Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo

Merging pharmacometabolomics with pharmacogenomics using ‘1000 Genomes’ single-nucleotide polymorphism imputation

(2012) Ryan Abo et al.   Pharmacogenetics and Genomics

Metabolomics Reveals Amino Acids Contribute to Variation in Response to Simvastatin Treatment

(2012) Miles Trupp et al.   PLoS One

Cortisol and depression: three questions for psychiatry

(2012) J. Herbert   PSYCHOLOGICAL MEDICINE

Metscape 2 bioinformatics tool for the analysis and visualization of metabolomics and gene expression data

(2011) Alla Karnovsky et al.   BIOINFORMATICS

The volatile compound BinBase mass spectral database

(2011) Kirsten Skogerson et al.   BMC BIOINFORMATICS

New Strategies in the Development of Antidepressants: Towards the Modulation of Neuroplasticity Pathways

(2011) Rebeca Vidal et al.   CURRENT PHARMACEUTICAL DESIGN

A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5

(2011) S. J. Tudhope et al.   DIABETES

Serotonin modulates hepatic 6-phosphofructo-1-kinase in an insulin synergistic manner

(2011) Wagner Santos Coelho et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Associations of polyunsaturated fatty acids with residual depression or anxiety in older people with major depression

(2011) Ayesha Jadoon et al.   JOURNAL OF AFFECTIVE DISORDERS

Omega-3 Fatty Acid Augmentation of Citalopram Treatment for Patients With Major Depressive Disorder

(2011) Lev Gertsik et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Administration of memantine and imipramine alters mitochondrial respiratory chain and creatine kinase activities in rat brain

(2011) Gislaine Z. Réus et al.   JOURNAL OF NEURAL TRANSMISSION

The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression

(2011) Martin A. Kohli et al.   NEURON

Synaptoproteomics of learned helpless rats involve energy metabolism and cellular remodeling pathways in depressive-like behavior and antidepressant response

(2011) Alessandra Mallei et al.   NEUROPHARMACOLOGY

Metabolite profiling of antidepressant drug action reveals novel drug targets beyond monoamine elevation

(2011) C Webhofer et al.   Translational Psychiatry

Evaluation of Krebs cycle enzymes in the brain of rats after chronic administration of antidepressants

(2010) Giselli Scaini et al.   BRAIN RESEARCH BULLETIN

Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics

(2010) Y Ji et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Sertraline increases extracellular levels not only of serotonin, but also of dopamine in the nucleus accumbens and striatum of rats

(2010) Yuji Kitaichi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Antidepressant Sertraline Targets Intracellular Vesiculogenic Membranes in Yeast

(2010) M. M. Rainey et al.   GENETICS

MRP1 Polymorphisms Associated With Citalopram Response in Patients With Major Depression

(2010) Sung Hee Lee et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Metabolomic Differences in Heart Failure Patients With and Without Major Depression

(2010) David C. Steffens et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Antidepressants act on glial cells: SSRIs and serotonin elicit astrocyte calcium signaling in the mouse prefrontal cortex

(2010) Carola G. Schipke et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Genome-wide association study of major depressive disorder: new results, meta-analysis and lessons learned

(2010) N R Wray et al.   MOLECULAR PSYCHIATRY

5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional ‘serotonin-specific reuptake inhibitors’

(2010) Shiquen Zhang et al.   Neuron Glia Biology

Treatment with olanzapine, fluoxetine and olanzapine/fluoxetine alters citrate synthase activity in rat brain

(2010) Fabiano R. Agostinho et al.   NEUROSCIENCE LETTERS

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis

(2010) Yann S. Mineur et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

(2009)   AMERICAN JOURNAL OF PSYCHIATRY

FiehnLib: Mass Spectral and Retention Index Libraries for Metabolomics Based on Quadrupole and Time-of-Flight Gas Chromatography/Mass Spectrometry

(2009) Tobias Kind et al.   ANALYTICAL CHEMISTRY

Major Depressive Disorder and Hypothalamic-Pituitary-Adrenal Axis Activity

(2009) Sophie A. Vreeburg et al.   ARCHIVES OF GENERAL PSYCHIATRY

Effects of olanzapine, fluoxetine and olanzapine/fluoxetine on creatine kinase activity in rat brain

(2009) Fabiano R. Agostinho et al.   BRAIN RESEARCH BULLETIN

Brain creatine kinase activity is increased by chronic administration of paroxetine

(2009) Patricia M. Santos et al.   BRAIN RESEARCH BULLETIN

Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids?

(2009) Lynette Hui-Wen Lee et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Rethinking depression and the actions of antidepressants: Uncovering the links between the neural and behavioral elements

(2009) Martin M. Katz et al.   JOURNAL OF AFFECTIVE DISORDERS

Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures

(2009) Zheng Zhou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human gut microbiome adopts an alternative state following small bowel transplantation

(2009) A. L. Hartman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary linoleic and oleic fatty acids in relation to severe depressed mood: 10 years follow-up of a national cohort

(2009) Allen R. Wolfe et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The STAR*D Trial: Revealing the Need for Better Treatments

(2009) Thomas Insel et al.   PSYCHIATRIC SERVICES

Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation

(2009) Baoman Li et al.   PSYCHOPHARMACOLOGY

Metabolomics: A Global Biochemical Approach to Drug Response and Disease

(2008) Rima Kaddurah-Daouk et al.   Annual Review of Pharmacology and Toxicology

From the Selective Serotonin Transporter Inhibitor Citalopram to the Selective Norepinephrine Transporter Inhibitor Talopram: Synthesis and Structure−Activity Relationship Studies

(2008) Jonas N. N. Eildal et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metabolomics: A Global Biochemical Approach to the Study of Central Nervous System Diseases

(2008) Rima Kaddurah-Daouk et al.   NEUROPSYCHOPHARMACOLOGY