Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation

Towards the next generation of biomedicines by site-selective conjugation

(2016) Qi-Ying Hu et al.   CHEMICAL SOCIETY REVIEWS

Standing out from the crowd

(2016) Yichao Huang et al.   Nature Chemistry

Fast and selective labeling of N-terminal cysteines at neutral pH via thiazolidino boronate formation

(2016) Anupam Bandyopadhyay et al.   Chemical Science

Water-soluble allyl sulfones for dual site-specific labelling of proteins and cyclic peptides

(2016) Tao Wang et al.   Chemical Science

Orthogonal dual-modification of proteins for the engineering of multivalent protein scaffolds

(2015) Michaela Mühlberg et al.   Beilstein Journal of Organic Chemistry

Click with a boronic acid handle: a neighboring group-assisted click reaction that allows ready secondary functionalization

(2015) Alexander B. Draganov et al.   CHEMICAL COMMUNICATIONS

Rapid formation of a stable boron–nitrogen heterocycle in dilute, neutral aqueous solution for bioorthogonal coupling reactions

(2015) Ozlem Dilek et al.   CHEMICAL COMMUNICATIONS

Advances in Chemical Protein Modification

(2015) Omar Boutureira et al.   CHEMICAL REVIEWS

Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation

(2015) Oleksandr Koniev et al.   CHEMICAL SOCIETY REVIEWS

Iminoboronate Formation Leads to Fast and Reversible Conjugation Chemistry of α-Nucleophiles at Neutral pH

(2015) Anupam Bandyopadhyay et al.   CHEMISTRY-A EUROPEAN JOURNAL

Reversible Lysine Modification on Proteins by Using Functionalized Boronic Acids

(2015) Pedro M. S. D. Cal et al.   CHEMISTRY-A EUROPEAN JOURNAL

Covalent protein modification: the current landscape of residue-specific electrophiles

(2015) D Alexander Shannon et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Boronic acids facilitate rapid oxime condensations at neutral pH

(2015) Pascal Schmidt et al.   Chemical Science

A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy

(2015) Antoine Maruani et al.   Nature Communications

Finding the Right (Bioorthogonal) Chemistry

(2014) David M. Patterson et al.   ACS Chemical Biology

Cysteine-Selective Reactions for Antibody Conjugation

(2014) Pedro M. S. D. Cal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selective Irreversible Chemical Tagging of Cysteine with 3-Arylpropiolonitriles

(2014) Oleksandr Koniev et al.   BIOCONJUGATE CHEMISTRY

Site-Specific Dual Labeling of Proteins by Using Small Orthogonal Tags at Neutral pH

(2014) Jan Grünewald et al.   CHEMBIOCHEM

A rapid, site-selective and efficient route to the dual modification of DARPins

(2014) Paul Moody et al.   CHEMICAL COMMUNICATIONS

Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins

(2014) Amit Sachdeva et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simple and Efficient Strategy for Site-Specific Dual Labeling of Proteins for Single-Molecule Fluorescence Resonance Energy Transfer Analysis

(2013) Jihyo Kim et al.   ANALYTICAL CHEMISTRY

Protein Organic Chemistry and Applications for Labeling and Engineering in Live-Cell Systems

(2013) Yousuke Takaoka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting cancer cells with folic acid–iminoboronate fluorescent conjugates

(2013) Pedro M. S. D. Cal et al.   CHEMICAL COMMUNICATIONS

Simultaneous Dual Protein Labeling Using a Triorthogonal Reagent

(2013) Mohammad Rashidian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-specific chemical modification of antibody fragments using traceless cleavable linkers

(2013) Gonçalo J L Bernardes et al.   Nature Protocols

A biocompatible, highly efficient click reaction and its applications

(2013) Yue Yuan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A novel approach to the site-selective dual labelling of a protein via chemoselective cysteine modification

(2013) Ramiz I. Nathani et al.   Chemical Science

Iminoboronates: A New Strategy for Reversible Protein Modification

(2012) Pedro M. S. D. Cal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Specific Traceless Coupling of Potent Cytotoxic Drugs to Recombinant Antibodies for Pharmacodelivery

(2012) Giulio Casi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Methylsulfonyl Benzothiazole (MSBT): A Selective Protein Thiol Blocking Reagent

(2012) Dehui Zhang et al.   ORGANIC LETTERS

Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis

(2011) John T. Ngo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Choosing an effective protein bioconjugation strategy

(2011) Nicholas Stephanopoulos et al.   Nature Chemical Biology

Methods for converting cysteine to dehydroalanine on peptides and proteins

(2011) Justin M. Chalker et al.   Chemical Science

A Biocompatible Condensation Reaction for the Labeling of Terminal Cysteine Residues on Proteins

(2009) Hongjun Ren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Modification of Proteins at Cysteine: Opportunities in Chemistry and Biology

(2009) Justin M. Chalker et al.   Chemistry-An Asian Journal