Stratification and therapeutic potential of PML in metastatic breast cancer

mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance

(2016) Laura Garros-Regulez et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

SOX9-mediated upregulation of LGR5 is important for glioblastoma tumorigenicity

(2015) Koji Hiraoka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sox9 Controls Self-Renewal of Oncogene Targeted Cells and Links Tumor Initiation and Invasion

(2015) Jean-Christophe Larsimont et al.   Cell Stem Cell

SOX9 Maintains Reserve Stem Cells and Preserves Radioresistance in Mouse Small Intestine

(2015) Kyle C. Roche et al.   GASTROENTEROLOGY

Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis

(2015) Milica Pavlovic et al.   JNCI-Journal of the National Cancer Institute

Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice

(2015) Rene C. Adam et al.   NATURE

SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma

(2015) S Luanpitpong et al.   ONCOGENE

Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis

(2015) Milica Pavlovic et al.   JNCI-Journal of the National Cancer Institute

The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells

(2014) Gautam K Malhotra et al.   BMC DEVELOPMENTAL BIOLOGY

PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation ofMMP2

(2014) Hong-Yi Kuo et al.   CELL CYCLE

RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation

(2014) M. Morales et al.   EMBO Molecular Medicine

Sox2 promotes tamoxifen resistance in breast cancer cells

(2013) Marco Piva et al.   EMBO Molecular Medicine

SOX9 Regulates Low Density Lipoprotein Receptor-related Protein 6 (LRP6) and T-cell Factor 4 (TCF4) Expression and Wnt/β-catenin Activation in Breast Cancer

(2013) Hongyun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PML: Not all about Tumor Suppression

(2013) Natalia Martin-Martin et al.   Frontiers in Oncology

Oncogenicity of the Developmental Transcription Factor Sox9

(2012) A. Matheu et al.   CANCER RESEARCH

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

(2012) Wenjun Guo et al.   CELL

Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors

(2012) J. Wang et al.   GENOME RESEARCH

Interleukin 6 Signaling Regulates Promyelocytic Leukemia Protein Gene Expression in Human Normal and Cancer Cells

(2012) Sona Hubackova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The evolving concept of cancer and metastasis stem cells

(2012) Irène Baccelli et al.   JOURNAL OF CELL BIOLOGY

A metabolic prosurvival role for PML in breast cancer

(2012) Arkaitz Carracedo et al.   JOURNAL OF CLINICAL INVESTIGATION

Architecture of the human regulatory network derived from ENCODE data

(2012) Mark B. Gerstein et al.   NATURE

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance

(2012) Keisuke Ito et al.   NATURE MEDICINE

Factorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium

(2012) J. Wang et al.   NUCLEIC ACIDS RESEARCH

The Evolving War on Cancer

(2011) Daniel A. Haber et al.   CELL

Single-vector inducible lentiviral RNAi system for oncology target validation

(2011) Dmitri Wiederschain et al.   CELL CYCLE

The nuclear bodies inside out: PML conquers the cytoplasm

(2011) Arkaitz Carracedo et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of E2Fs and senescence by PML nuclear bodies

(2011) M. Vernier et al.   GENES & DEVELOPMENT

Validation of an immunohistochemical signature predictive of 8-year outcome for patients with breast carcinoma

(2011) Colette Charpin et al.   INTERNATIONAL JOURNAL OF CANCER

Modeling metastasis in the mouse

(2010) Paula D Bos et al.   CURRENT OPINION IN PHARMACOLOGY

Gene Pathways Associated With Prognosis and Chemotherapy Sensitivity in Molecular Subtypes of Breast Cancer

(2010) Takayuki Iwamoto et al.   JNCI-Journal of the National Cancer Institute

Clinical implementation of the intrinsic subtypes of breast cancer

(2010) Charles M Perou et al.   LANCET ONCOLOGY

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

SOX9 induces and maintains neural stem cells

(2010) Charlotte E Scott et al.   NATURE NEUROSCIENCE

Prognostic Applications of Gene Expression Signatures in Breast Cancer

(2010) Nicola Normanno et al.   ONCOLOGY

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

BASH: a tool for managing BeadArray spatial artefacts

(2008) J. M. Cairns et al.   BIOINFORMATICS

Oncogene Addiction

(2008) I. B. Weinstein et al.   CANCER RESEARCH

PML targeting eradicates quiescent leukaemia-initiating cells

(2008) Keisuke Ito et al.   NATURE

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Molecular Basis of Metastasis

(2008) Anne C. Chiang et al.   NEW ENGLAND JOURNAL OF MEDICINE