The nuts and bolts of the platelet release reaction

Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol IsomerasesHighlights

(2016) Marilena Crescente et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Arf6 controls platelet spreading and clot retraction via integrin  IIb 3 trafficking

(2016) Y. Huang et al.   BLOOD

Involvement of platelets in tumor cell metastasis

(2016) Belay Tesfamariam   PHARMACOLOGY & THERAPEUTICS

B-cell–independent sialylation of IgG

(2016) Mark B. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Synaptic Vesicle Release Machinery

(2015) Josep Rizo et al.   Annual Review of Biophysics

Role of Munc13-4 as a Ca2+-dependent tether during platelet secretion

(2015) M. C. Chicka et al.   BIOCHEMICAL JOURNAL

Platelet dense granule secretion defects may obscure  -granule secretion mechanisms: evidence from Munc13-4-deficient platelets

(2015) M. T. Harper et al.   BLOOD

VAMP-7 links granule exocytosis to actin reorganization during platelet activation

(2015) S. Koseoglu et al.   BLOOD

VPS33B regulates protein sorting into and maturation of  -granule progenitor organelles in mouse megakaryocytes

(2015) D. Bem et al.   BLOOD

Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis

(2015) M. M. Ouseph et al.   BLOOD

Platelet geometry sensing spatially regulates  -granule secretion to enable matrix self-deposition

(2015) Y. Sakurai et al.   BLOOD

Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome

(2015) A. Sharda et al.   BLOOD

Platelet secretion: From haemostasis to wound healing and beyond

(2015) Ewelina M. Golebiewska et al.   BLOOD REVIEWS

Ral GTPases: crucial mediators of exocytosis and tumourigenesis

(2015) R. Shirakawa et al.   JOURNAL OF BIOCHEMISTRY

The Exocyst at a Glance

(2015) B. Wu et al.   JOURNAL OF CELL SCIENCE

Platelet secretory behaviour: as diverse as the granules … or not?

(2015) H. Heijnen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Identification of roles for the SNARE-associated protein, SNAP29, in mouse platelets

(2015) C.M. Williams et al.   PLATELETS

Ral small GTPase signaling and oncogenesis: More than just 15minutes of fame

(2014) Leanna R. Gentry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Defective release of   granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models

(2014) R. Meng et al.   BLOOD

Quantitative proteomics analysis reveals similar release profiles following specific PAR-1 or PAR-4 stimulation of platelets

(2014) Thijs C. van Holten et al.   CARDIOVASCULAR RESEARCH

SNARE-ing the structures of Sec1/Munc18 proteins

(2014) Julia K Archbold et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Platelets Support Extracellular Sialylation by Supplying the Sugar Donor Substrate

(2014) Melissa M. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelet secretion and hemostasis require syntaxin-binding protein STXBP5

(2014) Shaojing Ye et al.   JOURNAL OF CLINICAL INVESTIGATION

Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion

(2014) Qiuyu Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Copy Number Analysis of the Murine Platelet Proteome Spanning the Complete Abundance Range

(2014) Marlis Zeiler et al.   MOLECULAR & CELLULAR PROTEOMICS

Discovery and characterization of small molecules that target the GTPase Ral

(2014) Chao Yan et al.   NATURE

Reconciling the regulatory role of Munc18 proteins in SNARE-complex assembly

(2014) Asma Rehman et al.   IUCrJ

Dynamin-Related Protein-1 Controls Fusion Pore Dynamics During Platelet Granule Exocytosis

(2013) Secil Koseoglu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High Precision Platelet Releasate Definition by Quantitative Reversed Protein Profiling—Brief Report

(2013) Patrick Wijten et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

I B kinase phosphorylation of SNAP-23 controls platelet secretion

(2013) Z. A. Karim et al.   BLOOD

Advances in platelet granule biology

(2013) Secil Koseoglu et al.   CURRENT OPINION IN HEMATOLOGY

Rab27 Effectors, Pleiotropic Regulators in Secretory Pathways

(2013) Mitsunori Fukuda   TRAFFIC

The origin and function of platelet glycosyltransferases

(2012) H. H. Wandall et al.   BLOOD

Munc18b/STXBP2 is required for platelet secretion

(2012) R. Al Hawas et al.   BLOOD

Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion

(2012) S. Ye et al.   BLOOD

Granule exocytosis is required for platelet spreading: differential sorting of  -granules expressing VAMP-7

(2012) C. G. Peters et al.   BLOOD

Platelet secretion is kinetically heterogeneous in an agonist-responsive manner

(2012) D. Jonnalagadda et al.   BLOOD

Molecular determinants of platelet delta storage pool deficiencies: an update

(2012) Julien Masliah-Planchon et al.   BRITISH JOURNAL OF HAEMATOLOGY

Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets

(2012) A. HAMPSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

(2012) Ingmar B Schäfer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effect of Genetic Variation in STXBP5 and STX2 on von Willebrand Factor and Bleeding Phenotype in Type 1 von Willebrand Disease Patients

(2012) Janine E. van Loon et al.   PLoS One

Requirements for the catalytic cycle of the N-ethylmaleimide-Sensitive Factor (NSF)

(2011) Chunxia Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Quantitative immunofluorescence mapping reveals little functional coclustering of proteins within platelet  -granules

(2011) J. Kamykowski et al.   BLOOD

Proteomic analysis of palmitoylated platelet proteins

(2011) L. Dowal et al.   BLOOD

Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli

(2011) M. Chatterjee et al.   BLOOD

Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics

(2011) Julia Maria Burkhart et al.   Journal of Proteomics

Advances in our understanding of the molecular basis of disorders of platelet function

(2011) A. NURDEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The exocyst complex in exocytosis and cell migration

(2011) Jianglan Liu et al.   PROTOPLASMA

Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis

(2010) Q. Ren et al.   BLOOD

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

(2010) N. L. Smith et al.   BLOOD

Effect of Genetic Variations in Syntaxin-Binding Protein-5 and Syntaxin-2 on von Willebrand Factor Concentration and Cardiovascular Risk

(2010) Janine E. van Loon et al.   Circulation-Cardiovascular Genetics

Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets

(2009) O. Neumuller et al.   BLOOD

Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo

(2009) G. J. Graham et al.   BLOOD

Increased formation of VAMP-3-containing SNARE complexes in mast cells from VAMP-8 deficient cells

(2009) N. Tiwari et al.   INFLAMMATION RESEARCH

Platelet functions beyond hemostasis

(2009) S. S. SMYTH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA

(2009) A. A. KONDKAR et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming

(2009) Uri Ashery et al.   TRENDS IN NEUROSCIENCES

Phosphorylation of SNAP-23 by IκB Kinase 2 Regulates Mast Cell Degranulation

(2008) Kotaro Suzuki et al.   CELL

The platelet release reaction: just when you thought platelet secretion was simple

(2008) Qiansheng Ren et al.   CURRENT OPINION IN HEMATOLOGY

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

(2008) Leif E. Sander et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms

(2008) N. Puri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of Gene Variants With Incident Myocardial Infarction in the Cardiovascular Health Study

(2007) Dov Shiffman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY