A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters

Critical Evaluation and Rate Constants of Chemoselective Ligation Reactions for Stoichiometric Conjugations in Water

(2015) Fumito Saito et al.   ACS Chemical Biology

Chemical Synthesis of O-Glycosylated Human Interleukin-2 by the Reverse Polarity Protection Strategy

(2015) Yuya Asahina et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Protein Synthesis Using a Second-Generation N-Acylurea Linker for the Preparation of Peptide-Thioester Precursors

(2015) Juan B. Blanco-Canosa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptidyl N-alkylcysteine as a peptide thioester surrogate in the native chemical ligation

(2015) Yuya Asahina et al.   TETRAHEDRON LETTERS

Rapid Total Synthesis of DARPin pE59 and Barnase

(2014) Surin K. Mong et al.   CHEMBIOCHEM

Protein Splicing: How Inteins Escape from Precursor Proteins

(2014) Kenneth V. Mills et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reversible Native Chemical Ligation: A Facile Access to Dynamic Covalent Peptides

(2014) Yves Ruff et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Synthesis of Biologically Active Monoglycosylated GM2-Activator Protein Analogue UsingN-Sulfanylethylanilide Peptide

(2013) Kohei Sato et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Bypass of Intein-Catalyzed N-S Acyl Shift in Protein Splicing

(2013) Jens Binschik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic polyubiquitinated  -Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology

(2013) M. Haj-Yahya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments

(2013) Laurent Raibaut et al.   Chemical Science

Insitu thioester formation for protein ligation using α-methylcysteine

(2013) Fabienne Burlina et al.   Chemical Science

Inteins: nature's gift to protein chemists

(2013) Neel H. Shah et al.   Chemical Science

Recent progress in intein research: from mechanism to directed evolution and applications

(2012) Gerrit Volkmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Synthetic Procedure for N-Fmoc Amino Acyl-N-Sulfanylethylaniline Linker as Crypto-Peptide Thioester Precursor with Application to Native Chemical Ligation

(2012) Ken Sakamoto et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Chemical Synthesis of a 304 Amino Acid K48-Linked Tetraubiquitin Protein

(2011) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Chemical Synthesis by Ligation of Peptide Hydrazides

(2011) Ge-Min Fang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Reversible Protection Strategy To Improve Fmoc-SPPS of Peptide Thioesters by the N-Acylurea Approach

(2011) Santosh K. Mahto et al.   CHEMBIOCHEM

N-Sulfanylethylanilide Peptide as a Crypto-Thioester Peptide

(2011) Kohei Sato et al.   CHEMBIOCHEM

Shifting Native Chemical Ligation into Reverse through N→S Acyl Transfer

(2011) Derek Macmillan et al.   ISRAEL JOURNAL OF CHEMISTRY

Fmoc Synthesis of Peptide Thioesters without Post-Chain-Assembly Manipulation

(2011) Ji-Shen Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Big Defensins, a Diverse Family of Antimicrobial Peptides That Follows Different Patterns of Expression in Hemocytes of the Oyster Crassostrea gigas

(2011) Rafael D. Rosa et al.   PLoS One

Total Chemical Synthesis of Di-ubiquitin Chains

(2010) K. S. Ajish Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

9-Fluorenylmethoxycarbonyl-Based Solid-Phase Synthesis of Peptide α-Thioesters

(2010) Franziska Mende et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An investigation into the origin of the dramatically reduced reactivity of peptide-prolyl-thioesters in native chemical ligation

(2010) Samuel B. Pollock et al.   CHEMICAL COMMUNICATIONS

N-Methylcysteine-mediated total chemical synthesis of ubiquitin thioester

(2010) Lesly A. Erlich et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Bis(2-sulfanylethyl)amino Native Peptide Ligation

(2010) Nathalie Ollivier et al.   ORGANIC LETTERS

PeptidylN,N-Bis(2-mercaptoethyl)-amides as Thioester Precursors for Native Chemical Ligation†

(2010) Wen Hou et al.   ORGANIC LETTERS

N→SAcyl-Transfer-Mediated Synthesis of Peptide Thioesters Using Anilide Derivatives

(2009) Shugo Tsuda et al.   ORGANIC LETTERS

An Efficient Fmoc-SPPS Approach for the Generation of Thioester Peptide Precursors for Use in Native Chemical Ligation

(2008) Juan B. Blanco-Canosa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters

(2008) Jaskiranjit Kang et al.   CHEMICAL COMMUNICATIONS