Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation
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Title
Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation
Authors
Keywords
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Journal
eLife
Volume 5, Issue -, Pages -
Publisher
eLife Sciences Organisation, Ltd.
Online
2016-03-11
DOI
10.7554/elife.10860
References
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Related references
Note: Only part of the references are listed.- IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
- (2014) A. Kernytsky et al. BLOOD
- D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice
- (2014) E. A. Akbay et al. GENES & DEVELOPMENT
- An open investigation of the reproducibility of cancer biology research
- (2014) Timothy M Errington et al. eLife
- IDH mutations in tumorigenesis and their potential role as novel therapeutic targets
- (2013) Daniel Krell et al. Future Oncology
- Isocitrate dehydrogenase mutations in leukemia
- (2013) Anna Sophia McKenney et al. JOURNAL OF CLINICAL INVESTIGATION
- Histone 3 Lysine 9 Trimethylation Is Differentially Associated With Isocitrate Dehydrogenase Mutations in Oligodendrogliomas and High-Grade Astrocytomas
- (2013) Sriram Venneti et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation Patterns during Adipocyte Differentiation
- (2013) T. Londono Gentile et al. MOLECULAR AND CELLULAR BIOLOGY
- IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma
- (2013) Chunzhi Zhang et al. NEURO-ONCOLOGY
- A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation
- (2012) C. G. Duncan et al. GENOME RESEARCH
- The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-Hydroxyglutarate Depends on Allele Specificity and Subcellular Compartmentalization
- (2012) Patrick S. Ward et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
- (2012) Sevin Turcan et al. NATURE
- IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
- (2012) Masato Sasaki et al. NATURE
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
- (2010) Patrick S. Ward et al. CANCER CELL
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
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