Amyloid β-peptide-dependent activation of human platelets: essential role for Ca2+and ADP in aggregation and thrombus formation

Amyloid β peptide stimulates platelet activation through RhoA-dependent modulation of actomyosin organization

(2014) Vijay K. Sonkar et al.   FASEB JOURNAL

Blood Platelets in the Progression of Alzheimer’s Disease

(2014) Nina S. Gowert et al.   PLoS One

Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca2+-dependent activation of platelet Rap1b GTPase

(2013) Gianni Francesco Guidetti et al.   BIOCHEMICAL JOURNAL

Amyloid precursor protein expression is enhanced in human platelets from subjects with Alzheimer's disease and frontotemporal lobar degeneration: A Real-time PCR study

(2013) Arianna Vignini et al.   EXPERIMENTAL GERONTOLOGY

Immobilized amyloid Aβ peptides support platelet adhesion and activation

(2013) Ilaria Canobbio et al.   FEBS LETTERS

Autocrine amplification of integrin αIIbβ3 activation and platelet adhesive responses by deoxyribose-1-phosphate

(2013) Dina S. Vara et al.   THROMBOSIS AND HAEMOSTASIS

Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca2+-dependent tyrosine kinase Pyk2

(2012) I. Canobbio et al.   BLOOD

The novel NOX inhibitor 2-acetylphenothiazine impairs collagen-dependent thrombus formation in a GPVI-dependent manner

(2012) D Vara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reduced platelet amyloid precursor protein ratio (APP ratio) predicts conversion from mild cognitive impairment to Alzheimer’s disease

(2012) Isis A. Zainaghi et al.   JOURNAL OF NEURAL TRANSMISSION

Alzheimer disease and platelets: how’s that relevant

(2012) Silvia Catricala et al.   Immunity & Ageing

Cerebral amyloid angiopathy in the elderly

(2011) Anand Viswanathan et al.   ANNALS OF NEUROLOGY

Calmodulin regulates the non-amyloidogenic metabolism of amyloid precursor protein in platelets

(2010) I. Canobbio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Conformations and Biological Activities of Amyloid Beta Peptide 25-35

(2010) L. Millucci et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Calcium Signaling and Amyloid Toxicity in Alzheimer Disease

(2010) Angelo Demuro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential phosphorylation of myosin light chain (Thr)18 and (Ser)19 and functional implications in platelets

(2010) T. M. GETZ et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Epinephrine-mediated protein kinase C and Rap1b activation requires the co-stimulation of Gz-, Gq-, and Gi-coupled receptors

(2010) Ilaria Canobbio et al.   THROMBOSIS AND HAEMOSTASIS

A Specific Enzyme-Linked Immunosorbent Assay for Measuring β-Amyloid Protein Oligomers in Human Plasma and Brain Tissue of Patients With Alzheimer Disease

(2009) Weiming Xia et al.   ARCHIVES OF NEUROLOGY

Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis

(2009) L. Lian et al.   BLOOD

Subcellular and metabolic examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence for Aβ25–35

(2009) Yury G. Kaminsky et al.   EXPERIMENTAL NEUROLOGY

A PP/APLP2 Family of Kunitz Serine Proteinase Inhibitors Regulate Cerebral Thrombosis

(2009) F. Xu et al.   JOURNAL OF NEUROSCIENCE

Amyloid beta peptide-activated signal pathways in human platelets

(2008) Ming Y. Shen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Expression of amyloid beta peptide in human platelets: Pivotal role of the phospholipase Cγ2-protein kinase C pathway in platelet activation

(2008) Ming-Yi Shen et al.   PHARMACOLOGICAL RESEARCH