Evolution of the Cytolytic Pore-Forming Proteins (Actinoporins) in Sea Anemones

Tissue-Specific Venom Composition and Differential Gene Expression in Sea Anemones

(2016) Jason Macrander et al.   Genome Biology and Evolution

Intragenome Diversity of Gene Families Encoding Toxin-like Proteins in Venomous Animals

(2016) Ricardo C. Rodríguez de la Vega et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Differences in activity of actinoporins are related with the hydrophobicity of their N-terminus

(2015) Uris Ros et al.   BIOCHIMIE

Characterization of the Lipid-Binding Site of Equinatoxin II by NMR and Molecular Dynamics Simulation

(2015) Daniel K. Weber et al.   BIOPHYSICAL JOURNAL

Gene duplications are extensive and contribute significantly to the toxic proteome of nematocysts isolated from Acropora digitifera (Cnidaria: Anthozoa: Scleractinia)

(2015) Ranko Gacesa et al.   BMC GENOMICS

A RNA-seq approach to identify putative toxins from acrorhagi in aggressive and non-aggressive Anthopleura elegantissima polyps

(2015) Jason Macrander et al.   BMC GENOMICS

Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin fromActinia fragacea

(2015) Koldo Morante et al.   FEBS LETTERS

Evolution of an Ancient Venom: Recognition of a Novel Family of Cnidarian Toxins and the Common Evolutionary Origin of Sodium and Potassium Neurotoxins in Sea Anemone

(2015) Mahdokht Jouiaei et al.   MOLECULAR BIOLOGY AND EVOLUTION

The genome ofAiptasia, a sea anemone model for coral symbiosis

(2015) Sebastian Baumgarten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-copy venom genes hidden in de novo transcriptome assemblies, a cautionary tale with the snakelocks sea anemone Anemonia sulcata (Pennant, 1977)

(2015) Jason Macrander et al.   TOXICON

The multigene families of actinoporins (part I): Isoforms and genetic structure

(2015) A. Valle et al.   TOXICON

Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

(2015) Koji Tanaka et al.   Nature Communications

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Production of a reference transcriptome and transcriptomic database (EdwardsiellaBase) for the lined sea anemone, Edwardsiella lineata, a parasitic cnidarian

(2014) Derek J Stefanik et al.   BMC GENOMICS

The sea anemone actinoporin (Arg-Gly-Asp) conserved motif is involved in maintaining the competent oligomerization state of these pore-forming toxins

(2014) Sara García-Linares et al.   FEBS Journal

The Dynamically Evolving Nematocyst Content of an Anthozoan, a Scyphozoan, and a Hydrozoan

(2014) Tamar Rachamim et al.   MOLECULAR BIOLOGY AND EVOLUTION

Comprehensive variation discovery in single human genomes

(2014) Neil I Weisenfeld et al.   NATURE GENETICS

Hidden among Sea Anemones: The First Comprehensive Phylogenetic Reconstruction of the Order Actiniaria (Cnidaria, Anthozoa, Hexacorallia) Reveals a Novel Group of Hexacorals

(2014) Estefanía Rodríguez et al.   PLoS One

Hydra actinoporin-like toxin-1, an unusual hemolysin from the nematocyst venom of Hydra magnipapillata which belongs to an extended gene family

(2014) Eliezra Glasser et al.   TOXICON

Three-dimensional structure of the actinoporin sticholysin I. Influence of long-distance effects on protein function

(2013) Sara García-Linares et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

2NH and 3OH are crucial structural requirements in sphingomyelin for sticholysin II binding and pore formation in bilayer membranes

(2013) Terhi Maula et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

(2012) M. Kearse et al.   BIOINFORMATICS

The Nematocyst: a molecular map of the Cnidarian stinging organelle

(2012) Anna Beckmann et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Analysis of Soluble Protein Contents from the Nematocysts of a Model Sea Anemone Sheds Light on Venom Evolution

(2012) Yehu Moran et al.   MARINE BIOTECHNOLOGY

Sea Anemone (Cnidaria, Anthozoa, Actiniaria) Toxins: An Overview

(2012) Bárbara Frazão et al.   Marine Drugs

Intrinsic local disorder and a network of charge-charge interactions are key to actinoporin membrane disruption and cytotoxicity

(2011) Miguel A. Pardo-Cea et al.   FEBS Journal

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Neurotoxin localization to ectodermal gland cells uncovers an alternative mechanism of venom delivery in sea anemones

(2011) Y. Moran et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structural Insights into the Oligomerization and Architecture of Eukaryotic Membrane Pore-Forming Toxins

(2011) Ariel E. Mechaly et al.   STRUCTURE

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

Actinoporins from the sea anemones, tropical Radianthus macrodactylus and northern Oulactis orientalis: Comparative analysis of structure–function relationships

(2010) Margarita Monastyrnaya et al.   TOXICON

Molecular characterization on the genome structure of hemolysin toxin isoforms isolated from sea anemone Actineria villosa and Phyllodiscus semoni

(2010) Gen-ichiro Uechi et al.   TOXICON

An actinoporin plays a key role in water stress in the mossPhyscomitrella patens

(2009) Quoc Truong Hoang et al.   NEW PHYTOLOGIST

In vivo effects of cnidarian toxins and venoms

(2009) Dušan Šuput   TOXICON

Sea anemone cytolysins as toxic components of immunotoxins

(2009) Mayra Tejuca et al.   TOXICON

Molecular mechanism of pore formation by actinoporins

(2009) Katarina Črnigoj Kristan et al.   TOXICON

Sticholysins, two pore-forming toxins produced by the Caribbean Sea anemone Stichodactyla helianthus: Their interaction with membranes

(2009) Carlos Álvarez et al.   TOXICON

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS

Molecular Determinants of Sphingomyelin Specificity of a Eukaryotic Pore-forming Toxin

(2008) Biserka Bakrač et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A multigene family of Heteractis magnificalysins (HMgs)

(2008) Yawen Wang et al.   TOXICON