Purine Pathway Implicated in Mechanism of Resistance to Aspirin Therapy: Pharmacometabolomics-Informed Pharmacogenomics

Extracellular guanosine regulates extracellular adenosine levels

(2012) Edwin K. Jackson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Merging pharmacometabolomics with pharmacogenomics using ‘1000 Genomes’ single-nucleotide polymorphism imputation

(2012) Ryan Abo et al.   Pharmacogenetics and Genomics

Metabolomics Reveals Amino Acids Contribute to Variation in Response to Simvastatin Treatment

(2012) Miles Trupp et al.   PLoS One

Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment

(2011) Rima Kaddurah-Daouk et al.   PLoS One

Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept

(2011) R Kaddurah-Daouk et al.   Translational Psychiatry

Adenosine Derived From ADP Can Contribute to Inhibition of Platelet Aggregation in the Presence of a P2Y 12 Antagonist

(2010) David Iyú et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Association of a Peripheral Blood Metabolic Profile With Coronary Artery Disease and Risk of Subsequent Cardiovascular Events

(2010) Svati H. Shah et al.   Circulation-Cardiovascular Genetics

Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics

(2010) Y Ji et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study

(2010) Rima Kaddurah-Daouk et al.   Metabolomics

Aspirin Resistance in Healthy Drug-Naive Men Versus Women (from the Heredity and Phenotype Intervention Heart Study)

(2009) Haiqing Shen et al.   AMERICAN JOURNAL OF CARDIOLOGY

Adenosine: An Old Drug Newly Discovered

(2009) Holger K. Eltzschig   ANESTHESIOLOGY

Association of Cytochrome P450 2C19 Genotype With the Antiplatelet Effect and Clinical Efficacy of Clopidogrel Therapy

(2009) Alan R. Shuldiner   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The genetic response to short-term interventions affecting cardiovascular function: Rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study

(2008) Braxton D. Mitchell et al.   AMERICAN HEART JOURNAL

Pharmacogenetics of aspirin resistance: a comprehensive systematic review

(2008) Timothy Goodman et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Metabolomics: A Global Biochemical Approach to the Study of Central Nervous System Diseases

(2008) Rima Kaddurah-Daouk et al.   NEUROPSYCHOPHARMACOLOGY

Quality control for plant metabolomics: reporting MSI-compliant studies

(2008) Oliver Fiehn et al.   PLANT JOURNAL

Effect of adenosine A2 receptor stimulation on platelet activation–aggregation: Differences between canine and human models

(2007) Matthew D. Linden et al.   THROMBOSIS RESEARCH