Crosslinking of DNA-linked ligands to target proteins for enrichment from DNA-encoded libraries

Chemical Biology Probes from Advanced DNA-encoded Libraries

(2016) Hazem Salamon et al.   ACS Chemical Biology

A Set of Organelle-Localizable Reactive Molecules for Mitochondrial Chemical Proteomics in Living Cells and Brain Tissues

(2016) Yuki Yasueda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA tags help the hunt for drugs

(2016) Asher Mullard   NATURE

DNA Encoded Library Selections and Insights Provided by Computational Simulations

(2015) Alexander L. Satz   ACS Chemical Biology

Fidelity by design: Yoctoreactor and binder trap enrichment for small-molecule DNA-encoded libraries and drug discovery

(2015) Peter Blakskjaer et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Selection of DNA-Encoded Small Molecule Libraries Against Unmodified and Non-Immobilized Protein Targets

(2014) Peng Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multivalent Photoaffinity Probe for Labeling Small Molecule Binding Proteins

(2014) Gang Li et al.   BIOCONJUGATE CHEMISTRY

Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7)

(2014) Chakravarthi Simhadri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of Ligand–Target Pairs from Combined Libraries of Small Molecules and Unpurified Protein Targets in Cell Lysates

(2014) Lynn M. McGregor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multiplex single-molecule interaction profiling of DNA-barcoded proteins

(2014) Liangcai Gu et al.   NATURE

Template-directed covalent conjugation of DNA to native antibodies, transferrin and other metal-binding proteins

(2014) Christian B. Rosen et al.   Nature Chemistry

Photoaffinity Labeling of Small-Molecule-Binding Proteins by DNA-Templated Chemistry

(2013) Gang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Organic Chemistry and Applications for Labeling and Engineering in Live-Cell Systems

(2013) Yousuke Takaoka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein interaction discovery using parallel analysis of translated ORFs (PLATO)

(2013) Jian Zhu et al.   NATURE BIOTECHNOLOGY

System-wide identification of RNA-binding proteins by interactome capture

(2013) Alfredo Castello et al.   Nature Protocols

Ligand-Directed Acyl Imidazole Chemistry for Labeling of Membrane-Bound Proteins on Live Cells

(2012) Sho-hei Fujishima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Native FKBP12 Engineering by Ligand-Directed Tosyl Chemistry: Labeling Properties and Application to Photo-Cross-Linking of Protein Complexes in Vitro and in Living Cells

(2012) Tomonori Tamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Proteome profiling reveals potential cellular targets of staurosporine using a clickable cell-permeable probe

(2011) Haibin Shi et al.   CHEMICAL COMMUNICATIONS

Interaction-Dependent PCR: Identification of Ligand−Target Pairs from Libraries of Ligands and Libraries of Targets in a Single Solution-Phase Experiment

(2010) Lynn M. McGregor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Analysis and Optimization of Copper-Catalyzed Azide–Alkyne Cycloaddition for Bioconjugation

(2009) Vu Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-directed tosyl chemistry for protein labeling in vivo

(2009) Shinya Tsukiji et al.   Nature Chemical Biology

Design, synthesis and selection of DNA-encoded small-molecule libraries

(2009) Matthew A Clark et al.   Nature Chemical Biology

Thermodynamic Analysis of Protein Stability and Ligand Binding Using a Chemical Modification- and Mass Spectrometry-Based Strategy

(2008) Graham M. West et al.   ANALYTICAL CHEMISTRY

Selection of Smart Small-Molecule Ligands: The Proof of Principle

(2008) Andrei P. Drabovich et al.   ANALYTICAL CHEMISTRY

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

(2008) Donny D. Licatalosi et al.   NATURE