Using zebrafish in systems toxicology for developmental toxicity testing

Zebrafish as a systems toxicology model for developmental neurotoxicity testing

(2015) Yuhei Nishimura et al.   CONGENITAL ANOMALIES

From cutting edge to guideline: A first step in harmonization of the zebrafish embryotoxicity test (ZET) by describing the most optimal test conditions and morphology scoring system

(2015) Manon Beekhuijzen et al.   REPRODUCTIVE TOXICOLOGY

Evaluation of an alternative in vitro test battery for detecting reproductive toxicants in a grouping context

(2015) E. Dinant Kroese et al.   REPRODUCTIVE TOXICOLOGY

Optimization and Performance Assessment of the Chorion-Off [Dechorinated] Zebrafish Developmental Toxicity Assay

(2015) Julieta M. Panzica-Kelly et al.   TOXICOLOGICAL SCIENCES

Zebrafish as a systems toxicology model for developmental neurotoxicity testing

(2015) Yuhei Nishimura et al.   CONGENITAL ANOMALIES

Phenotype Classification of Zebrafish Embryos by Supervised Learning

(2015) Nathalie Jeanray et al.   PLoS One

Systems Toxicology: From Basic Research to Risk Assessment

(2014) Shana J. Sturla et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Historical control data on developmental toxicity studies in rodents

(2014) Makoto Ema et al.   CONGENITAL ANOMALIES

A critical appraisal of the process of regulatory implementation of novelin vivoandin vitromethods for chemical hazard and risk assessment

(2014) Aldert H. Piersma et al.   CRITICAL REVIEWS IN TOXICOLOGY

Middle and inner ear malformations in two siblings exposed to valproic acid during pregnancy: A case report

(2014) Evelyne Van Houtte et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Developmental toxicity assay using high content screening of zebrafish embryos

(2014) Susan Lantz-McPeak et al.   JOURNAL OF APPLIED TOXICOLOGY

Improvement of the evaluation method for teratogenicity using zebrafish embryos

(2014) Akihito Yamashita et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Molecular and morphological changes in zebrafish following transient ethanol exposure during defined developmental stages

(2014) Chengjin Zhang et al.   NEUROTOXICOLOGY AND TERATOLOGY

The Transcriptional Response to Oxidative Stress during Vertebrate Development: Effects of tert-Butylhydroquinone and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

(2014) Mark E. Hahn et al.   PLoS One

Zebrafish embryotoxicity test for developmental (neuro)toxicity: Demo case of an integrated screening approach system using anti-epileptic drugs

(2014) Anna Beker van Woudenberg et al.   REPRODUCTIVE TOXICOLOGY

Fishing for Teratogens: A Consortium Effort for a Harmonized Zebrafish Developmental Toxicology Assay

(2014) Jonathan S. Ball et al.   TOXICOLOGICAL SCIENCES

An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods

(2014) Miguel A. Sogorb et al.   TOXICOLOGY LETTERS

Developmental Toxicity of Diclofenac and Elucidation of Gene Regulation in zebrafish (Danio rerio)

(2014) Jia-Bin Chen et al.   Scientific Reports

Human alcohol-related neuropathology

(2013) Suzanne M. de la Monte et al.   ACTA NEUROPATHOLOGICA

DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-Implications for the fish embryo test (FET)

(2013) B. Kais et al.   AQUATIC TOXICOLOGY

FishFace: interactive atlas of zebrafish craniofacial development at cellular resolution

(2013) B Eames et al.   BMC DEVELOPMENTAL BIOLOGY

The behavioral effects of acute Δ9-tetrahydrocannabinol and heroin (diacetylmorphine) exposure in adult zebrafish

(2013) Adam Michael Stewart et al.   BRAIN RESEARCH

Zebrafish: A model vertebrate suitable for the analysis of human genetic disorders

(2013) Satoshi Ota et al.   CONGENITAL ANOMALIES

Zebrafish as a model system to study toxicology

(2013) Yu-Jie Dai et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Fundamental Approaches to the Study of Zebrafi sh Nutrition

(2013) S. A. Watts et al.   ILAR JOURNAL

Zebrafish Housing Systems: A Review of Basic Operating Principles and Considerations for Design and Functionality

(2013) C. Lawrence et al.   ILAR JOURNAL

Aspects of Larval Rearing

(2013) C. Wilson   ILAR JOURNAL

Zebrafish Breeding in the Laboratory Environment

(2013) A. Nasiadka et al.   ILAR JOURNAL

Calcium influx through L-type CaV1.2 Ca2+ channels regulates mandibular development

(2013) Kapil V. Ramachandran et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct Functional and Temporal Requirements for Zebrafish Hdac1 during Neural Crest-Derived Craniofacial and Peripheral Neuron Development

(2013) Myron S. Ignatius et al.   PLoS One

Effects of the benzimidazole anthelmintic drug flubendazole on rat embryos in vitro

(2013) Monica Longo et al.   REPRODUCTIVE TOXICOLOGY

Multidimensional In Vivo Hazard Assessment Using Zebrafish

(2013) Lisa Truong et al.   TOXICOLOGICAL SCIENCES

Transcriptomic analysis in the developing zebrafish embryo after compound exposure: Individual gene expression and pathway regulation

(2013) Sanne A.B. Hermsen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Automated Processing of Zebrafish Imaging Data: A Survey

(2013) Ralf Mikut et al.   Zebrafish

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

(2012) Anne K. Krug et al.   ARCHIVES OF TOXICOLOGY

Interference with xenobiotic metabolic activity by the commonly used vehicle solvents dimethylsulfoxide and methanol in zebrafish (Danio rerio) larvae but not Daphnia magna

(2012) Rhiannon M. David et al.   CHEMOSPHERE

Historical control data on prenatal developmental toxicity studies in rabbits

(2012) Makoto Ema et al.   CONGENITAL ANOMALIES

Drug-Likeness and Increased Hydrophobicity of Commercially Available Compound Libraries for Drug Screening

(2012) Johannes Zuegg et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Antiepileptic drugs (AEDs) during pregnancy and risk of congenital jaw and oral malformation

(2012) J Koo et al.   ORAL DISEASES

Evaluation of 14 Organic Solvents and Carriers for Screening Applications in Zebrafish Embryos and Larvae

(2012) Jan Maes et al.   PLoS One

Testing strategies for embryo-fetal toxicity of human pharmaceuticals. Animal models vs. in vitro approaches

(2012) Jan Willem van der Laan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Consistency of morphological endpoints used to assess developmental timing in zebrafish (Danio rerio) across a temperature gradient

(2012) Amy Beasley et al.   REPRODUCTIVE TOXICOLOGY

Albendazole causes stage-dependent developmental toxicity and is deactivated by a mammalian metabolization system in a modified zebrafish embryotoxicity test

(2012) Anna Mattsson et al.   REPRODUCTIVE TOXICOLOGY

A panel of biological tests reveals developmental effects of pharmaceutical pollutants on late stage zebrafish embryos

(2012) Benoist Pruvot et al.   REPRODUCTIVE TOXICOLOGY

Paraoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicity

(2012) Lucio G. Costa et al.   TOXICOLOGY

Assessment of developmental delay in the zebrafish embryo teratogenicity assay

(2012) E. Teixidó et al.   TOXICOLOGY IN VITRO

Developmental exposures to ethanol or dimethylsulfoxide at low concentrations alter locomotor activity in larval zebrafish: Implications for behavioral toxicity bioassays

(2011) Te-Hao Chen et al.   AQUATIC TOXICOLOGY

Zebrafish-As an integrative model for twenty-first century toxicity testing

(2011) Nisha S. Sipes et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Gastrulation in rabbit blastocysts depends on insulin and insulin-like-growth-factor 1

(2011) René Thieme et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Large-Scale Assessment of the Zebrafish Embryo as a Possible Predictive Model in Toxicity Testing

(2011) Shaukat Ali et al.   PLoS One

Chemical class-specific gene expression changes in the zebrafish embryo after exposure to glycol ether alkoxy acids and 1,2,4-triazole antifungals

(2011) Sanne A.B. Hermsen et al.   REPRODUCTIVE TOXICOLOGY

Zebrafish developmental toxicity assay: A fishy solution to reproductive toxicity screening, or just a red herring?

(2011) Kathleen Van den Bulck et al.   REPRODUCTIVE TOXICOLOGY

Feasibility study of the zebrafish assay as an alternative method to screen for developmental toxicity and embryotoxicity using a training set of 27 compounds

(2011) Ingrid W.T. Selderslaghs et al.   REPRODUCTIVE TOXICOLOGY

Inter-laboratory assessment of a harmonized zebrafish developmental toxicology assay – Progress report on phase I

(2011) A.-L. Gustafson et al.   REPRODUCTIVE TOXICOLOGY

Zebrafish developmental screening of the ToxCast™ Phase I chemical library

(2011) S. Padilla et al.   REPRODUCTIVE TOXICOLOGY

Homoplasy: From Detecting Pattern to Determining Process and Mechanism of Evolution

(2011) D. B. Wake et al.   SCIENCE

Adverse Outcome Pathways during Early Fish Development: A Conceptual Framework for Identification of Chemical Screening and Prioritization Strategies

(2011) David C. Volz et al.   TOXICOLOGICAL SCIENCES

Zebrafish (Danio rerio) embryos as a model for testing proteratogens

(2011) Stefan Weigt et al.   TOXICOLOGY

Comparison of the mouse Embryonic Stem cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles

(2011) Esther de Jong et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Morphological score assignment guidelines for the dechorionated zebrafish teratogenicity assay

(2010) Julieta M. Panzica-Kelly et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Development of a zebrafish embryo teratogenicity assay and quantitative prediction model

(2010) Kimberly C. Brannen et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Oxygen requirements of zebrafish (Danio rerio) embryos in embryo toxicity tests with environmental samples

(2010) Ruben Strecker et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Cell-based and cytokine-directed chemical screen to identify potential anti-multiple myeloma agents

(2010) Rentian Feng et al.   LEUKEMIA RESEARCH

Zebrafish embryos exposed to alcohol undergo abnormal development of motor neurons and muscle fibers

(2010) Nicole J. Sylvain et al.   NEUROTOXICOLOGY AND TERATOLOGY

Potency ranking of valproic acid analogues as to inhibition of cardiac differentiation of embryonic stem cells in comparison to their in vivo embryotoxicity

(2010) E. de Jong et al.   REPRODUCTIVE TOXICOLOGY

Inbreeding Depression and Outbreeding Depression Are Evident in Wild-Type Zebrafish Lines

(2010) Christopher A. Monson et al.   Zebrafish

Deciphering the role of Shh signaling in axial defects produced by ethanol exposure

(2009) Evyn J. Loucks et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

A novel in vitro system for the determination of bioconcentration factors and the internal dose in zebrafish (Danio rerio) eggs

(2009) René Schreiber et al.   CHEMOSPHERE

Long and winding roads: Testis differentiation in zebrafish

(2009) Laszlo Orban et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Deep homology and the origins of evolutionary novelty

(2009) Neil Shubin et al.   NATURE

Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio)

(2009) E. Lammer et al.   TOXICOLOGY IN VITRO

The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing

(2008) Stefan Scholz et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH