Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3–induced outside-in signaling and clusterin release

Antibody against Small Aggregated Peptide Specifically Recognizes Toxic Aβ-42 Oligomers in Alzheimer’s Disease

(2015) Riddhi U. Bodani et al.   ACS Chemical Neuroscience

Increased CSF A  during the very early phase of cerebral A  deposition in mouse models

(2015) L. F. Maia et al.   EMBO Molecular Medicine

Loss of oligophrenin1 leads to uncontrolled Rho activation and increased thrombus formation in mice

(2015) A. Fotinos et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

2014 Alzheimer's disease facts and figures

(2014)   Alzheimers & Dementia

Amyloid β-peptide-dependent activation of human platelets: essential role for Ca2+and ADP in aggregation and thrombus formation

(2014) Ilaria Canobbio et al.   BIOCHEMICAL JOURNAL

Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer's disease

(2014) Andrea Jarre et al.   CELLULAR SIGNALLING

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Blood Platelets in the Progression of Alzheimer’s Disease

(2014) Nina S. Gowert et al.   PLoS One

Platelets, a reliable source for peripheral Alzheimer’s disease biomarkers?

(2014) Michael Veitinger et al.   Acta Neuropathologica Communications

The worldwide economic impact of dementia 2010

(2013) Anders Wimo et al.   Alzheimers & Dementia

Acid Sphingomyelinase Regulates Platelet Cell Membrane Scrambling, Secretion, and Thrombus Formation

(2013) Patrick Münzer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice

(2013) Götz Heilbronner et al.   EMBO REPORTS

Immobilized amyloid Aβ peptides support platelet adhesion and activation

(2013) Ilaria Canobbio et al.   FEBS LETTERS

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Membrane-Anchored A  Accelerates Amyloid Formation and Exacerbates Amyloid-Associated Toxicity in Mice

(2013) A. Nagarathinam et al.   JOURNAL OF NEUROSCIENCE

Clusterin in Alzheimer’s disease: a player in the biological behavior of amyloid-beta

(2013) Xiang Li et al.   Neuroscience Bulletin

α5β1-integrins are sensors for tauroursodeoxycholic acid in hepatocytes

(2012) Holger Gohlke et al.   HEPATOLOGY

Alzheimer disease and platelets: how’s that relevant

(2012) Silvia Catricala et al.   Immunity & Ageing

Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models

(2011) A. T. Nurden et al.   BLOOD

Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease

(2010) Madhav Thambisetty et al.   ARCHIVES OF GENERAL PSYCHIATRY

Activation of Integrins by Urea in Perfused Rat Liver

(2010) Roland Reinehr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Capture of endothelial progenitor cells by a bispecific protein/monoclonal antibody molecule induces reendothelialization of vascular lesions

(2010) Harald F. Langer et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives

(2010) Harald Hampel et al.   NATURE REVIEWS DRUG DISCOVERY

Fibrinogen and β-Amyloid Association Alters Thrombosis and Fibrinolysis: A Possible Contributing Factor to Alzheimer's Disease

(2010) Marta Cortes-Canteli et al.   NEURON

Alzheimer's disease peptide  -amyloid interacts with fibrinogen and induces its oligomerization

(2010) H. J. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripherally Applied A -Containing Inoculates Induce Cerebral  -Amyloidosis

(2010) Y. S. Eisele et al.   SCIENCE

Novel Mutations in the GPIIb and GPIIIa Genes in Glanzmann Thrombasthenia

(2010) Daniele Pillitteri et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

Clusterin: A forgotten player in Alzheimer's disease

(2009) Tapio Nuutinen et al.   BRAIN RESEARCH REVIEWS

Cerebral perfusion (HMPAO-SPECT) in patients with depression with cognitive impairment versus those with mild cognitive impairment and dementia of Alzheimer’s type: a semiquantitative and automated evaluation

(2009) W. Staffen et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Integrin Activation Dynamics between the RGD-binding Site and the Headpiece Hinge

(2009) Eileen Puklin-Faucher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrins in platelet activation

(2009) B. NIESWANDT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Clopidogrel attenuates atheroma formation and induces a stable plaque phenotype in apolipoprotein E knockout mice

(2009) Arnon Afek et al.   MICROVASCULAR RESEARCH

Inhibition of platelet aggregation by 1-methyl-4-phenyl pyridinium ion (MPP+) through ATP depletion: Evidence for the reduced platelet activities in Parkinson's disease

(2009) Kyung-Min Lim et al.   PLATELETS

Comparison of Alzheimer A (1-40) and A (1-42) amyloid fibrils reveals similar protofilament structures

(2009) M. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Amyloid, Blood Vessels, and Brain Function

(2009) Eric E. Smith et al.   STROKE

Cerebral amyloid angiopathy and its relationship to Alzheimer’s disease

(2008) Dietmar Rudolf Thal et al.   ACTA NEUROPATHOLOGICA

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

(2008) Alex E. Roher et al.   Alzheimers & Dementia

Amyloid beta peptide-activated signal pathways in human platelets

(2008) Ming Y. Shen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Structural basis for distinctive recognition of fibrinogen γC peptide by the platelet integrin αIIbβ3

(2008) Timothy A. Springer et al.   JOURNAL OF CELL BIOLOGY

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

(2008) Jianghai Zhu et al.   MOLECULAR CELL

Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances

(2008) Dietmar Rudolf Thal et al.   NEUROBIOLOGY OF AGING