Aryl Hydrocarbon Receptor and Kynurenine: Recent Advances in Autoimmune Disease Research

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR

(2015) Ulrike M. Litzenburger et al.   Oncotarget

The Aryl Hydrocarbon Receptor: Multitasking in the Immune System

(2014) Brigitta Stockinger et al.   Annual Review of Immunology

The Aryl Hydrocarbon Receptor Promotes IL-10 Production by NK Cells

(2014) S. Wagage et al.   JOURNAL OF IMMUNOLOGY

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

Kynurenines in CNS disease: regulation by inflammatory cytokines

(2014) Brian M. Campbell et al.   Frontiers in Neuroscience

The roles of aryl hydrocarbon receptor in immune responses

(2013) Nam Trung Nguyen et al.   INTERNATIONAL IMMUNOLOGY

MyD88 as a target of microRNA-203 in regulation of lipopolysaccharide or Bacille Calmette-Guerin induced inflammatory response of macrophage RAW264.7 cells

(2013) Jun Wei et al.   MOLECULAR IMMUNOLOGY

Differential Influences of the Aryl Hydrocarbon Receptor on Th17 Mediated Responses in vitro and in vivo

(2013) João H. Duarte et al.   PLoS One

Aryl hydrocarbon receptor-mediated induction of the microRNA-132/212 cluster promotes interleukin-17-producing T-helper cell differentiation

(2013) T. Nakahama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aryl hydrocarbon receptor and experimental autoimmune arthritis

(2013) Nam Trung Nguyen et al.   Seminars in Immunopathology

The ARNT–STAT3 axis regulates the differentiation of intestinal intraepithelial TCRαβ+CD8αα+ cells

(2013) Kohei Nakajima et al.   Nature Communications

AhR is negatively regulated by miR-203 in response to TCDD or BaP treatment

(2013) Daochuan Li et al.   Toxicology Research

Posttranslational modification of indoleamine 2,3-dioxygenase

(2012) Hidetsugu Fujigaki et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The Kynurenine Pathway in Brain Tumor Pathogenesis

(2012) S. Adams et al.   CANCER RESEARCH

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

(2012) L. Pilotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aryl hydrocarbon receptor controls regulatory CD4+T cell function

(2012) C Pot   SWISS MEDICAL WEEKLY

AHR and the Transcriptional Regulation of Type-17/22 ILC

(2012) Jacob S. Lee et al.   Frontiers in Immunology

Role of the Aryl Hydrocarbon Receptor in Controlling Maintenance and Functional Programs of RORγt+ Innate Lymphoid Cells and Intraepithelial Lymphocytes

(2012) Elina A. Kiss et al.   Frontiers in Immunology

AhR deficiency impairs expression of LPS-induced inflammatory genes in mice

(2011) Dalei Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

(2011) Ying Li et al.   CELL

A Role of the Aryl Hydrocarbon Receptor in Attenuation of Colitis

(2011) Keisuke Furumatsu et al.   DIGESTIVE DISEASES AND SCIENCES

Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract

(2011) Ivan Monteleone et al.   GASTROENTEROLOGY

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

(2011) Ju Qiu et al.   IMMUNITY

Aryl hydrocarbon receptor negatively regulates LPS-induced IL-6 production through suppression of histamine production in macrophages

(2011) Kazuya Masuda et al.   INTERNATIONAL IMMUNOLOGY

Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation

(2011) Guoliang Cui et al.   JOURNAL OF CLINICAL INVESTIGATION

Aryl Hydrocarbon Receptor Is Critical for Homeostasis of Invariant    T Cells in the Murine Epidermis

(2011) S. Kadow et al.   JOURNAL OF IMMUNOLOGY

Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients

(2011) Valentina Durastanti et al.   Journal of Translational Medicine

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

(2011) Jacob S Lee et al.   NATURE IMMUNOLOGY

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

In Vivo Induction of Tr1 Cells via Mucosal Dendritic Cells and AHR Signaling

(2011) Henry Yim Wu et al.   PLoS One

Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis

(2011) T. Nakahama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TCDD: An Environmental Immunotoxicant Reveals a Novel Pathway of Immunoregulation—A 30-Year Odyssey

(2011) Nancy I. Kerkvliet   TOXICOLOGIC PATHOLOGY

Regulation of Bach2 by the aryl hydrocarbon receptor as a mechanism for suppression of B-cell differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin

(2011) K. Nadira De Abrew et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Activation of the aryl hydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice

(2010) Takeyuki Takamura et al.   IMMUNOLOGY AND CELL BIOLOGY

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

IDO Upregulates Regulatory T Cells via Tryptophan Catabolite and Suppresses Encephalitogenic T Cell Responses in Experimental Autoimmune Encephalomyelitis

(2010) Y. Yan et al.   JOURNAL OF IMMUNOLOGY

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells

(2010) Roopali Gandhi et al.   NATURE IMMUNOLOGY

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kynurenic Acid Is a Potent Endogenous Aryl Hydrocarbon Receptor Ligand that Synergistically Induces Interleukin-6 in the Presence of Inflammatory Signaling

(2010) Brett C. DiNatale et al.   TOXICOLOGICAL SCIENCES

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

The aryl hydrocarbon receptor: a perspective on potential roles in the immune system

(2009) Emily A. Stevens et al.   IMMUNOLOGY

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

(2009) Akihiro Kimura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Langerhans Cell Maturation and Contact Hypersensitivity Are Impaired in Aryl Hydrocarbon Receptor-Null Mice

(2009) B. Jux et al.   JOURNAL OF IMMUNOLOGY

Hypersensitivity of Aryl Hydrocarbon Receptor-Deficient Mice to Lipopolysaccharide-Induced Septic Shock

(2009) H. Sekine et al.   MOLECULAR AND CELLULAR BIOLOGY

The Aryl Hydrocarbon Receptor Activator Benzo[a]pyrene Enhances Vitamin D3 Catabolism in Macrophages

(2009) Manabu Matsunawa et al.   TOXICOLOGICAL SCIENCES

The aryl hydrocarbon receptor in immunity

(2009) Charlotte Esser et al.   TRENDS IN IMMUNOLOGY

Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

(2009) Masaaki Kanai et al.   Molecular Brain

Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase

(2008) Christoph F.A. Vogel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: A role for IFN-γ?

(2008) Thomas J. Connor et al.   NEUROSCIENCE LETTERS

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

(2008) A. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis

(2008) C. Orabona et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Search for Endogenous Activators of the Aryl Hydrocarbon Receptor

(2007) Linh P. Nguyen et al.   CHEMICAL RESEARCH IN TOXICOLOGY