Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation
出版年份 2016 全文链接
标题
Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation
作者
关键词
-
出版物
eLife
Volume 5, Issue -, Pages -
出版商
eLife Sciences Organisation, Ltd.
发表日期
2016-03-11
DOI
10.7554/elife.10860
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
- (2014) A. Kernytsky et al. BLOOD
- D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice
- (2014) E. A. Akbay et al. GENES & DEVELOPMENT
- An open investigation of the reproducibility of cancer biology research
- (2014) Timothy M Errington et al. eLife
- IDH mutations in tumorigenesis and their potential role as novel therapeutic targets
- (2013) Daniel Krell et al. Future Oncology
- Isocitrate dehydrogenase mutations in leukemia
- (2013) Anna Sophia McKenney et al. JOURNAL OF CLINICAL INVESTIGATION
- Histone 3 Lysine 9 Trimethylation Is Differentially Associated With Isocitrate Dehydrogenase Mutations in Oligodendrogliomas and High-Grade Astrocytomas
- (2013) Sriram Venneti et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- DNMT1 Is Regulated by ATP-Citrate Lyase and Maintains Methylation Patterns during Adipocyte Differentiation
- (2013) T. Londono Gentile et al. MOLECULAR AND CELLULAR BIOLOGY
- IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma
- (2013) Chunzhi Zhang et al. NEURO-ONCOLOGY
- A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation
- (2012) C. G. Duncan et al. GENOME RESEARCH
- The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-Hydroxyglutarate Depends on Allele Specificity and Subcellular Compartmentalization
- (2012) Patrick S. Ward et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
- (2012) Sevin Turcan et al. NATURE
- IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
- (2012) Masato Sasaki et al. NATURE
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
- (2010) Patrick S. Ward et al. CANCER CELL
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started