Seeing Is Believing: Visualizing Transcriptional Dynamics in Single Cells

Genome Architecture: Domain Organization of Interphase Chromosomes

(2013) Wendy A. Bickmore et al.   CELL

Zooming in on single active genes in living mammalian cells

(2013) Sharon Yunger et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Single Cell Analysis of RNA-mediated Histone H3.3 Recruitment to a Cytomegalovirus Promoter-regulated Transcription Site

(2013) Alyshia Newhart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sp100A promotes chromatin decondensation at a cytomegalovirus-promoter–regulated transcription site

(2013) Alyshia Newhart et al.   MOLECULAR BIOLOGY OF THE CELL

Single-molecule imaging of transcription factor binding to DNA in live mammalian cells

(2013) J Christof M Gebhardt et al.   NATURE METHODS

Quantifying the transcriptional output of single alleles in single living mammalian cells

(2013) Sharon Yunger et al.   Nature Protocols

Eukaryotic transcriptional dynamics: from single molecules to cell populations

(2013) Antoine Coulon et al.   NATURE REVIEWS GENETICS

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

(2013) Jiangbo Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells

(2013) I. I. Cisse et al.   SCIENCE

Pluripotency in 3D: genome organization in pluripotent cells

(2012) Matthew Denholtz et al.   CURRENT OPINION IN CELL BIOLOGY

Nuclear bodies: multifunctional companions of the genome

(2012) Miroslav Dundr   CURRENT OPINION IN CELL BIOLOGY

 -Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration

(2012) Z. B. Katz et al.   GENES & DEVELOPMENT

Acute promyelocytic leukemia, arsenic, and PML bodies

(2012) Hugues de Thé et al.   JOURNAL OF CELL BIOLOGY

Single-cell analysis of Daxx and ATRX-dependent transcriptional repression

(2012) Alyshia Newhart et al.   JOURNAL OF CELL SCIENCE

Regulation of alphaherpesvirus infections by the ICP0 family of proteins

(2012) C. Boutell et al.   JOURNAL OF GENERAL VIROLOGY

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

(2012) Jeremy Schwartzentruber et al.   NATURE

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

(2012) Jan J. Molenaar et al.   NATURE

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

(2012) Gang Wu et al.   NATURE GENETICS

Single-molecule analysis of gene expression using two-color RNA labeling in live yeast

(2012) Sami Hocine et al.   NATURE METHODS

Modern fluorescent proteins and imaging technologies to study gene expression, nuclear localization, and dynamics

(2011) Bin Wu et al.   CURRENT OPINION IN CELL BIOLOGY

Fast transcription rates of RNA polymerase II in human cells

(2011) Paolo Maiuri et al.   EMBO REPORTS

Nucleation of nuclear bodies by RNA

(2011) Sergey P. Shevtsov et al.   NATURE CELL BIOLOGY

Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation

(2011) Rui Zhao et al.   NATURE CELL BIOLOGY

Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3′ end of human genes

(2011) Sandra Bento Martins et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

Real-Time Observation of Transcription Initiation and Elongation on an Endogenous Yeast Gene

(2011) D. R. Larson et al.   SCIENCE

Biogenesis and function of nuclear bodies

(2011) Yuntao S. Mao et al.   TRENDS IN GENETICS

The In Vivo Kinetics of RNA Polymerase II Elongation during Co-Transcriptional Splicing

(2011) Yehuda Brody et al.   PLOS BIOLOGY

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

The life of an mRNA in space and time

(2010) Y. Ben-Ari et al.   JOURNAL OF CELL SCIENCE

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs

(2010) Yuntao S. Mao et al.   NATURE CELL BIOLOGY

Single-allele analysis of transcription kinetics in living mammalian cells

(2010) Sharon Yunger et al.   NATURE METHODS

Single Cell Analysis of Transcriptional Activation Dynamics

(2010) Ilona U. Rafalska-Metcalf et al.   PLoS One

The Nucleolus

(2010) T. Pederson   Cold Spring Harbor Perspectives in Biology

PML Nuclear Bodies

(2010) V. Lallemand-Breitenbach et al.   Cold Spring Harbor Perspectives in Biology

Higher-order Genome Organization in Human Disease

(2010) T. Misteli   Cold Spring Harbor Perspectives in Biology

Biogenesis of Nuclear Bodies

(2010) M. Dundr et al.   Cold Spring Harbor Perspectives in Biology

Transcription-dependent silencing of inducible convergent transgenes in transgenic mice

(2010) Fernando J Calero-Nieto et al.   Epigenetics & Chromatin

Imaging Transcription in Living Cells

(2009) Xavier Darzacq et al.   Annual Review of Biophysics

Transcription Dynamics

(2009) Gordon L. Hager et al.   MOLECULAR CELL

Nuclear order out of chaos

(2008) Tom Misteli   NATURE