Setting the Stage for Notch: The Drosophila Su(H)-Hairless Repressor Complex

The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways

(2016) Tilman Borggrefe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes

(2016) Franz Oswald et al.   NUCLEIC ACIDS RESEARCH

Chromatin signatures at Notch-regulated enhancers reveal large-scale changes in H3K56ac upon activation

(2015) L. Skalska et al.   EMBO JOURNAL

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation

(2015) Maria-Giuseppina Procopio et al.   NATURE CELL BIOLOGY

Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response

(2015) K. Hein et al.   Science Signaling

Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response

(2015) K. Hein et al.   Science Signaling

Loss of the Notch effector RBPJ promotes tumorigenesis

(2014) Iva Kulic et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Tumor Suppressor Ikaros Shapes the Repertoire of Notch Target Genes in T Cells

(2014) A.-S. Geimer Le Lay et al.   Science Signaling

Dynamic binding of RBPJ is determined by Notch signaling status

(2013) D. Castel et al.   GENES & DEVELOPMENT

Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling

(2013) Kelly J. Collins et al.   STRUCTURE

Fine-tuning of the intracellular canonical Notch signaling pathway

(2012) Tilman Borggrefe et al.   CELL CYCLE

Conformational Locking upon Cooperative Assembly of Notch Transcription Complexes

(2012) Sung Hee Choi et al.   STRUCTURE

Functional antagonism between histone H3K4 demethylases in vivo

(2011) L. Di Stefano et al.   GENES & DEVELOPMENT

Transcriptional Repression in the Notch Pathway

(2011) Bradley D. VanderWielen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster

(2011) Dieter Maier et al.   MOLECULAR BIOLOGY OF THE CELL

A SIRT1-LSD1 Corepressor Complex Regulates Notch Target Gene Expression and Development

(2011) Peter Mulligan et al.   MOLECULAR CELL

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

(2011) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J

(2010) Stephan Armin Wacker et al.   EMBO JOURNAL

Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex

(2010) R. Liefke et al.   GENES & DEVELOPMENT

Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

(2010) Kelly L Arnett et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Notch signaling pathway: Transcriptional regulation at Notch target genes

(2009) T. Borggrefe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Histone Chaperones ASF1 and NAP1 Differentially Modulate Removal of Active Histone Marks by LID-RPD3 Complexes during NOTCH Silencing

(2009) Yuri M. Moshkin et al.   MOLECULAR CELL

RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex

(2008) David R. Friedmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY