Structural basis for self-assembly of a cytolytic pore lined by protein and lipid

2NH and 3OH are crucial structural requirements in sphingomyelin for sticholysin II binding and pore formation in bilayer membranes

(2013) Terhi Maula et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Disulfide-bond scanning reveals assembly state and β-strand tilt angle of the PFO β-barrel

(2013) Takehiro K Sato et al.   Nature Chemical Biology

Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism

(2013) Matteo T Degiacomi et al.   Nature Chemical Biology

Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins

(2012) Michelle A Dunstone et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Pores of the toxin FraC assemble into 2D hexagonal clusters in both crystal structures and model membranes

(2012) Ariel E. Mechaly et al.   JOURNAL OF STRUCTURAL BIOLOGY

Sea Anemone (Cnidaria, Anthozoa, Actiniaria) Toxins: An Overview

(2012) Bárbara Frazão et al.   Marine Drugs

Viroporins: structure and biological functions

(2012) José Luis Nieva et al.   NATURE REVIEWS MICROBIOLOGY

The behavior of sea anemone actinoporins at the water–membrane interface

(2011) Lucía García-Ortega et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Rapid Assembly of a Multimeric Membrane Protein Pore

(2011) James R. Thompson et al.   BIOPHYSICAL JOURNAL

Random Microseeding: A Theoretical and Practical Exploration of Seed Stability and Seeding Techniques for Successful Protein Crystallization

(2011) Patrick D. Shaw Stewart et al.   CRYSTAL GROWTH & DESIGN

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Crystal structure of the Vibrio cholerae cytolysin heptamer reveals common features among disparate pore-forming toxins

(2011) S. De et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the octameric pore of staphylococcal  -hemolysin reveals the  -barrel pore formation mechanism by two components

(2011) K. Yamashita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Insights into the Oligomerization and Architecture of Eukaryotic Membrane Pore-Forming Toxins

(2011) Ariel E. Mechaly et al.   STRUCTURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure and assembly of pore-forming proteins

(2010) Ioan Iacovache et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Production and biophysical characterization of the CorA transporter from Methanosarcina mazei

(2009) David Veesler et al.   ANALYTICAL BIOCHEMISTRY

The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes

(2009) Alexander F. Kintzer et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

(2009) Toshimitsu Kawate et al.   NATURE

The structure of a cytolytic α-helical toxin pore reveals its assembly mechanism

(2009) Marcus Mueller et al.   NATURE

Purification, cloning and characterization of fragaceatoxin C, a novel actinoporin from the sea anemone Actinia fragacea

(2009) Augusto Bellomio et al.   TOXICON

Pore formation: An ancient yet complex form of attack

(2008) Ioan Iacovache et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Equinatoxin II Permeabilizing Activity Depends on the Presence of Sphingomyelin and Lipid Phase Coexistence

(2008) Peter Schön et al.   BIOPHYSICAL JOURNAL

Molecular Determinants of Sphingomyelin Specificity of a Eukaryotic Pore-forming Toxin

(2008) Biserka Bakrač et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calorimetric Scrutiny of Lipid Binding by Sticholysin II Toxin Mutants

(2008) Jorge Alegre-Cebollada et al.   JOURNAL OF MOLECULAR BIOLOGY

A Lipidic-Sponge Phase Screen for Membrane Protein Crystallization

(2008) Annemarie B. Wöhri et al.   STRUCTURE

Disparate proteins use similar architectures to damage membranes

(2008) Gregor Anderluh et al.   TRENDS IN BIOCHEMICAL SCIENCES