IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: Implications for therapy

Increased IL-23 and IL-17 expression by peripheral blood cells of patients with primary biliary cirrhosis

(2013) Cheng Qian et al.   CYTOKINE

Th17 Cells Induce Th1-Polarizing Monocyte-Derived Dendritic Cells

(2013) M. G. Davidson et al.   JOURNAL OF IMMUNOLOGY

Identification of Potential Cytokine Pathways for Therapeutic Intervention in Murine Primary Biliary Cirrhosis

(2013) Kazuhito Kawata et al.   PLoS One

A balance of interleukin-12 and -23 in cancer

(2013) Shin Foong Ngiow et al.   TRENDS IN IMMUNOLOGY

Epitope-specific anti-nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine-dependent

(2012) C-Y. Yang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Th17 Cells Regulate Liver Fibrosis by Targeting Multiple Cell Types: Many Birds With One Stone

(2012) Bin Gao et al.   GASTROENTEROLOGY

The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17a deleted dominant negative form of transforming growth factor beta receptor type ii mice

(2012) Yugo Ando et al.   HEPATOLOGY

Deletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice

(2012) Masanobu Tsuda et al.   HEPATOLOGY

Genetic variations in interleukin-12 related genes in immune-mediated diseases

(2012) R.L.J. van Wanrooij et al.   JOURNAL OF AUTOIMMUNITY

Towards common denominators in primary biliary cirrhosis: The role of IL-12

(2011) Ana Lleo et al.   JOURNAL OF HEPATOLOGY

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

(2011) George F Mells et al.   NATURE GENETICS

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

(2010) Xiangdong Liu et al.   NATURE GENETICS

Imbalance between T helper type 17 and T regulatory cells in patients with primary biliary cirrhosis: the serum cytokine profile and peripheral cell population

(2009) G. Rong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Periductal interleukin-17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis

(2009) K. Harada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

KIF5B-ALK, a Novel Fusion Oncokinase Identified by an Immunohistochemistry-based Diagnostic System for ALK-positive Lung Cancer

(2009) K. Takeuchi et al.   CLINICAL CANCER RESEARCH

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

(2009) S. Brand   GUT

Toward the molecular dissection of primary biliary cirrhosis

(2009) Gideon M. Hirschfield et al.   HEPATOLOGY

Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor β receptor type II mice

(2009) Katsunori Yoshida et al.   HEPATOLOGY

Primary Biliary Cirrhosis Associated withHLA, IL12A,andIL12RB2Variants

(2009) Gideon M. Hirschfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease

(2008) Kanji Wakabayashi et al.   HEPATOLOGY

Role of Th1 and Th17 cells in organ-specific autoimmunity

(2008) Valérie Dardalhon et al.   JOURNAL OF AUTOIMMUNITY

Hepatic IL-17 responses in human and murine primary biliary cirrhosis

(2008) Ruth Y.Z. Lan et al.   JOURNAL OF AUTOIMMUNITY

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

(2008) Dror Luger et al.   JOURNAL OF EXPERIMENTAL MEDICINE