IL-35 and Autoimmunity: a Comprehensive Perspective

Human CD4+HLA-G+ regulatory T cells are potent suppressors of graft-versus-host disease in vivo

(2014) Susann Pankratz et al.   FASEB JOURNAL

Ongoing activation of autoantigen-specific B cells in primary biliary cirrhosis

(2014) Jun Zhang et al.   HEPATOLOGY

Shotgun proteomics: Identification of unique protein profiles of apoptotic bodies from biliary epithelial cells

(2014) Ana Lleo et al.   HEPATOLOGY

Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2Rα−/− mice

(2014) Yuan Yao et al.   JOURNAL OF AUTOIMMUNITY

Murine autoimmune cholangitis requires two hits: Cytotoxic KLRG1+ CD8 effector cells and defective T regulatory cells

(2014) Wenting Huang et al.   JOURNAL OF AUTOIMMUNITY

Higher Circulating Levels of Chemokine CCL20 in Patients with Multiple Sclerosis: Evaluation of the Influences of Chemokine Gene Polymorphism, Gender, Treatment and Disease Pattern

(2014) A. Jafarzadeh et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

Interleukin-35 induces regulatory B cells that suppress autoimmune disease

(2014) Ren-Xi Wang et al.   NATURE MEDICINE

Regulatory B cells—IL-35 and IL-21 regulate the regulators

(2014) Thomas F. Tedder et al.   Nature Reviews Rheumatology

Contribution of IL-12/IL-35 Common Subunit p35 to Maintaining the Testicular Immune Privilege

(2014) Hayato Terayama et al.   PLoS One

Mechanisms of tissue injury in autoimmune liver diseases

(2014) Evaggelia Liaskou et al.   Seminars in Immunopathology

Breach of Tolerance: Primary Biliary Cirrhosis

(2014) Lifeng Wang et al.   SEMINARS IN LIVER DISEASE

Clonality, activated antigen-specific CD8+T cells, and development of autoimmune cholangitis in dnTGFβRII mice

(2013) Kazuhito Kawata et al.   HEPATOLOGY

IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: Implications for therapy

(2013) Chen-Yen Yang et al.   HEPATOLOGY

The role of natural killer cells in autoimmune liver disease: A comprehensive review

(2013) Kelly Hudspeth et al.   JOURNAL OF AUTOIMMUNITY

Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse

(2013) Yugo Ando et al.   JOURNAL OF AUTOIMMUNITY

Prevention of Autoimmune Diabetes by Ectopic Pancreatic  -Cell Expression of Interleukin-35

(2012) M. Bettini et al.   DIABETES

Antimitochondrial antibody heterogeneity and the xenobiotic etiology of primary biliary cirrhosis

(2012) Richy C.Y. Chen et al.   HEPATOLOGY

Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice

(2012) Masanobu Tsuda et al.   HEPATOLOGY

T-bet+ Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2

(2012) Meghan A. Koch et al.   IMMUNITY

Human Prostate Tumor Antigen-Specific CD8+ Regulatory T Cells Are Inhibited by CTLA-4 or IL-35 Blockade

(2012) B. M. Olson et al.   JOURNAL OF IMMUNOLOGY

Increased Th17 and Regulatory T Cell Responses in EBV-Induced Gene 3-Deficient Mice Lead to Marginally Enhanced Development of Autoimmune Encephalomyelitis

(2012) J.-Q. Liu et al.   JOURNAL OF IMMUNOLOGY

From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines

(2012) Jacques Banchereau et al.   NATURE IMMUNOLOGY

The composition and signaling of the IL-35 receptor are unconventional

(2012) Lauren W Collison et al.   NATURE IMMUNOLOGY

Interleukin-35 Mediates Mucosal Immune Responses That Protect Against T-Cell–Dependent Colitis

(2011) Stefan Wirtz et al.   GASTROENTEROLOGY

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations

(2011) Lara Bossini-Castillo et al.   HUMAN MOLECULAR GENETICS

IL-35 Stimulation of CD39+ Regulatory T Cells Confers Protection against Collagen II-Induced Arthritis via the Production of IL-10

(2010) I. Kochetkova et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study identifies variants in the MHC class I, IL10 and IL23R-IL12RB2 regions associated with Behçet's disease

(2010) Elaine F Remmers et al.   NATURE GENETICS

IL-35-mediated induction of a potent regulatory T cell population

(2010) Lauren W Collison et al.   NATURE IMMUNOLOGY

Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor β receptor type II mice

(2009) Katsunori Yoshida et al.   HEPATOLOGY

Interleukin-35: odd one out or part of the family?

(2009) Lauren W. Collison et al.   IMMUNOLOGICAL REVIEWS

Genetic epistasis of IL23/IL17 pathway genes in Crohnʼs disease

(2009) Dermot P.B. McGovern et al.   INFLAMMATORY BOWEL DISEASES

IL-27 Is a Key Regulator of IL-10 and IL-17 Production by Human CD4+ T Cells

(2009) G. Murugaiyan et al.   JOURNAL OF IMMUNOLOGY

Primary Biliary Cirrhosis Associated withHLA, IL12A,andIL12RB2Variants

(2009) Gideon M. Hirschfield et al.   NEW ENGLAND JOURNAL OF MEDICINE