Prions, amyloids, and RNA: Pieces of a puzzle

A structure-based approach to predict predisposition to amyloidosis

(2015) Abdullah B. Ahmed et al.   Alzheimers & Dementia

Amyloids: from pathogenesis to function

(2015) A. A. Nizhnikov et al.   BIOCHEMISTRY-MOSCOW

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3

(2015) Luana Fioriti et al.   NEURON

Amyloid-like assembly of the low complexity domain of yeast Nab3

(2015) Thomas W O'Rourke et al.   Prion

From nucleation to widespread propagation: A prion-like concept for ALS

(2015) Zuzanna Maniecka et al.   VIRUS RESEARCH

SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3

(2015) Bettina Drisaldi et al.   Cell Reports

The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton

(2015) Joseph S. Stephan et al.   Cell Reports

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

(2015) Sonja Kroschwald et al.   eLife

Nomenclature 2014: Amyloid fibril proteins and clinical classification of the amyloidosis

(2014) Jean D. Sipe et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Biofilms formed by the archaeon Haloferax volcaniiexhibit cellular differentiation and social motility, and facilitate horizontal gene transfer

(2014) Scott Chimileski et al.   BMC BIOLOGY

Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism

(2014) Daniel F. Jarosz et al.   CELL

Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation

(2014) Xin Cai et al.   CELL

Amyloid diseases of yeast: prions are proteins acting as genes

(2014) Reed B. Wickner et al.   Essays in Biochemistry

Transcriptional response to the [ISP+] prion ofSaccharomyces cerevisiaediffers from that induced by the deletion of its structural gene,SFP1

(2014) Polina Drozdova et al.   FEMS YEAST RESEARCH

Prion-like determinant [NSI +] decreases the expression of the SUP45 gene in Saccharomyces cerevisiae

(2014) A. M. Kondrashkina et al.   MOLECULAR BIOLOGY

Functional Role of Tia1/Pub1 and Sup35 Prion Domains: Directing Protein Synthesis Machinery to the Tubulin Cytoskeleton

(2014) Xiang Li et al.   MOLECULAR CELL

Transcription, Epigenetics and Ameliorative Strategies in Huntington’s Disease: a Genome-Wide Perspective

(2014) Luis M. Valor   MOLECULAR NEUROBIOLOGY

Sequence Complexity of Amyloidogenic Regions in Intrinsically Disordered Human Proteins

(2014) Swagata Das et al.   PLoS One

Interaction Networks of Prion, Prionogenic and Prion-Like Proteins in Budding Yeast, and Their Role in Gene Regulation

(2014) Djamel Harbi et al.   PLoS One

Proteomic Screening for Amyloid Proteins

(2014) Anton A. Nizhnikov et al.   PLoS One

Modulation of efficiency of translation termination inSaccharomyces cerevisiae

(2014) Anton A Nizhnikov et al.   Prion

mRNP granules

(2014) J Ross Buchan   RNA Biology

RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis

(2014) Ho Yin Edwin Chan   Frontiers in Cellular Neuroscience

Amyloid-associated activity contributes to the severity and toxicity of a prion phenotype

(2014) John A. Pezza et al.   Nature Communications

Contribution of Orb2A Stability in Regulated Amyloid-Like Oligomerization of Drosophila Orb2

(2014) Erica White-Grindley et al.   PLOS BIOLOGY

Extensive Diversity of Prion Strains Is Defined by Differential Chaperone Interactions and Distinct Amyloidogenic Regions

(2014) Kevin C. Stein et al.   PLoS Genetics

Fold modulating function: bacterial toxins to functional amyloids

(2014) Adnan K. Syed et al.   Frontiers in Microbiology

Molecular Structures of Amyloid and Prion Fibrils: Consensus versus Controversy

(2013) Robert Tycko et al.   ACCOUNTS OF CHEMICAL RESEARCH

Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor

(2013) Jerson L. Silva et al.   BIOSCIENCE REPORTS

Heritable Remodeling of Yeast Multicellularity by an Environmentally Responsive Prion

(2013) Daniel L. Holmes et al.   CELL

Non-targeted Identification of Prions and Amyloid-forming Proteins from Yeast and Mammalian Cells

(2013) Dmitry Kryndushkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Interactions of [NSI +] prion-like determinant with SUP35 and VTS1 genes in Saccharomyces cerevisiae

(2013) A. A. Nizhnikov et al.   RUSSIAN JOURNAL OF GENETICS

Blessings in disguise: biological benefits of prion-like mechanisms

(2013) Gregory A. Newby et al.   TRENDS IN CELL BIOLOGY

The [PSI+] Prion Exists as a Dynamic Cloud of Variants

(2013) David A. Bateman et al.   PLoS Genetics

TDP-43 skeins show properties of amyloid in a subset of ALS cases

(2012) John L. Robinson et al.   ACTA NEUROPATHOLOGICA

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

(2012) Oliver D. King et al.   BRAIN RESEARCH

Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory

(2012) Amitabha Majumdar et al.   CELL

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

(2012) Tina W. Han et al.   CELL

[NSI +] determinant has a pleiotropic phenotypic manifestation that is modulated by SUP35, SUP45, and VTS1 genes

(2012) Anton A. Nizhnikov et al.   CURRENT GENETICS

Breaking the amyloidogenicity code: Methods to predict amyloids from amino acid sequence

(2012) Abdullah B. Ahmed et al.   FEBS LETTERS

Prions in Yeast

(2012) S. W. Liebman et al.   GENETICS

Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils

(2012) Ana P. D. Ano Bom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Molecular History of the Amyloidoses

(2012) Joel N. Buxbaum et al.   JOURNAL OF MOLECULAR BIOLOGY

Prions are a common mechanism for phenotypic inheritance in wild yeasts

(2012) Randal Halfmann et al.   NATURE

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Prion formation by a yeast GLFG nucleoporin

(2012) Randal Halfmann et al.   Prion

A Yeast Prion, Mod5, Promotes Acquired Drug Resistance and Cell Survival Under Environmental Stress

(2012) G. Suzuki et al.   SCIENCE

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB

(2012) Eric R Kandel   Molecular Brain

Polyglutamine tracts as modulators of transcriptional activation from yeast to mammals

(2011) Lilit Atanesyan et al.   BIOLOGICAL CHEMISTRY

A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies

(2011) T. Lashley et al.   BRAIN

The Core of Ure2p Prion Fibrils Is Formed by the N-Terminal Segment in a Parallel Cross-β Structure: Evidence from Solid-State NMR

(2011) Dmitry S. Kryndushkin et al.   JOURNAL OF MOLECULAR BIOLOGY

Implications of the prion-related Q/N domains in TDP-43 and FUS

(2011) Maria Udan et al.   Prion

Suicidal [PSI+] is a lethal yeast prion

(2011) R. P. McGlinchey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein-only mechanism induces self-perpetuating changes in the activity of neuronal Aplysia cytoplasmic polyadenylation element binding protein (CPEB)

(2011) S. U. Heinrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-complexity regions within protein sequences have position-dependent roles

(2010) Alain Coletta et al.   BMC Systems Biology

Aplysia CPEB Can Form Prion-like Multimers in Sensory Neurons that Contribute to Long-Term Facilitation

(2010) Kausik Si et al.   CELL

[NSI +]: a novel non-Mendelian nonsense suppressor determinant in Saccharomyces cerevisiae

(2010) Alsu F. Saifitdinova et al.   CURRENT GENETICS

Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors

(2010) Claudia B. Levy et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Stress-specific composition, assembly and kinetics of stress granules in Saccharomyces cerevisiae

(2010) J. R. Buchan et al.   JOURNAL OF CELL SCIENCE

Distinct Subregions of Swi1 Manifest Striking Differences in Prion Transmission and SWI/SNF Function

(2010) Z. Du et al.   MOLECULAR AND CELLULAR BIOLOGY

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

(2010) Sebastian Maurer-Stroh et al.   NATURE METHODS

The prion hypothesis: from biological anomaly to basic regulatory mechanism

(2010) Mick F. Tuite et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue

(2010) Liqun Liu-Yesucevitz et al.   PLoS One

Interdependence of amyloid formation in yeast

(2010) Valery N. Urakov et al.   Prion

Non-Mendelian determinant [ISP+] in yeast is a nuclear-residing prion form of the global transcriptional regulator Sfp1

(2010) T. Rogoza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Type of Transmission Barrier Revealed by Study of Multiple Prion Determinants of Rnq1

(2010) Michele L. Kadnar et al.   PLoS Genetics

Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease

(2009) Angela Bithell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

FoldAmyloid: a method of prediction of amyloidogenic regions from protein sequence

(2009) S. O. Garbuzynskiy et al.   BIOINFORMATICS

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

A heritable switch in carbon source utilization driven by an unusual yeast prion

(2009) J. C.S. Brown et al.   GENES & DEVELOPMENT

TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity

(2009) Brian S. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unravelling the ultrastructure of stress granules and associated P-bodies in human cells

(2009) S. Souquere et al.   JOURNAL OF CELL SCIENCE

Cross-Seeding Fibrillation of Q/N-Rich Proteins Offers New Pathomechanism of Polyglutamine Diseases

(2009) Y. Furukawa et al.   JOURNAL OF NEUROSCIENCE

The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion

(2009) Basant K. Patel et al.   NATURE CELL BIOLOGY

The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases

(2009) Hiroshi Doi et al.   NEUROSCIENCE RESEARCH

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

(2009) C. Vance et al.   SCIENCE

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

A role for Q/N-rich aggregation-prone regions in P-body localization

(2008) M. A. M. Reijns et al.   JOURNAL OF CELL SCIENCE

Huntingtin Modulates Transcription, Occupies Gene Promoters In Vivo, and Binds Directly to DNA in a Polyglutamine-Dependent Manner

(2008) C. L. Benn et al.   JOURNAL OF NEUROSCIENCE

Epigenetic control of polyamines by the prion [PSI+]

(2008) Olivier Namy et al.   NATURE CELL BIOLOGY

Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae

(2008) Zhiqiang Du et al.   NATURE GENETICS

Sustained CPEB-Dependent Local Protein Synthesis Is Required to Stabilize Synaptic Growth for Persistence of Long-Term Facilitation in Aplysia

(2008) Maria Concetta Miniaci et al.   NEURON

Up-to-date catalogues of yeast protein complexes

(2008) Shuye Pu et al.   NUCLEIC ACIDS RESEARCH

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Prion Switching in Response to Environmental Stress

(2008) Jens Tyedmers et al.   PLOS BIOLOGY