PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation ofMMP2

Nuclear Epidermal Growth Factor Receptor Is a Functional Molecular Target in Triple-Negative Breast Cancer

(2014) T. M. Brand et al.   MOLECULAR CANCER THERAPEUTICS

The PML isoform IV is a negative regulator of nuclear EGFR’s transcriptional activity in lung cancer

(2013) Hong-Yi Kuo et al.   CARCINOGENESIS

Nuclear EGFR protein expression predicts poor survival in early stage non-small cell lung cancer

(2013) Anne M. Traynor et al.   LUNG CANCER

PML-mediated signaling and its role in cancer stem cells

(2013) W Zhou et al.   ONCOGENE

Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking

(2013) Y Du et al.   ONCOGENE

Integrative Analyses Identify Osteopontin, LAMB3 and ITGB1 as Critical Pro-Metastatic Genes for Lung Cancer

(2013) Xiao-Min Wang et al.   PLoS One

Interleukin 6 Signaling Regulates Promyelocytic Leukemia Protein Gene Expression in Human Normal and Cancer Cells

(2012) Sona Hubackova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear EGFR Suppresses Ribonuclease Activity of Polynucleotide Phosphorylase through DNAPK-mediated Phosphorylation at Serine 776

(2012) Yung-Luen Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multidrug-resistant cells overexpressing P-glycoprotein are susceptible to DNA crosslinking agents due to attenuated Src/nuclear EGFR cascade-activated DNA repair activity

(2012) P-C Lee et al.   ONCOGENE

The epigenetic regulator UHRF1 promotes ubiquitination-mediated degradation of the tumor-suppressor protein promyelocytic leukemia protein

(2012) D Guan et al.   ONCOGENE

Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor

(2012) M Iida et al.   ONCOGENE

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression

(2011) Wei-Chien Yuan et al.   CANCER CELL

EGFR Nuclear Translocation Modulates DNA Repair following Cisplatin and Ionizing Radiation Treatment

(2011) G. Liccardi et al.   CANCER RESEARCH

Nuclear Translocation of Epidermal Growth Factor Receptor by Akt-dependent Phosphorylation Enhances Breast Cancer-resistant Protein Expression in Gefitinib-resistant Cells

(2011) Wei-Chien Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport

(2010) Ying-Nai Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EGFR Promotes Lung Tumorigenesis by Activating miR-7 through a Ras/ERK/Myc Pathway That Targets the Ets2 Transcriptional Repressor ERF

(2010) Y.-T. Chou et al.   CANCER RESEARCH

Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654

(2010) Klaus Dittmann et al.   FEBS LETTERS

Promyelocytic Leukemia Protein Controls Cell Migration in Response to Hydrogen Peroxide and Insulin-like Growth Factor-1

(2010) Erin L. Reineke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Translocon Sec61β Localized in the Inner Nuclear Membrane Transports Membrane-embedded EGF Receptor to the Nucleus

(2010) Ying-Nai Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear EGFR in ductal invasive breast cancer: correlation with cyclin-D1 and prognosis

(2010) Ita Hadžisejdić et al.   MODERN PATHOLOGY

AXIN is an essential co-activator for the promyelocytic leukemia protein in p53 activation

(2010) Q Li et al.   ONCOGENE

Nuclear trafficking of the epidermal growth factor receptor family membrane proteins

(2010) Y-N Wang et al.   ONCOGENE

RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus

(2010) L. Huo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dasatinib blocks cetuximab- and radiation-induced nuclear translocation of the epidermal growth factor receptor in head and neck squamous cell carcinoma

(2010) Chunrong Li et al.   RADIOTHERAPY AND ONCOLOGY

Genetic immunotherapy of lung cancer using conditionally replicating adenovirus and adenovirus-interferon-β

(2009) M-Y Park et al.   CANCER GENE THERAPY

Nuclear EGFR contributes to acquired resistance to cetuximab

(2009) C Li et al.   ONCOGENE

Stat3 Is Involved in Angiotensin II-Induced Expression of MMP2 in Gastric Cancer Cells

(2008) Wei Huang et al.   DIGESTIVE DISEASES AND SCIENCES

Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

(2008) Weiya Xia et al.   MOLECULAR CARCINOGENESIS