Evolution of an Ancient Venom: Recognition of a Novel Family of Cnidarian Toxins and the Common Evolutionary Origin of Sodium and Potassium Neurotoxins in Sea Anemone

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders

(2014) Sandy S Pineda et al.   BMC GENOMICS

Production of a reference transcriptome and transcriptomic database (EdwardsiellaBase) for the lined sea anemone, Edwardsiella lineata, a parasitic cnidarian

(2014) Derek J Stefanik et al.   BMC GENOMICS

Chironex fleckeri(Box Jellyfish) Venom Proteins

(2014) Diane L. Brinkman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores

(2014) Jonas E. Jensen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): Biodiscovery, clinical and evolutionary implications

(2014) Kartik Sunagar et al.   Journal of Proteomics

Hidden among Sea Anemones: The First Comprehensive Phylogenetic Reconstruction of the Order Actiniaria (Cnidaria, Anthozoa, Hexacorallia) Reveals a Novel Group of Hexacorals

(2014) Estefanía Rodríguez et al.   PLoS One

Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails

(2014) Sébastien Dutertre et al.   Nature Communications

Characterization of differential transcript abundance through time during Nematostella vectensis development

(2013) Rebecca Helm et al.   BMC GENOMICS

BcsTx3 is a founder of a novel sea anemone toxin family of potassium channel blocker

(2013) Diego J. B. Orts et al.   FEBS Journal

Evidence for Cnidaria-like behavior in ca. 560 Ma Ediacaran Aspidella

(2013) Latha R. Menon et al.   GEOLOGY

Molecular Phylogeny and Evolution of the Proteins Encoded by Coleoid (Cuttlefish, Octopus, and Squid) Posterior Venom Glands

(2013) Tim Ruder et al.   JOURNAL OF MOLECULAR EVOLUTION

Dracula's children: Molecular evolution of vampire bat venom

(2013) Dolyce H.W. Low et al.   Journal of Proteomics

FUBAR: A Fast, Unconstrained Bayesian AppRoximation for Inferring Selection

(2013) B. Murrell et al.   MOLECULAR BIOLOGY AND EVOLUTION

Molecular Evolution of Vertebrate Neurotrophins: Co-Option of the Highly Conserved Nerve Growth Factor Gene into the Advanced Snake Venom Arsenalf

(2013) Kartik Sunagar et al.   PLoS One

Three-Fingered RAVERs: Rapid Accumulation of Variations in Exposed Residues of Snake Venom Toxins

(2013) Kartik Sunagar et al.   Toxins

Evolution Stings: The Origin and Diversification of Scorpion Toxin Peptide Scaffolds

(2013) Kartik Sunagar et al.   Toxins

Developing the anemone Aiptasia as a tractable model for cnidarian-dinoflagellate symbiosis: the transcriptome of aposymbiotic A. pallida

(2012) Erik M Lehnert et al.   BMC GENOMICS

A natural point mutation changes both target selectivity and mechanism of action of sea anemone toxins

(2012) Steve Peigneur et al.   FASEB JOURNAL

Differential Evolution and Neofunctionalization of Snake Venom Metalloprotease Domains

(2012) Andreas Brust et al.   MOLECULAR & CELLULAR PROTEOMICS

Evolution of CRISPs Associated with Toxicoferan-Reptilian Venom and Mammalian Reproduction

(2012) K. Sunagar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Recurrent Horizontal Transfer of Bacterial Toxin Genes to Eukaryotes

(2012) Y. Moran et al.   MOLECULAR BIOLOGY AND EVOLUTION

Extensive and Continuous Duplication Facilitates Rapid Evolution and Diversification of Gene Families

(2012) Dan Chang et al.   MOLECULAR BIOLOGY AND EVOLUTION

jModelTest 2: more models, new heuristics and parallel computing

(2012) Diego Darriba et al.   NATURE METHODS

MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space

(2012) Fredrik Ronquist et al.   SYSTEMATIC BIOLOGY

Complex cocktails: the evolutionary novelty of venoms

(2012) Nicholas R. Casewell et al.   TRENDS IN ECOLOGY & EVOLUTION

Dynamic evolution of venom proteins in squamate reptiles

(2012) Nicholas R. Casewell et al.   Nature Communications

Detecting Individual Sites Subject to Episodic Diversifying Selection

(2012) Ben Murrell et al.   PLoS Genetics

The behavior of sea anemone actinoporins at the water–membrane interface

(2011) Lucía García-Ortega et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

ProtTest 3: fast selection of best-fit models of protein evolution

(2011) Diego Darriba et al.   BIOINFORMATICS

Evolutionary crossroads in developmental biology: Cnidaria

(2011) U. Technau et al.   DEVELOPMENT

The biology of coral metamorphosis: Molecular responses of larvae to inducers of settlement and metamorphosis

(2011) L.C. Grasso et al.   DEVELOPMENTAL BIOLOGY

Domain Loss Facilitates Accelerated Evolution and Neofunctionalization of Duplicate Snake Venom Metalloproteinase Toxin Genes

(2011) N. R. Casewell et al.   MOLECULAR BIOLOGY AND EVOLUTION

Estimation of divergence times in cnidarian evolution based on mitochondrial protein-coding genes and the fossil record

(2011) Eunji Park et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Using the Acropora digitifera genome to understand coral responses to environmental change

(2011) Chuya Shinzato et al.   NATURE

InterPro in 2011: new developments in the family and domain prediction database

(2011) S. Hunter et al.   NUCLEIC ACIDS RESEARCH

Neurotoxin localization to ectodermal gland cells uncovers an alternative mechanism of venom delivery in sea anemones

(2011) Y. Moran et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Cambrian Conundrum: Early Divergence and Later Ecological Success in the Early History of Animals

(2011) D. H. Erwin et al.   SCIENCE

The dynamic genome of Hydra

(2010) Jarrod A. Chapman et al.   NATURE

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

A genomic view of 500 million years of cnidarian evolution

(2010) Robert E. Steele et al.   TRENDS IN GENETICS

Calibrating the chelicerate clock: a paleontological reply to Jeyaprakash and Hoy

(2009) Jason A. Dunlop et al.   EXPERIMENTAL AND APPLIED ACAROLOGY

Positions under Positive Selection--Key for Selectivity and Potency of Scorpion  -Toxins

(2009) H. Weinberger et al.   MOLECULAR BIOLOGY AND EVOLUTION

Identification and Gene Expression Analysis of a Taxonomically Restricted Cysteine-Rich Protein Family in Reef-Building Corals

(2009) Shinichi Sunagawa et al.   PLoS One

Actions of sea anemone type 1 neurotoxins on voltage-gated sodium channel isoforms

(2009) Enzo Wanke et al.   TOXICON

Sea anemone toxins affecting voltage-gated sodium channels – molecular and evolutionary features

(2009) Yehu Moran et al.   TOXICON

Discovery and characterization of cnidarian peptide toxins that affect neuronal potassium ion channels

(2009) Olga Castañeda et al.   TOXICON

The phylum Cnidaria and investigations of its toxins and venoms until 1990

(2009) Tom Turk et al.   TOXICON

Molecular mechanism of pore formation by actinoporins

(2009) Katarina Črnigoj Kristan et al.   TOXICON

Kunitz-type protease inhibitors from acrorhagi of three species of sea anemones

(2008) Sonomi Minagawa et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Response of the symbiotic cnidarian Anthopleura elegantissima transcriptome to temperature and UV increase

(2008) Sophie Richier et al.   Comparative Biochemistry and Physiology D-Genomics & Proteomics

Proteomics of the neurotoxic fraction from the sea anemone Bunodosoma cangicum venom: Novel peptides belonging to new classes of toxins

(2008) André Junqueira Zaharenko et al.   Comparative Biochemistry and Physiology D-Genomics & Proteomics

Novel peptide toxins from the sea anemone Stichodactyla haddoni

(2008) Tomohiro Honma et al.   PEPTIDES

Evolution of complex structures: minicollagens shape the cnidarian nematocyst

(2008) Charles N. David et al.   TRENDS IN GENETICS

Osmotically driven prey disintegration in the gastrovascular cavity of the green hydra by a pore-forming protein

(2007) Daniel Sher et al.   FASEB JOURNAL