Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks
Authors
Keywords
-
Journal
Nature Communications
Volume 7, Issue -, Pages 12889
Publisher
Springer Nature
Online
2016-09-19
DOI
10.1038/ncomms12889
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks
- (2016) Cyril Ribeyre et al. Cell Reports
- Interplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End Resection
- (2015) Danielle S. Krasner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Systematic E2 screening reveals a UBE2D–RNF138–CtIP axis promoting DNA repair
- (2015) Christine K. Schmidt et al. NATURE CELL BIOLOGY
- The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice
- (2015) Ismail Hassan Ismail et al. NATURE CELL BIOLOGY
- ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1
- (2015) Amanda W. Kijas et al. NUCLEIC ACIDS RESEARCH
- PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
- (2015) T. Ochi et al. SCIENCE
- Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway
- (2015) Mengtan Xing et al. Nature Communications
- Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites
- (2015) Jessica S. Brown et al. Cell Reports
- DNA double strand break repair pathway choice: a chromatin based decision?
- (2015) T Clouaire et al. Nucleus
- DNA double strand break repair pathway choice: a chromatin based decision?
- (2015) T Clouaire et al. Nucleus
- Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1
- (2014) Olivia Barton et al. JOURNAL OF CELL BIOLOGY
- CtIP Maintains Stability at Common Fragile Sites and Inverted Repeats by End Resection-Independent Endonuclease Activity
- (2014) Hailong Wang et al. MOLECULAR CELL
- Catalytic and Noncatalytic Roles of the CtIP Endonuclease in Double-Strand Break End Resection
- (2014) Nodar Makharashvili et al. MOLECULAR CELL
- Sae2 promotes dsDNA endonuclease activity within Mre11–Rad50–Xrs2 to resect DNA breaks
- (2014) Elda Cannavo et al. NATURE
- DNA Dynamics during Early Double-Strand Break Processing Revealed by Non-Intrusive Imaging of Living Cells
- (2014) Hicham Saad et al. PLoS Genetics
- The complexity of DNA double strand breaks is a critical factor enhancing end-resection
- (2013) Hirohiko Yajima et al. DNA REPAIR
- DNA structure-specific priming of ATR activation by DNA-PKcs
- (2013) Sophie Vidal-Eychenié et al. JOURNAL OF CELL BIOLOGY
- A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
- (2013) Sébastien Britton et al. JOURNAL OF CELL BIOLOGY
- DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
- (2013) Atsushi Shibata et al. MOLECULAR CELL
- Causes and consequences of replication stress
- (2013) Michelle K. Zeman et al. NATURE CELL BIOLOGY
- The ATM protein kinase: regulating the cellular response to genotoxic stress and more
- (2013) Yosef Shiloh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase
- (2013) E. M. Kass et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Ku Heterodimer and the Metabolism of Single-Ended DNA Double-Strand Breaks
- (2013) Alessia Balestrini et al. Cell Reports
- A high-throughput, flow cytometry-based method to quantify DNA-end resection in mammalian cells
- (2012) Josep V. Forment et al. CYTOMETRY PART A
- The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1
- (2012) Soo-Hyun Yang et al. EMBO JOURNAL
- Loss of ATM kinase activity leads to embryonic lethality in mice
- (2012) Jeremy A. Daniel et al. JOURNAL OF CELL BIOLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Topoisomerase I poisoning results in PARP-mediated replication fork reversal
- (2012) Arnab Ray Chaudhuri et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ATM Protein-dependent Phosphorylation of Rad50 Protein Regulates DNA Repair and Cell Cycle Control
- (2011) Magtouf Gatei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human Ku70/80 Protein Blocks Exonuclease 1-mediated DNA Resection in the Presence of Human Mre11 or Mre11/Rad50 Protein Complex
- (2011) Jingxin Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional Interplay of the Mre11 Nuclease and Ku in the Response to Replication-Associated DNA Damage
- (2011) S. S. Foster et al. MOLECULAR AND CELLULAR BIOLOGY
- Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
- (2011) Valerie Garcia et al. NATURE
- Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
- (2011) Qiao Cheng et al. NUCLEIC ACIDS RESEARCH
- Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells
- (2011) A. G. Patel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Release of Ku and MRN from DNA Ends by Mre11 Nuclease Activity and Ctp1 Is Required for Homologous Recombination Repair of Double-Strand Breaks
- (2011) Petra Langerak et al. PLoS Genetics
- The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
- (2010) Michael R. Lieber Annual Review of Biochemistry
- Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2
- (2010) Eleni P Mimitou et al. EMBO JOURNAL
- Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
- (2010) Eun Yong Shim et al. EMBO JOURNAL
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1
- (2010) Verena Quennet et al. NUCLEIC ACIDS RESEARCH
- Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
- (2009) Brandi L. Mahaney et al. BIOCHEMICAL JOURNAL
- Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
- (2009) Pablo Huertas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- The emerging role of nuclear architecture in DNA repair and genome maintenance
- (2009) Tom Misteli et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mre11 Nuclease Activity Has Essential Roles in DNA Repair and Genomic Stability Distinct from ATM Activation
- (2008) Jeffrey Buis et al. CELL
- Ku80 removal from DNA through double strand break–induced ubiquitylation
- (2008) Lisa Postow et al. JOURNAL OF CELL BIOLOGY
- CDK targets Sae2 to control DNA-end resection and homologous recombination
- (2008) Pablo Huertas et al. NATURE
- A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex
- (2008) Aude Dupré et al. Nature Chemical Biology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation