Loss of oligophrenin1 leads to uncontrolled Rho activation and increased thrombus formation in mice
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Title
Loss of oligophrenin1 leads to uncontrolled Rho activation and increased thrombus formation in mice
Authors
Keywords
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Journal
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
Volume 13, Issue 4, Pages 619-630
Publisher
Wiley
Online
2014-12-31
DOI
10.1111/jth.12834
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Note: Only part of the references are listed.- Targeted Phosphotyrosine Profiling of Glycoprotein VI Signaling Implicates Oligophrenin-1 in Platelet Filopodia Formation
- (2013) Onno B. Bleijerveld et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Rho GTPase signaling at the synapse: Implications for intellectual disability
- (2013) Wei Ba et al. EXPERIMENTAL CELL RESEARCH
- Intracellular cyclophilin A is an important Ca2+ regulator in platelets and critically involved in arterial thrombus formation
- (2012) M. Elvers et al. BLOOD
- The GRAF family member oligophrenin1 is a RhoGAP with BAR domain and regulates Rho GTPases in platelets
- (2012) Margitta Elvers et al. CARDIOVASCULAR RESEARCH
- Isoform-specific roles of the GTPase activating protein Nadrin in cytoskeletal reorganization of platelets
- (2012) S. Beck et al. CELLULAR SIGNALLING
- The Inflammatory Chemokine CXC Motif Ligand 16 Triggers Platelet Activation and Adhesion Via CXC Motif Receptor 6–Dependent Phosphatidylinositide 3-Kinase/Akt Signaling
- (2012) Oliver Borst et al. CIRCULATION RESEARCH
- Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis
- (2011) I. Pleines et al. BLOOD
- The serum- and glucocorticoid-inducible kinase 1 (SGK1) influences platelet calcium signaling and function by regulation of Orai1 expression in megakaryocytes
- (2011) O. Borst et al. BLOOD
- Signaling During Platelet Adhesion and Activation
- (2010) Zhenyu Li et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets
- (2010) I. Pleines et al. BLOOD
- Impaired IIb 3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1
- (2010) M. Elvers et al. Science Signaling
- Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation
- (2009) Malik Khelfaoui et al. HUMAN MOLECULAR GENETICS
- Integrins in platelet activation
- (2009) B. NIESWANDT et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Mammalian Rho GTPases: new insights into their functions from in vivo studies
- (2008) Sarah J. Heasman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Rac1 is essential for phospholipase C-γ2 activation in platelets
- (2008) Irina Pleines et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
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