Distilling complexity to advance cardiac tissue engineering

Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes

(2016) George Eng et al.   Nature Communications

Inhibition of  -catenin signaling respecifies anterior-like endothelium into beating human cardiomyocytes

(2015) N. J. Palpant et al.   DEVELOPMENT

Human embryonic stem cell-derived cardiac progenitors for severe heart failure treatment: first clinical case report: Figure 1

(2015) Philippe Menasché et al.   EUROPEAN HEART JOURNAL

A prospective comparison of alginate-hydrogel with standard medical therapy to determine impact on functional capacity and clinical outcomes in patients with advanced heart failure (AUGMENT-HF trial)

(2015) Stefan D. Anker et al.   EUROPEAN HEART JOURNAL

Hurdles to clinical translation of human induced pluripotent stem cells

(2015) Evgenios Neofytou et al.   JOURNAL OF CLINICAL INVESTIGATION

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

(2015) Alexandre J. S. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

(2015) J. T. Hinson et al.   SCIENCE

An integrated statistical model for enhanced murine cardiomyocyte differentiation via optimized engagement of 3D extracellular matrices

(2015) Jangwook P. Jung et al.   Scientific Reports

Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts

(2015) Kaytlyn A. Gerbin et al.   PLoS One

Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications

(2015) Anurag Mathur et al.   Scientific Reports

Heart Regeneration with Engineered Myocardial Tissue

(2014) Kareen L.K. Coulombe et al.   Annual Review of Biomedical Engineering

Patching Up Broken Hearts: Cardiac Cell Therapy Gets a Bioengineered Boost

(2014) Vahid Serpooshan et al.   Cell Stem Cell

Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells

(2014) Lei Ye et al.   Cell Stem Cell

Ultrathin strut biodegradable polymer sirolimus-eluting stent versus durable polymer everolimus-eluting stent for percutaneous coronary revascularisation (BIOSCIENCE): a randomised, single-blind, non-inferiority trial

(2014) Thomas Pilgrim et al.   LANCET

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

(2014) James J. H. Chong et al.   NATURE

Generation of the epicardial lineage from human pluripotent stem cells

(2014) Alec D Witty et al.   NATURE BIOTECHNOLOGY

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

(2014) Gang Wang et al.   NATURE MEDICINE

Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes

(2013) Donghui Zhang et al.   BIOMATERIALS

Bioengineering heart tissue for in vitro testing

(2013) Elisa Cimetta et al.   CURRENT OPINION IN BIOTECHNOLOGY

Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes

(2013) Sara S Nunes et al.   NATURE METHODS

Feasibility, Safety, and Therapeutic Efficacy of Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Sheets in a Porcine Ischemic Cardiomyopathy Model

(2012) M. Kawamura et al.   CIRCULATION

Bioenergetic and Functional Consequences of Cellular Therapy

(2012) Qiang Xiong et al.   CIRCULATION RESEARCH

Microengineered physiological biomimicry: Organs-on-Chips

(2012) Dongeun Huh et al.   LAB ON A CHIP

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

(2012) Yuji Shiba et al.   NATURE

Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy

(2012) N. Sun et al.   Science Translational Medicine

Pluripotent Stem Cell-Engineered Cell Sheets Reassembled with Defined Cardiovascular Populations Ameliorate Reduction in Infarct Heart Function Through Cardiomyocyte-Mediated Neovascularization

(2012) Hidetoshi Masumoto et al.   STEM CELLS

Endothelium-Derived Neuregulin Protects the Heart Against Ischemic Injury

(2011) Nadia Hedhli et al.   CIRCULATION

Growth of Engineered Human Myocardium With Mechanical Loading and Vascular Coculture

(2011) Nathaniel L. Tulloch et al.   CIRCULATION RESEARCH

The road to biological pacing

(2011) Michael R. Rosen et al.   Nature Reviews Cardiology

Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies

(2011) Robert D. Kirkton et al.   Nature Communications

Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue

(2009) K. R. Stevens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA