Systematic study of the dynamics and half-lives of newly synthesized proteins in human cells

The Biology of Proteostasis in Aging and Disease

(2015) Johnathan Labbadia et al.   Annual Review of Biochemistry

Direct visualization of newly synthesized target proteins in situ

(2015) Susanne tom Dieck et al.   NATURE METHODS

Dysfunction in protein clearance by the proteasome: impact on autoinflammatory diseases

(2015) Anja Brehm et al.   Seminars in Immunopathology

Systematic and site-specific analysis of N-sialoglycosylated proteins on the cell surface by integrating click chemistry and MS-based proteomics

(2015) Weixuan Chen et al.   Chemical Science

Divide and differentiate

(2014) Takao Ishidate et al.   CELL CYCLE

Impaired proteostasis: role in the pathogenesis of diabetes mellitus

(2014) Stéphane Jaisson et al.   DIABETOLOGIA

Mass Spectrometric Analysis of the Cell Surface N-Glycoproteome by Combining Metabolic Labeling and Click Chemistry

(2014) Johanna M. Smeekens et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal

(2014) Thomas S Elliott et al.   NATURE BIOTECHNOLOGY

Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET

(2014) Kaihang Wang et al.   Nature Chemistry

A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells

(2014) Tony Ly et al.   eLife

Chemical reporters for biological discovery

(2013) Markus Grammel et al.   Nature Chemical Biology

QuaNCAT: quantitating proteome dynamics in primary cells

(2013) Andrew J M Howden et al.   NATURE METHODS

Identification of secreted bacterial proteins by noncanonical amino acid tagging

(2013) A. Mahdavi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An integrated view of cyclin E function and regulation

(2012) Ka Tat Siu et al.   CELL CYCLE

Protein Homeostasis, Aging and Alzheimer’s Disease

(2012) Tobias Morawe et al.   MOLECULAR NEUROBIOLOGY

From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions

(2011) Ellen M. Sletten et al.   ACCOUNTS OF CHEMICAL RESEARCH

Bioorthogonal chemical tagging of protein cholesterylation in living cells

(2011) William P. Heal et al.   CHEMICAL COMMUNICATIONS

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Proteome Half-Life Dynamics in Living Human Cells

(2011) E. Eden et al.   SCIENCE

Translational control of cyclins

(2011) Woan-Yuh Tarn et al.   Cell Division

The Roles of Cyclin A2, B1, and B2 in Early and Late Mitotic Events

(2010) Delquin Gong et al.   MOLECULAR BIOLOGY OF THE CELL

Tandem fluorescence imaging of dynamic S-acylation and protein turnover

(2010) M. M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

(2009) Evan T. Powers et al.   Annual Review of Biochemistry

iTRAQ Underestimation in Simple and Complex Mixtures: “The Good, the Bad and the Ugly”

(2009) Saw Yen Ow et al.   JOURNAL OF PROTEOME RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Dynamic Proteomics of Individual Cancer Cells in Response to a Drug

(2008) A. A. Cohen et al.   SCIENCE

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE