The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling

Transforming Growth Factor-β Family Ligands Can Function as Antagonists by Competing for Type II Receptor Binding

(2016) Senem Aykul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FGF2 inhibits endothelial–mesenchymal transition through microRNA-20a-mediated repression of canonical TGF-β signaling

(2016) Ana C. P. Correia et al.   JOURNAL OF CELL SCIENCE

Differential activation of noncanonical SMAD2/SMAD3 signaling by bone morphogenetic proteins causes disproportionate induction of hyaluronan production in immortalized human granulosa cells

(2016) Han Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Loss of BMPR2 leads to high bone mass due to increased osteoblast activity

(2015) J. W. Lowery et al.   JOURNAL OF CELL SCIENCE

Neofunction of ACVR1 in fibrodysplasia ossificans progressiva

(2015) Kyosuke Hino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ACVR1 R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A

(2015) Sarah J. Hatsell et al.   Science Translational Medicine

New Protocol to Optimize iPS Cells for Genome Analysis of Fibrodysplasia Ossificans Progressiva

(2015) Yoshihisa Matsumoto et al.   STEM CELLS

Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva

(2015) Jie Cai et al.   Stem Cell Reports

Fibrogenic Cell Plasticity Blunts Tissue Regeneration and Aggravates Muscular Dystrophy

(2015) Patrizia Pessina et al.   Stem Cell Reports

TGF-  Signaling Mediates Endothelial-to-Mesenchymal Transition (EndMT) During Vein Graft Remodeling

(2014) B. C. Cooley et al.   Science Translational Medicine

Concise Review: Evidence for CD34 as a Common Marker for Diverse Progenitors

(2014) Laura E. Sidney et al.   STEM CELLS

Alk2 Regulates Early Chondrogenic Fate in Fibrodysplasia Ossificans Progressiva Heterotopic Endochondral Ossification

(2014) Andria L. Culbert et al.   STEM CELLS

Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia

(2014) C. Ian Spencer et al.   Stem Cell Reports

Always cleave up your mess: targeting collagen degradation to treat tissue fibrosis

(2013) William McKleroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development

(2013) Alisha Holtzhausen et al.   FASEB JOURNAL

EndMT contributes to the onset and progression of cerebral cavernous malformations

(2013) Luigi Maddaluno et al.   NATURE

Role of the extracellular matrix in regulating stem cell fate

(2013) Fiona M. Watt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation

(2013) Yoshihisa Matsumoto et al.   Orphanet Journal of Rare Diseases

Heterotopic ossification after central nervous system trauma

(2013) M. P. Sullivan et al.   Bone & Joint Research

Multipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification

(2012) Michael N Wosczyna et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Correction: Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation

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Limited Gene Expression Variation in Human Embryonic Stem Cell and Induced Pluripotent Stem Cell-Derived Endothelial Cells

(2012) Mark P. White et al.   STEM CELLS

Activin A inhibits vascular endothelial cell growth and suppresses tumour angiogenesis in gastric cancer

(2011) H Kaneda et al.   BRITISH JOURNAL OF CANCER

Fibrodysplasia Ossificans Progressiva: Clinical and Genetic Aspects

(2011) Robert J Pignolo et al.   Orphanet Journal of Rare Diseases

Conversion of vascular endothelial cells into multipotent stem-like cells

(2010) Damian Medici et al.   NATURE MEDICINE

Clinical Significance of the Heterotopic Ossification After Total Hip Arthroplasty

(2010) Mirjana Kocic et al.   ORTHOPEDICS

Molecular mechanisms of endothelial differentiation

(2010) Alex Le Bras et al.   VASCULAR MEDICINE

Identification of Progenitor Cells That Contribute to Heterotopic Skeletogenesis

(2009) Vitali Y Lounev et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Circulating Osteogenic Precursor Cells in Heterotopic Bone Formation

(2009) Robin K. Suda et al.   STEM CELLS

High-Density Lipoproteins Affect Endothelial BMP-Signaling by Modulating Expression of the Activin-Like Kinase Receptor 1 and 2

(2008) Yucheng Yao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fibrodysplasia ossificans progressiva

(2008) Frederick S. Kaplan et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1

(2008) Frederick S. Kaplan et al.   HUMAN MUTATION

BMP type I receptor inhibition reduces heterotopic ossification

(2008) Paul B Yu et al.   NATURE MEDICINE