Identification of a Role for the PI3K/AKT/mTOR Signaling Pathway in Innate Immune Cells

Identification of a cytoplasmic linker protein as a potential target for neovascularization

(2014) Songbo Xie et al.   ATHEROSCLEROSIS

Deregulation of PI3K/Akt/mTOR Signaling Pathways by Isoflavones and its Implication in Cancer Treatment

(2013) Aamir Ahmad et al.   Anti-Cancer Agents in Medicinal Chemistry

Angiogenic capacity of M1- and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9

(2013) E. Zajac et al.   BLOOD

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Pivotal Roles of Monocytes/Macrophages in Stroke

(2013) Tsuyoshi Chiba et al.   MEDIATORS OF INFLAMMATION

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Cep70 contributes to angiogenesis by modulating microtubule rearrangement and stimulating cell polarization and migration

(2012) Xingjuan Shi et al.   CELL CYCLE

Innate immunosenescence: Effect of aging on cells and receptors of the innate immune system in humans

(2012) Rafael Solana et al.   SEMINARS IN IMMUNOLOGY

Characterization of polarized THP-1 macrophages and polarizing ability of LPS and food compounds

(2012) Wasaporn Chanput et al.   Food & Function

Gr1+ Macrophages and Dendritic Cells Dominate the Inflammatory Infiltrate 12 h After Experimental Intracerebral Hemorrhage

(2012) Matthew D. Hammond et al.   Translational Stroke Research

Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls

(2011) Marcella Reale et al.   BMC NEUROSCIENCE

PI3K Functions in Cancer Progression, Anticancer Immunity and Immune Evasion by Tumors

(2011) Francesco Dituri et al.   Clinical & Developmental Immunology

Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)-1 and an emerging role for cytokines beyond IL-1

(2011) R. Goldbach-Mansky   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet-Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

(2011) F. C. McGillicuddy et al.   DIABETES

A class IA PI3K controls inflammatory cytokine production in human neutrophils

(2011) Carl F. Fortin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model

(2011) Sebastian Jimenez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity, insulin resistance and free fatty acids

(2011) Guenther Boden   Current Opinion in Endocrinology Diabetes and Obesity

Microtubule-associated deacetylase HDAC6 promotes angiogenesis by regulating cell migration in an EB1-dependent manner

(2011) Dengwen Li et al.   Protein & Cell

PI3K p110  regulates T-cell cytokine production during primary and secondary immune responses in mice and humans

(2010) D. R. Soond et al.   BLOOD

M2 Macrophages Phagocytose Rituximab-Opsonized Leukemic Targets More Efficiently than M1 Cells In Vitro

(2009) M. Leidi et al.   JOURNAL OF IMMUNOLOGY

PI3K p110  Positively Regulates Lipopolysaccharide-Induced IL-12 Production in Human Macrophages and Dendritic Cells and JNK1 Plays a Novel Role

(2009) M. Utsugi et al.   JOURNAL OF IMMUNOLOGY

The PTEN/PI3K/AKT Signalling Pathway in Cancer, Therapeutic Implications

(2008) Amancio Carnero et al.   CURRENT CANCER DRUG TARGETS