The Tumor Suppressor Ikaros Shapes the Repertoire of Notch Target Genes in T Cells

Ikaros Regulates Notch Target Gene Expression in Developing Thymocytes

(2014) S. Chari et al.   JOURNAL OF IMMUNOLOGY

Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation

(2013) I. Ferreiros-Vidal et al.   BLOOD

Dynamic binding of RBPJ is determined by Notch signaling status

(2013) D. Castel et al.   GENES & DEVELOPMENT

Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals

(2013) Beate Heizmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros

(2013) Hilde Schjerven et al.   NATURE IMMUNOLOGY

NOTCH1 Nuclear Interactome Reveals Key Regulators of Its Transcriptional Activity and Oncogenic Function

(2012) Ahmad Yatim et al.   MOLECULAR CELL

Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis

(2011) Jiangwen Zhang et al.   NATURE IMMUNOLOGY

Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters

(2011) Frederic Koch et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

(2011) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

(2010) R. Jeannet et al.   BLOOD

The Notch/Hes1 Pathway Sustains NF-κB Activation through CYLD Repression in T Cell Leukemia

(2010) Lluis Espinosa et al.   CANCER CELL

Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex

(2010) R. Liefke et al.   GENES & DEVELOPMENT

Hes1 Is a Critical but Context-Dependent Mediator of Canonical Notch Signaling in Lymphocyte Development and Transformation

(2010) Agnieszka A. Wendorff et al.   IMMUNITY

Notch Target Gene Deregulation and Maintenance of the Leukemogenic Phenotype Do Not Require RBP-J  in Ikaros Null Mice

(2010) S. Chari et al.   JOURNAL OF IMMUNOLOGY

Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies

(2010) Jon C Aster et al.   JOURNAL OF PATHOLOGY

GPAT: Retrieval of genomic annotation from large genomic position datasets

(2009) Arnaud Krebs et al.   BMC BIOINFORMATICS

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

The Notch signaling pathway: Transcriptional regulation at Notch target genes

(2009) T. Borggrefe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ikaros Directly Represses the Notch Target GeneHes1in a Leukemia T Cell Line

(2008) Katie L. Kathrein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras–initiated leukemia

(2008) Mark Y. Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development

(2008) E. Kleinmann et al.   MOLECULAR AND CELLULAR BIOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY