Translational tuning optimizes nascent protein folding in cells

Comparing protein folding in vitro and in vivo: foldability meets the fitness challenge

(2014) Karan S Hingorani et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Expanding Anfinsen’s Principle: Contributions of Synonymous Codon Selection to Rational Protein Design

(2014) Ian M. Sander et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Cotranslational Function of Ribosome-Associated Hsp70 in Eukaryotic Protein Homeostasis

(2013) Felix Willmund et al.   CELL

Co-translational mechanisms of protein maturation

(2013) Felix Gloge et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Reshaping of the conformational search of a protein by the chaperone trigger factor

(2013) Alireza Mashaghi et al.   NATURE

Non-optimal codon usage affects expression, structure and function of clock protein FRQ

(2013) Mian Zhou et al.   NATURE

Folding the proteome

(2013) Esther Braselmann et al.   TRENDS IN BIOCHEMICAL SCIENCES

Large-scale analysis of conserved rare codon clusters suggests an involvement in co-translational molecular recognition events

(2012) Matthieu Chartier et al.   BIOINFORMATICS

Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences

(2012) Juan L. Mendoza et al.   CELL

Silent Substitutions Predictably Alter Translation Elongation Rates and Protein Folding Efficiencies

(2012) Paige S. Spencer et al.   JOURNAL OF MOLECULAR BIOLOGY

Allosteric Modulation Balances Thermodynamic Stability and Restores Function of ΔF508 CFTR

(2012) Andrei A. Aleksandrov et al.   JOURNAL OF MOLECULAR BIOLOGY

Stepwise Insertion and Inversion of a Type II Signal Anchor Sequence in the Ribosome-Sec61 Translocon Complex

(2011) Prasanna K. Devaraneni et al.   CELL

Kinetic Analysis of Ribosome-bound Fluorescent Proteins Reveals an Early, Stable, Cotranslational Folding Intermediate

(2011) Devaki A. Kelkar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Scenarios of Protein Folding Can Occur on the Ribosome

(2011) Edward P. O’Brien et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum–associated degradation

(2011) Yoshihiro Matsumura et al.   MOLECULAR BIOLOGY OF THE CELL

Ligand-Driven Vectorial Folding of Ribosome-Bound Human CFTR NBD1

(2011) Amardeep Khushoo et al.   MOLECULAR CELL

The Ribosome Modulates Nascent Protein Folding

(2011) C. M. Kaiser et al.   SCIENCE

Cotranslational Folding Increases GFP Folding Yield

(2010) Krastyu G. Ugrinov et al.   BIOPHYSICAL JOURNAL

Cotranslational structure acquisition of nascent polypeptides monitored by NMR spectroscopy

(2010) C. Eichmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis

(2010) Chi Wang et al.   PROTEIN SCIENCE

In vitro incorporation of nonnatural amino acids into protein using tRNACys-derived opal, ochre, and amber suppressor tRNAs

(2010) J. Gubbens et al.   RNA

Diffusion, Crowding & Protein Stability in a Dynamic Molecular Model of the Bacterial Cytoplasm

(2010) Sean R. McGuffee et al.   PLoS Computational Biology

Structure and Dynamics of NBD1 from CFTR Characterized Using Crystallography and Hydrogen/Deuterium Exchange Mass Spectrometry

(2009) H.A. Lewis et al.   JOURNAL OF MOLECULAR BIOLOGY

Tertiary interactions within the ribosomal exit tunnel

(2009) Andrey Kosolapov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transient ribosomal attenuation coordinates protein synthesis and co-translational folding

(2009) Gong Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Probing ribosome-nascent chain complexes produced in vivo by NMR spectroscopy

(2009) Lisa D. Cabrita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GtRNAdb: a database of transfer RNA genes detected in genomic sequence

(2008) P. P. Chan et al.   NUCLEIC ACIDS RESEARCH