Sequence Complexity of Amyloidogenic Regions in Intrinsically Disordered Human Proteins

Protein disorder, prion propensities, and self-organizing macromolecular collectives

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Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains

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Exon-phase symmetry and intrinsic structural disorder promote modular evolution in the human genome

(2013) Eva Schad et al.   NUCLEIC ACIDS RESEARCH

Genome-Wide Analysis of Protein Disorder in Arabidopsis thaliana: Implications for Plant Environmental Adaptation

(2013) Natalia Pietrosemoli et al.   PLoS One

A New Family of Intrinsically Disordered Proteins: Structural Characterization of the Major Phasin PhaF from Pseudomonas putida KT2440

(2013) Beatriz Maestro et al.   PLoS One

MoRFpred, a computational tool for sequence-based prediction and characterization of short disorder-to-order transitioning binding regions in proteins

(2012) Fatemeh Miri Disfani et al.   BIOINFORMATICS

The complexity and implications of yeast prion domains

(2012) Zhiqiang Du   Prion

Proteins without 3D structure: definition, detection and beyond

(2011) Ferenc Orosz et al.   BIOINFORMATICS

Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins

(2011) Randal Halfmann et al.   MOLECULAR CELL

IDEAL: Intrinsically Disordered proteins with Extensive Annotations and Literature

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UniProt Knowledgebase: a hub of integrated protein data

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Isolation of short peptide fragments from α-synuclein fibril core identifies a residue important for fibril nucleation: A possible implication for diagnostic applications

(2010) Hisashi Yagi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity

(2010) Karin M. Danzer et al.   FASEB JOURNAL

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

(2010) Sebastian Maurer-Stroh et al.   NATURE METHODS

Reduction in Structural Disorder and Functional Complexity in the Thermal Adaptation of Prokaryotes

(2010) Prasad V. Burra et al.   PLoS One

Identifying the amylome, proteins capable of forming amyloid-like fibrils

(2010) Lukasz Goldschmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biophysical characterization reveals structural disorder in the developmental transcriptional regulator LBH

(2009) Hassan Al-Ali et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ANCHOR: web server for predicting protein binding regions in disordered proteins

(2009) Z. Dosztanyi et al.   BIOINFORMATICS

FoldAmyloid: a method of prediction of amyloidogenic regions from protein sequence

(2009) S. O. Garbuzynskiy et al.   BIOINFORMATICS

Prediction of amyloid fibril-forming segments based on a support vector machine

(2009) Jian Tian et al.   BMC BIOINFORMATICS

Bioinformatical approaches to characterize intrinsically disordered/unstructured proteins

(2009) Z. Dosztanyi et al.   BRIEFINGS IN BIOINFORMATICS

Predicting intrinsic disorder in proteins: an overview

(2009) Bo He et al.   CELL RESEARCH

Biophysics of Parkinsons Disease: Structure and Aggregation of α- Synuclein

(2009) Vladimir Uversky et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

A Large Intrinsically Disordered Region in SKIP and Its Disorder-Order Transition Induced by PPIL1 Binding Revealed by NMR

(2009) Xingsheng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved Disorder Prediction by Combination of Orthogonal Approaches

(2009) Avner Schlessinger et al.   PLoS One

Short protein segments can drive a non-fibrillizing protein into the amyloid state

(2009) P. K. Teng et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Amyloidogenic determinants are usually not buried

(2009) Kimon K Frousios et al.   BMC STRUCTURAL BIOLOGY

Influence of Sequence Changes and Environment on Intrinsically Disordered Proteins

(2009) Amrita Mohan et al.   PLoS Computational Biology

Intrinsic Structural Disorder Confers Cellular Viability on Oncogenic Fusion Proteins

(2009) Hedi Hegyi et al.   PLoS Computational Biology

Prediction of Aggregation-Prone Regions in Structured Proteins

(2008) Gian Gaetano Tartaglia et al.   JOURNAL OF MOLECULAR BIOLOGY

Aggregation Propensity of the Human Proteome

(2008) Elodie Monsellier et al.   PLoS Computational Biology