Mao Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mechanisms and Functions of Inflammasomes

(2014) Mohamed Lamkanfi et al.   CELL

Endothelial dysfunction

(2014) Zhen Chen et al.   CURRENT OPINION IN LIPIDOLOGY

Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

(2014) Un Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bacterial invasion and persistence: critical events in the pathogenesis of periodontitis?

(2014) S. Ji et al.   JOURNAL OF PERIODONTAL RESEARCH

Identification of a Role for the PI3K/AKT/mTOR Signaling Pathway in Innate Immune Cells

(2014) Songbo Xie et al.   PLoS One

Differential Regulation of Human Aortic Smooth Muscle Cell Proliferation by Monocyte-Derived Macrophages from Diabetic Patients

(2014) Te-Chuan Chen et al.   PLoS One

Porphyromonas gingivalis: Major Periodontopathic Pathogen Overview

(2014) Jaroslav Mysak et al.   Journal of Immunology Research

Integrin α5β1-fimbriae binding and actin rearrangement are essential for Porphyromonas gingivalis invasion of osteoblasts and subsequent activation of the JNK pathway

(2013) Wenjian Zhang et al.   BMC MICROBIOLOGY

Regulation of ICAM-1 expression in gingival fibroblasts infected with high-glucose-treatedP. gingivalis

(2013) Li-Ching Chang et al.   CELLULAR MICROBIOLOGY

Activation of NLRP3 and AIM2 Inflammasomes by Porphyromonas gingivalis Infection

(2013) Eunjoo Park et al.   INFECTION AND IMMUNITY

Activation of Sterol Regulatory Element Binding Protein and NLRP3 Inflammasome in Atherosclerotic Lesion Development in Diabetic Pigs

(2013) Yu Li et al.   PLoS One

Nlrp3 Inflammasome Activation in Type 2 Diabetes: Is It Clinically Relevant?

(2012) Vishwa Deep Dixit   DIABETES

Upregulated NLRP3 Inflammasome Activation in Patients With Type 2 Diabetes

(2012) Hye-Mi Lee et al.   DIABETES

Hepatitis C virus core protein stimulates fibrogenesis in hepatic stellate cells involving the obese receptor

(2012) Ching-Fen Wu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Complement Protein C1q Directs Macrophage Polarization and Limits Inflammasome Activity during the Uptake of Apoptotic Cells

(2012) M. E. Benoit et al.   JOURNAL OF IMMUNOLOGY

Regulation of cyclooxygenase-2 expression in human bladder epithelial cells infected with type I fimbriated uropathogenic E. coli

(2011) Te-Chuan Chen et al.   CELLULAR MICROBIOLOGY

Non-surgical periodontal therapy with and without subgingival minocycline administration in patients with poorly controlled type II diabetes: a randomized controlled clinical trial

(2011) Shih-Jung Lin et al.   Clinical Oral Investigations

High Glucose-treated Macrophages Augment E-Selectin Expression in Endothelial Cells

(2011) Te-Chuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TLR4 Signaling via MyD88 and TRIF Differentially Shape the CD4+ T Cell Response to Porphyromonas gingivalis Hemagglutinin B

(2011) D. E. Gaddis et al.   JOURNAL OF IMMUNOLOGY

Periodontal treatment with topical antibiotics improves glycemic control in association with elevated serum adiponectin in patients with type 2 diabetes mellitus

(2011) Pariksha Bharti et al.   Obesity Research & Clinical Practice

Periodontitis: a polymicrobial disruption of host homeostasis

(2010) Richard P. Darveau   NATURE REVIEWS MICROBIOLOGY

mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis: Fig. 1.

(2010) Mathieu Laplante et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and regulation of the NALP3 inflammasome complex in periodontal diseases

(2009) N. Bostanci et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to Porphyromonas gingivalis Fimbriae

(2009) G. Hajishengallis et al.   JOURNAL OF IMMUNOLOGY

Surface components ofPorphyromonas gingivalis

(2008) F. Yoshimura et al.   JOURNAL OF PERIODONTAL RESEARCH