Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis

Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases

(2016) Wei-Hung Chen et al.   ACS Chemical Biology

Structures of two distinct conformations of holo-non-ribosomal peptide synthetases

(2016) Eric J. Drake et al.   NATURE

Structural elements of an NRPS cyclization domain and its intermodule docking domain

(2016) Daniel P. Dowling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis

(2015) Nicole M. Gaudelli et al.   NATURE

The structural biology of biosynthetic megaenzymes

(2015) Kira J Weissman   Nature Chemical Biology

The colibactin warhead crosslinks DNA

(2015) Maria I. Vizcaino et al.   Nature Chemistry

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

(2015) Tilmann Weber et al.   NUCLEIC ACIDS RESEARCH

Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes

(2014) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the epimerization domain of tyrocidine synthetase A

(2014) Stefan A. Samel et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases

(2013) Kristjan Bloudoff et al.   JOURNAL OF MOLECULAR BIOLOGY

The role of aromatic L-amino acid decarboxylase in bacillamide C biosynthesis by Bacillus atrophaeus C89

(2013) Lei Yuwen et al.   Scientific Reports

Analyses of MbtB, MbtE, and MbtF Suggest Revisions to the Mycobactin Biosynthesis Pathway in Mycobacterium tuberculosis

(2012) M. D. McMahon et al.   JOURNAL OF BACTERIOLOGY

Mixing and Matching Siderophore Clusters: Structure and Biosynthesis of Serratiochelins from Serratia sp. V4

(2012) Mohammad R. Seyedsayamdost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations

(2012) Kyle L Dunbar et al.   Nature Chemical Biology

The Natural Product Domain Seeker NaPDoS: A Phylogeny Based Bioinformatic Tool to Classify Secondary Metabolite Gene Diversity

(2012) Nadine Ziemert et al.   PLoS One

Evolution of lanthipeptide synthetases

(2012) Q. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence context-specific profiles for homology searching

(2009) A. Biegert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tandem heterocyclization domains in a nonribosomal peptide synthetase essential for siderophore biosynthesis in Vibrio anguillarum

(2008) Manuela Di Lorenzo et al.   BIOMETALS

Effects of bacillamide and newly synthesized derivatives on the growth of cyanobacteria and microalgae cultures

(2008) C. Churro et al.   JOURNAL OF APPLIED PHYCOLOGY

Unconventional serine proteases: Variations on the catalytic Ser/His/Asp triad configuration

(2008) Özlem Doğan Ekici et al.   PROTEIN SCIENCE