The road to biological pacing

The dark side of induced pluripotency

(2011) Martin F. Pera   NATURE

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

(2011) Jem A. Efe et al.   NATURE CELL BIOLOGY

Induced Pluripotent Stem Cells — A Cautionary Note

(2011) Christine Mummery   NEW ENGLAND JOURNAL OF MEDICINE

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Enhanced Reprogramming and Cardiac Differentiation of Human Keratinocytes Derived from Plucked Hair Follicles, Using a Single Excisable Lentivirus

(2010) Atara Novak et al.   Cellular Reprogramming

A Coupled SYSTEM of Intracellular Ca 2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heart’s Pacemaker

(2010) Edward G. Lakatta et al.   CIRCULATION RESEARCH

Biological pacemakers in canines exhibit positive chronotropic response to emotional arousal

(2010) Iryna N. Shlapakova et al.   HEART RHYTHM

Cardiac expression of skeletal muscle sodium channels increases longitudinal conduction velocity in the canine 1-week myocardial infarction

(2010) Ruben Coronel et al.   HEART RHYTHM

Fibrin microthreads support mesenchymal stem cell growth while maintaining differentiation potential

(2010) Megan K. Proulx et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Adenylate-Cyclase VI Transforms Ventricular Cardiomyocytes into Biological Pacemaker Cells

(2010) Arjang Ruhparwar et al.   TISSUE ENGINEERING PART A

Intracellular Calcium Dynamics and Acceleration of Sinus Rhythm by β-Adrenergic Stimulation

(2009) Boyoung Joung et al.   CIRCULATION

Molecular Architecture of the Human Sinus Node

(2009) Natalie J. Chandler et al.   CIRCULATION

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2009) Jianhua Zhang et al.   CIRCULATION RESEARCH

Biological pacemakers as a therapy for cardiac arrhythmias

(2009) Eduardo Marbán et al.   CURRENT OPINION IN CARDIOLOGY

What keeps us ticking: a funny current, a calcium clock, or both?

(2009) Edward G. Lakatta et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac connexins and impulse propagation

(2009) John A. Jansen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Coupling an HCN2-expressing cell to a myocyte creates a two-cell pacing unit

(2009) V. Valiunas et al.   JOURNAL OF PHYSIOLOGY-LONDON

Expression of skeletal but not cardiac Na+ channel isoform preserves normal conduction in a depolarized cardiac syncytium

(2008) Lev Protas et al.   CARDIOVASCULAR RESEARCH

Epicardial Border Zone Overexpression of Skeletal Muscle Sodium Channel SkM1 Normalizes Activation, Preserves Conduction, and Suppresses Ventricular Arrhythmia

(2008) David H. Lau et al.   CIRCULATION

Cardiac Pacing

(2008) Michael R. Rosen et al.   Circulation-Arrhythmia and Electrophysiology

Ca2+-stimulated Basal Adenylyl Cyclase Activity Localization in Membrane Lipid Microdomains of Cardiac Sinoatrial Nodal Pacemaker Cells

(2008) Antoine Younes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HCN212-channel biological pacemakers manifesting ventricular tachyarrhythmias are responsive to treatment with If blockade

(2007) Alexei N. Plotnikov et al.   HEART RHYTHM