Functional Sites Induce Long-Range Evolutionary Constraints in Enzymes

Title
Functional Sites Induce Long-Range Evolutionary Constraints in Enzymes
Authors
Keywords
Evolutionary rate, Enzyme structure, Enzymes, Protein structure, Molecular evolution, Protein structure prediction, Protein structure databases, Sequence alignment
Journal
PLOS BIOLOGY
Volume 14, Issue 5, Pages e1002452
Publisher
Public Library of Science (PLoS)
Online
2016-05-04
DOI
10.1371/journal.pbio.1002452

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