The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice

Systematic E2 screening reveals a UBE2D–RNF138–CtIP axis promoting DNA repair

(2015) Christine K. Schmidt et al.   NATURE CELL BIOLOGY

A Novel Gene RNF138 Expressed in Human Gliomas and Its Function in the Glioma Cell Line U251

(2015) You-xin Zhou et al.   Analytical Cellular Pathology

Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes

(2014) Sachin Katyal et al.   NATURE NEUROSCIENCE

A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair

(2013) Sébastien Britton et al.   JOURNAL OF CELL BIOLOGY

Persistently bound Ku at DNA ends attenuates DNA end resection and homologous recombination

(2012) Zhengping Shao et al.   DNA REPAIR

Quantitative Live Cell Imaging Reveals a Gradual Shift between DNA Repair Mechanisms and a Maximal Use of HR in Mid S Phase

(2012) Ketki Karanam et al.   MOLECULAR CELL

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

The E3 ligase RNF8 regulates KU80 removal and NHEJ repair

(2012) Lin Feng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage

(2012) Ismail Hassan Ismail et al.   NUCLEIC ACIDS RESEARCH

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks

(2011) Qiao Cheng et al.   NUCLEIC ACIDS RESEARCH

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks

(2010) Eun Yong Shim et al.   EMBO JOURNAL

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

At Loose Ends: Resecting a Double-Strand Break

(2009) Kara A. Bernstein et al.   CELL

DNA Repair in Mammalian Cells

(2009) B. Pardo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of mammalian Mre11 in classical and alternative nonhomologous end joining

(2009) Anyong Xie et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain

(2008) Ana Lucia Giannini et al.   BIOCHEMICAL JOURNAL

Recruitment and Dissociation of Nonhomologous End Joining Proteins at a DNA Double-Strand Break in Saccharomyces cerevisiae

(2008) D. Wu et al.   GENETICS

Ku80 removal from DNA through double strand break–induced ubiquitylation

(2008) Lisa Postow et al.   JOURNAL OF CELL BIOLOGY

Regulation of DNA repair throughout the cell cycle

(2008) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

(2008) Wei Li et al.   PLoS One