DNA structure-specific priming of ATR activation by DNA-PKcs

Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover

(2013) Barnabas Szakal et al.   EMBO JOURNAL

Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates

(2013) Kai J. Neelsen et al.   JOURNAL OF CELL BIOLOGY

Topoisomerase I poisoning results in PARP-mediated replication fork reversal

(2012) Arnab Ray Chaudhuri et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress

(2012) S. Liu et al.   NUCLEIC ACIDS RESEARCH

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

(2011) Luis I Toledo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA-PK-Dependent RPA2 Hyperphosphorylation Facilitates DNA Repair and Suppresses Sister Chromatid Exchange

(2011) Hungjiun Liaw et al.   PLoS One

More forks on the road to replication stress recovery

(2011) C. Allen et al.   Journal of Molecular Cell Biology

The role of RPA2 phosphorylation in homologous recombination in response to replication arrest

(2010) Wei Shi et al.   CARCINOGENESIS

Continued primer synthesis at stalled replication forks contributes to checkpoint activation

(2010) Christopher Van et al.   JOURNAL OF CELL BIOLOGY

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

(2010) J.-H. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mre11-Rad50-Nbs1 Complex Mediates Activation of TopBP1 by ATM

(2009) Hae Yong Yoo et al.   MOLECULAR BIOLOGY OF THE CELL

Single-Stranded DNA Orchestrates an ATM-to-ATR Switch at DNA Breaks

(2009) Bunsyo Shiotani et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Remodeling of DNA replication structures by the branch point translocase FANCM

(2008) K. Gari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA