Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Computationally efficient molecular dynamics integrators with improved sampling accuracy

(2012) Cristian Predescu et al.   MOLECULAR PHYSICS

B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study

(2012) Barton F Haynes et al.   NATURE BIOTECHNOLOGY

A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center

(2011) Tanja A. Schwickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epitope-Specific Human Influenza Antibody Repertoires Diversify by B Cell Intraclonal Sequence Divergence and Interclonal Convergence

(2011) J. C. Krause et al.   JOURNAL OF IMMUNOLOGY

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

(2011) J. R. R. Whittle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

(2011) J. F. Scheid et al.   SCIENCE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

OpenStructure: a flexible software framework for computational structural biology

(2010) Marco Biasini et al.   BIOINFORMATICS

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies

(2009) Hua-Xin Liao et al.   JOURNAL OF VIROLOGICAL METHODS

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

(2008) Jens Wrammert et al.   NATURE

Multi-constraint computational design suggests that native sequences of germline antibody H3 loops are nearly optimal for conformational flexibility

(2008) Mariana Babor et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS