Acid Sphingomyelinase Regulates Platelet Cell Membrane Scrambling, Secretion, and Thrombus Formation

Regulation of STIM1/Orai1-dependent Ca2+ signalling in platelets

(2013) Patrick Münzer et al.   THROMBOSIS AND HAEMOSTASIS

The Inflammatory Chemokine CXC Motif Ligand 16 Triggers Platelet Activation and Adhesion Via CXC Motif Receptor 6–Dependent Phosphatidylinositide 3-Kinase/Akt Signaling

(2012) Oliver Borst et al.   CIRCULATION RESEARCH

Lipid Raft Redox Signaling: Molecular Mechanisms in Health and Disease

(2011) Si Jin et al.   ANTIOXIDANTS & REDOX SIGNALING

The serum- and glucocorticoid-inducible kinase 1 (SGK1) influences platelet calcium signaling and function by regulation of Orai1 expression in megakaryocytes

(2011) O. Borst et al.   BLOOD

Ceramide formation as a target in beta-cell survival and function

(2011) Florian Lang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Identification of Novel Functional Inhibitors of Acid Sphingomyelinase

(2011) Johannes Kornhuber et al.   PLoS One

Platelets

(2010) Shashank Jain et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelets

(2010) Cara C. Bertozzi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet–Leukocyte Interactions in Cardiovascular Disease and Beyond

(2010) Licia Totani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ceramide in Pseudomonas aeruginosa Infections and Cystic Fibrosis

(2010) Katrin Anne Becker et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Spingolipids in Multiple Sclerosis

(2010) Silke Walter et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): A Novel Pharmacological Group of Drugs with Broad Clinical Applications

(2010) Johannes Kornhuber et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Vascular Barrier Regulation by PAF, Ceramide, Caveolae, and NO - an Intricate Signaling Network with Discrepant Effects in the Pulmonary and Systemic Vasculature

(2010) Wolfgang M. Kuebler et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ceramide in Suicidal Death of Erythrocytes

(2010) Florian Lang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Ceramide-rich platforms in transmembrane signaling

(2010) Branka Stancevic et al.   FEBS LETTERS

Sphingomyelinase dependent apoptosis of dendritic cells following treatment with amyloid peptides

(2010) Nguyen Thi Xuan et al.   JOURNAL OF NEUROIMMUNOLOGY

Lipids control mucus production in cystic fibrosis

(2010) Erich Gulbins   NATURE MEDICINE

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function

(2009) S. M. Schoenwaelder et al.   BLOOD

Acid sphingomyelinase activity triggers microparticle release from glial cells

(2009) Fabio Bianco et al.   EMBO JOURNAL

Acid sphingomyelinase, cell membranes and human disease: Lessons from Niemann-Pick disease

(2009) Edward H. Schuchman   FEBS LETTERS

Calcium signaling in platelets

(2009) D. VARGA-SZABO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes

(2009) Jasmin Herz et al.   NATURE IMMUNOLOGY

Acid Sphingomyelinase Promotes Lipoprotein Retention Within Early Atheromata and Accelerates Lesion Progression

(2008) Cecilia M. Devlin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights fromin VivoManipulation of Sphingolipid Metabolism

(2008) William L. Holland et al.   ENDOCRINE REVIEWS

The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases

(2008) Eric L. Smith et al.   FASEB JOURNAL

Protection from High Fat Diet-induced Increase in Ceramide in Mice Lacking Plasminogen Activator Inhibitor 1

(2008) Charmi Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

(2008) Volker Teichgräber et al.   NATURE MEDICINE

Aggravation of viral hepatitis by platelet-derived serotonin

(2008) Philipp A Lang et al.   NATURE MEDICINE

Lipid signalling in disease

(2008) Matthias P. Wymann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Critical Role of Lipid Raft Redox Signaling Platforms in Endostatin-Induced Coronary Endothelial Dysfunction

(2007) Si Jin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY