Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells

HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth

(2015) S Pandolfi et al.   CELL DEATH AND DIFFERENTIATION

Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened

(2015) Annelies Gonnissen et al.   Oncotarget

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

(2015) Ritesh K. Srivastava et al.   Oncotarget

The GANT61, a GLI Inhibitor, Induces Caspase-Independent Apoptosis of SK-N-LO Cells

(2014) Takahiro Matsumoto et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Survivin as a therapeutic target in Sonic hedgehog-driven medulloblastoma

(2014) S N Brun et al.   ONCOGENE

Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy

(2014) Fritz Aberger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

KLF5 strengthens drug resistance of ovarian cancer stem-like cells by regulating survivin expression

(2013) Z. Dong et al.   CELL PROLIFERATION

Transcriptional Regulation of Serine/Threonine Protein Kinase (AKT) Genes by Glioma-associated Oncogene Homolog 1

(2013) Nitin K. Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional regulation of the survivin gene

(2013) Romain Boidot et al.   MOLECULAR BIOLOGY REPORTS

MITF-Independent Pro-Survival Role of BRG1-Containing SWI/SNF Complex in Melanoma Cells

(2013) Lubica Ondrušová et al.   PLoS One

Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells

(2013) Tapati Mazumdar et al.   PLoS One

Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells

(2012) Markus Eberl et al.   EMBO Molecular Medicine

Hedgehog Secretion and Signal Transduction in Vertebrates

(2012) Kaitlyn E. Ryan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hedgehog pathway inhibition and the race against tumor evolution

(2012) Scott X. Atwood et al.   JOURNAL OF CELL BIOLOGY

The Hedgehog processing pathway is required for NSCLC growth and survival

(2012) J Rodriguez-Blanco et al.   ONCOGENE

Hedgehog Signaling in Tumor Cells Facilitates Osteoblast-Enhanced Osteolytic Metastases

(2012) Shamik Das et al.   PLoS One

Genome-Wide Screening Reveals an EMT Molecular Network Mediated by Sonic Hedgehog-Gli1 Signaling in Pancreatic Cancer Cells

(2012) Xuanfu Xu et al.   PLoS One

The Hedgehog Signal Transduction Network

(2012) D. J. Robbins et al.   Science Signaling

Cooperative Hedgehog-EGFR signaling

(2011) Doris Mangelberger   Frontiers in Bioscience-Landmark

Mechanisms of Hedgehog signalling in cancer

(2011) Kieren D. Marini et al.   GROWTH FACTORS

Non-consensus GLI binding sites in Hedgehog target gene regulation

(2010) Martina Winklmayr et al.   BMC MOLECULAR BIOLOGY

DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS

(2010) Matthias Lauth et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Hedgehog Pathway Transcription Factor GLI1 Promotes Malignant Behavior of Cancer Cells by Up-regulating Osteopontin

(2009) Shamik Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the hedgehog-signaling pathway in human cancer and the clinical implications

(2009) L Yang et al.   ONCOGENE

Identification of the gene transcription repressor domain of Gli3

(2008) Robert Tsanev et al.   FEBS LETTERS

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

A paracrine requirement for hedgehog signalling in cancer

(2008) Robert L. Yauch et al.   NATURE

New wirings in the survivin networks

(2008) D C Altieri   ONCOGENE